scholarly journals Idiopatic Systemic Capillary Leak Syndrome Treated Successfully with High-Dose Intravenous Immunoglobulins

2015 ◽  
Vol 13 (2) ◽  
pp. 87-89
Author(s):  
Ferhat Ekinci ◽  
Utku Erdem Soyaltın ◽  
Harun Akar ◽  
Mehmet Can Ugur ◽  
Ercan Ersoy ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Clinical Management ◽  
Relevant Literature ◽  
Intravenous Immunoglobulins ◽  
Capillary Leak Syndrome ◽  
High Dose ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome

AbstractIdiopathic systemic capillary leak syndrome (ISCLS) is characterized by a triad of hypotension, hemoconcentration and hypoalbuminemia due to a shift of intravascular fluid and albumin to the extravascular area. We describe a hypovolemic patient with hemoconcentration and hypoalbuminemia who was successfully treated with high-dose intravenous immunoglobulins (IVIG). The purpose of this case report is to discuss the clinical management of idiopathic systemic capillary leak syndrome on the background of relevant literature review.

Idiopathic systemic capillary leak syndrome (Clarkson’s disease) presenting with recurrent hypovolemic shock

2021 ◽  
Vol 20 (1) ◽  
pp. 74-77
Author(s):  
Kristen Davies ◽  
◽  
Kirsty Thomas ◽  
Lorna Barton ◽  
Chris Williams ◽  
...  
Keyword(s):  
Hypovolemic Shock ◽  
Intravenous Immunoglobulins ◽  
Capillary Leak Syndrome ◽  
High Dose ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome ◽  
Compartment Syndromes ◽  
Monthly Basis ◽  
History Of ◽  
Clarkson’S Disease

A 49-year old male with a past medical history of myocardial infarction and compartment syndromes requiring fasciotomies presented on five occasions with hypovolemic shock. We describe his admissions and presumptive diagnoses which required large volumes of intravenous fluids, admission to intensive care for vasopressors and renal replacement therapy. The presentations were always precipitated by a prodrome of fatigue and pre-syncopal episodes. On his last admission, a diagnosis of Idiopathic systemic capillary leak syndrome (ISCLS), also known as Clarkson’s Disease, was reached. He is currently receiving high dose intravenous immunoglobulins on a monthly basis.

High-dose intravenous immunoglobulins dramatically reverse systemic capillary leak syndrome

2008 ◽  
Vol 36 (7) ◽  
pp. 2184-2187 ◽  
Author(s):  
Marc Lambert ◽  
David Launay ◽  
Eric Hachulla ◽  
Sandrine Morell-Dubois ◽  
Vincent Soland ◽  
...  
Keyword(s):  
Intravenous Immunoglobulins ◽  
Capillary Leak Syndrome ◽  
High Dose ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome

Idiopathic systemic capillary leak syndrome (Clarkson syndrome) in childhood: systematic literature review

2018 ◽  
Vol 177 (8) ◽  
pp. 1149-1154 ◽  
Author(s):  
Marie-Ange Bozzini ◽  
Gregorio P. Milani ◽  
Mario G. Bianchetti ◽  
Emilio F. Fossali ◽  
Sebastiano A. G. Lava
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Capillary Leak Syndrome ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome

Systemic capillary leak syndrome or Clarkson’s disease: a case report

2009 ◽  
Vol 4 (4) ◽  
pp. 357-358 ◽  
Author(s):  
Maria De Martino ◽  
Laura Sasso ◽  
Flora Pirozzi ◽  
Domenico Bonaduce
Keyword(s):  
Case Report ◽  
Capillary Leak Syndrome ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome ◽  
Clarkson’S Disease
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