scholarly journals Systemic capillary leak syndrome (Clarkson's disease) during elective pylorus-preserving pancreaticoduodenectomy: case report

2014 ◽  
Vol 18 (1) ◽  
pp. 38 ◽  
Author(s):  
Kun Moo Choi ◽  
Cheon Soo Park ◽  
Mi Hye Kim
Keyword(s):  
Case Report ◽  
Capillary Leak Syndrome ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome ◽  
Clarkson’S Disease

Systemic capillary leak syndrome or Clarkson’s disease: a case report

2009 ◽  
Vol 4 (4) ◽  
pp. 357-358 ◽  
Author(s):  
Maria De Martino ◽  
Laura Sasso ◽  
Flora Pirozzi ◽  
Domenico Bonaduce
Keyword(s):  
Case Report ◽  
Capillary Leak Syndrome ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome ◽  
Clarkson’S Disease

Capillary leak syndrome (CLS) from rituximab therapy of lymphoma

2020 ◽  
pp. 1-3
Keyword(s):  
Chemotherapy Regimen ◽  
Capillary Leak Syndrome ◽  
Plasma Extravasation ◽  
Capillary Leak ◽  
Radiological Findings ◽  
Systemic Capillary Leak Syndrome ◽  
Drug Induced ◽  
Multi Agent ◽  
Clarkson’S Disease

Capillary Leak Syndome (CLS) is characterized by plasma extravasation into the interstitium with resultant hypotension, anasarca, hemoconcentration, and hypoalbuminemia in the absence of albuminuria. Initially reported in Clarkson’s disease (systemic capillary leak syndrome, SCLS), CLS has been observed in multiple disease settings, the most common being sepsis. In Oncology, CLS has been reported more often as a complication from therapy, and less often from malignancy. In this case study, we documented clinical manifestation, laboratory features and radiological findings of CLS from rituximab therapy when employed in combination with a multi-agent chemotherapy regimen (EPOCH-R). Differentiating drug-induced CLS from sepsis, which presents with the same clinical features, is important in avoiding further exposure to rituximab, which could be fatal to the patient.

scholarly journals Systemic Capillary Leak Syndrome (Clarkson’s Disease) as a Complication of Anti–Programmed Death 1 Immunotherapy

2019 ◽  
Vol 14 (6) ◽  
pp. e131-e132 ◽  
Author(s):  
Céline Lescure ◽  
Alain Lescoat ◽  
Alexandre Salé ◽  
Yann Bazin ◽  
Loïg Duvergé ◽  
...  
Keyword(s):  
Capillary Leak Syndrome ◽  
Capillary Leak ◽  
Systemic Capillary Leak Syndrome ◽  
Programmed Death ◽  
Programmed Death 1 ◽  
Clarkson’S Disease
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