Solitary plasmocytoma of the skull: case report and review of the literature

Abstract Solitary plasmacytoma and extramedullary plasmocytoma are tumors of malignant character composed of plasma cells, with a mean age of onset at 60 years. They can appear anywhere where the reticuloendothelial system is present. Usually these tumors lead to the development of multiple myeloma in a period of time ranging from 3 to 5 years. We present a rare case handled in our neurosurgery service associated with an unusually long period of evolution.

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Pulsatile Midline Solitary Plasmacytoma in the Frontal Head Region-A Case Report”

Bangladesh Journal of Neuroscience ◽

10.3329/bjn.v32i1.57412 ◽

2016 ◽

Vol 32 (1) ◽

pp. 39-42

Author(s):

Md Atikur Rahman ◽

Aklaque Hossain Khan ◽

Kanak Kanti Barua

Keyword(s):

Multiple Myeloma ◽

Differential Diagnosis ◽

Case Report ◽

Histological Examination ◽

Plasma Cells ◽

Extramedullary Plasmacytoma ◽

Solitary Plasmacytoma ◽

Rare Entity ◽

Head Region ◽

Malignant Plasma Cell

Primary craniocerebral plasmacytomas are uncommon and represent only 0.7 % of all plasmacytomas. In this case solitary plasmacytoma in the midline frontal head region of the skull and discuss the clinical features and prognosis of this tumor. Plasmacytoma can present as multiple myeloma, solitary plasmacytoma of the bone or extramedullary plasmacytoma. Solitary plasmacytoma is a rare entity that composes of malignant plasma cells and involves the bone to form only one or two lesions without evidence of disease dissemination. It accounts for only 4% of malignant plasma cell tumors. 50 years old male was suffering from plasmacytoma in the frontal head region in our case which is pulsatile. On images showed multiple differential diagnosis but after operation histological examination revealed plasmacytoma. Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 39-42

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A rare case of plasmacytoma of mandible revealing plasma cell myeloma

Journal of Clinical Images and Medical Case Reports ◽

10.52768/2766-7820/1319 ◽

2021 ◽

Vol 2 (5) ◽

Author(s):

Hari Ram ◽

◽

Sneha Gupta ◽

Praveen Kumar Singh ◽

Shivani Sharma ◽

...

Keyword(s):

Multiple Myeloma ◽

Plasma Cell ◽

Rare Case ◽

Plasma Cells ◽

Solitary Plasmacytoma ◽

Bence Jones Protein ◽

Jaw Bones ◽

Plasma Cell Neoplasm ◽

Cell Neoplasm ◽

Single Bone

Multiple myeloma (MM) is a malignant proliferation of plasma cells with multiple foci. Plasmacytoma is a solitary plasma cell neoplasm involving a single bone. The most commonly involved bone is vertebra. Jaw bones are rarely involved as a first bone as they have lesser hematopoietic marrow. A solitary plasmacytoma may progress to multiple myeloma within few months to year. We present a case of a swelling of mandible that on further investigations confirmed the diagnosis of multiple myeloma. We have discussed the course of treatment given and its prognosis. Keywords: multiple myeloma; plasmacytoma of jaw; bence jones Protein; abnormal plasma cells; CD138.

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Solitary Intracranial Plasmacytoma in an Unusual Location – A Case Report

Nepal Journal of Neuroscience ◽

10.3126/njn.v16i1.24436 ◽

2019 ◽

Vol 16 (1) ◽

pp. 55-57

Author(s):

Suresh Bishokarma ◽

Shikher Shrestha ◽

Kajan Ranabhat ◽

Rajesh Panth

Keyword(s):

Multiple Myeloma ◽

Case Report ◽

Cerebellopontine Angle ◽

Plasma Cells ◽

Solitary Plasmacytoma ◽

Cranial Nerve Involvement ◽

Rare Form ◽

Plasma Cell Dyscrasias ◽

Systemic Manifestations ◽

Multiple Cranial Nerve

Plasmacytoma is rare form of plasma cell dyscrasias, where there is malignant proliferation of plasma cells. Solitary plasmacytoma developsin isolation without systemic manifestations of multiple myeloma (MM). We report a case of cerebellopontine angle (CPA) plasma cytoma, which masqueraded as a schwannoma with multiple cranial nerve involvement and review a literature pertaining to the same pathological entity.

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Retrobulbar secondary plasmacytoma: a case report and systematic review of the literature

Biomedical Research and Therapy ◽

10.15419/bmrat.v5i9.482 ◽

2018 ◽

Vol 5 (9) ◽

pp. 2703-2707 ◽

Cited By ~ 1

Author(s):

Mehrdad Payandeh ◽

Noorodin Karami ◽

Soode Enayati ◽

Afshin Karami ◽

Mehrnoush Aeinfar ◽

...

Keyword(s):

Systematic Review ◽

Multiple Myeloma ◽

Case Report ◽

Plasma Cells ◽

Extramedullary Plasmacytoma ◽

Therapeutic Options ◽

Review Of The Literature ◽

Orbital Involvement ◽

Therapeutic Measures ◽

Uncommon Case

Multiple myeloma is described by the proliferation of malignant plasma cells, in which orbital involvement is rare. In this report, we collected all cases with orbital multiple myeloma from 2009 to 2018 and investigated the characteristics such as sex, age, common orbital symptoms, unilateral or bilateral and different therapeutic options. Also, we reported an uncommon case of multiple myeloma that has been developed into plasmacytoma. Our patient had been initially diagnosed with multiple myeloma, but after a few months, the disease had progressed to secondary extramedullary plasmacytoma in the retrobulbar. Therapeutic measures, such as surgery to prevent its development in the patient's eye, were successful.

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