Apomab: An agonist monoclonal antibody directed against Death Receptor 5/TRAIL-Receptor 2 for use in the treatment of solid tumors

2008 ◽  
Vol 8 (8) ◽  
pp. 1167-1176 ◽  
Author(s):  
D Ross Camidge
Keyword(s):  
Monoclonal Antibody ◽  
Solid Tumors ◽  
Death Receptor ◽  
Trail Receptor ◽  
Death Receptor 5

scholarly journals Structural basis of LaDR5, a novel agonistic anti-death receptor 5 (DR5) monoclonal antibody, to inhibit DR5/TRAIL complex formation

2012 ◽  
Vol 13 (1) ◽  
pp. 40
Author(s):  
Chunxia Qiao ◽  
Meiyun Hu ◽  
Leiming Guo ◽  
Ming Lv ◽  
Zhou Lin ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Complex Formation ◽  
Death Receptor ◽  
Structural Basis ◽  
Death Receptor 5

scholarly journals Phase I Trial of Weekly Tigatuzumab, an Agonistic Humanized Monoclonal Antibody Targeting Death Receptor 5 (DR5)

2010 ◽  
Vol 25 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Andres Forero-Torres ◽  
Jatin Shah ◽  
Tina Wood ◽  
James Posey ◽  
Ronda Carlisle ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Phase I ◽  
Phase I Trial ◽  
Death Receptor ◽  
Death Receptor 5 ◽  
Humanized Monoclonal Antibody ◽  
Antibody Targeting

240 Molecular imaging of Death Receptor 5 (DR5) occupancy in-vivo by humanized monoclonal antibody CS-1008

2010 ◽  
Vol 8 (7) ◽  
pp. 78
Author(s):  
A.M. Scott ◽  
F.T. Lee ◽  
G.C. Cartwright ◽  
G.J. O'Keefe ◽  
R.A. Beckman ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Molecular Imaging ◽  
Death Receptor ◽  
Death Receptor 5 ◽  
Humanized Monoclonal Antibody

scholarly journals Bile Acids Up-regulate Death Receptor 5/TRAIL-receptor 2 Expression via a c-Jun N-terminal Kinase-dependent Pathway Involving Sp1

2003 ◽  
Vol 279 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Hajime Higuchi ◽  
Annette Grambihler ◽  
Ali Canbay ◽  
Steven F. Bronk ◽  
Gregory J. Gores
Keyword(s):  
Bile Acids ◽  
Death Receptor ◽  
Trail Receptor ◽  
Death Receptor 5 ◽  
Dependent Pathway

scholarly journals Melanoma-Directed Activation of Apoptosis Using a Bispecific Antibody Directed at MCSP and TRAIL Receptor-2/Death Receptor-5

2016 ◽  
Vol 136 (2) ◽  
pp. 541-544 ◽  
Author(s):  
Yuan He ◽  
Djoke Hendriks ◽  
Robert van Ginkel ◽  
Douwe Samplonius ◽  
Edwin Bremer ◽  
...  
Keyword(s):  
Bispecific Antibody ◽  
Death Receptor ◽  
Trail Receptor ◽  
Death Receptor 5
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