Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model

2006 ◽  
Vol 101 (1) ◽  
pp. 46-54 ◽  
Author(s):  
J. Michael Straughn ◽  
Patsy G. Oliver ◽  
Tong Zhou ◽  
Wenquan Wang ◽  
Ronald D. Alvarez ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Monoclonal Antibody ◽  
Radiation Therapy ◽  
Death Receptor ◽  
Death Receptor 5 ◽  
Cancer Model ◽  
Anti Tumor Activity

scholarly journals Structural basis of LaDR5, a novel agonistic anti-death receptor 5 (DR5) monoclonal antibody, to inhibit DR5/TRAIL complex formation

2012 ◽  
Vol 13 (1) ◽  
pp. 40
Author(s):  
Chunxia Qiao ◽  
Meiyun Hu ◽  
Leiming Guo ◽  
Ming Lv ◽  
Zhou Lin ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Complex Formation ◽  
Death Receptor ◽  
Structural Basis ◽  
Death Receptor 5

scholarly journals Phase I Trial of Weekly Tigatuzumab, an Agonistic Humanized Monoclonal Antibody Targeting Death Receptor 5 (DR5)

2010 ◽  
Vol 25 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Andres Forero-Torres ◽  
Jatin Shah ◽  
Tina Wood ◽  
James Posey ◽  
Ronda Carlisle ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Phase I ◽  
Phase I Trial ◽  
Death Receptor ◽  
Death Receptor 5 ◽  
Humanized Monoclonal Antibody ◽  
Antibody Targeting

Effect of TRA-8 Anti-Death Receptor 5 Antibody in Combination With Chemotherapy in an Ex Vivo Human Ovarian Cancer Model

2009 ◽  
Vol 19 (5) ◽  
pp. 814-819 ◽  
Author(s):  
Peter J. Frederick ◽  
James E. Kendrick ◽  
J. Michael Straughn ◽  
Debbie L. Della Manna ◽  
Patsy G. Oliver ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Ex Vivo ◽  
Death Receptor ◽  
Human Ovarian Cancer ◽  
Death Receptor 5 ◽  
Cancer Model

240 Molecular imaging of Death Receptor 5 (DR5) occupancy in-vivo by humanized monoclonal antibody CS-1008

2010 ◽  
Vol 8 (7) ◽  
pp. 78
Author(s):  
A.M. Scott ◽  
F.T. Lee ◽  
G.C. Cartwright ◽  
G.J. O'Keefe ◽  
R.A. Beckman ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Molecular Imaging ◽  
Death Receptor ◽  
Death Receptor 5 ◽  
Humanized Monoclonal Antibody
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