New opportunities in drug design of metalloproteinase inhibitors: combination between structure–function experimental approaches and systems biology

2011 ◽  
Vol 6 (5) ◽  
pp. 527-542 ◽  
Author(s):  
Netta Sela-Passwell ◽  
Alla Trahtenherts ◽  
Achim Krüger ◽  
Irit Sagi
Author(s):  
Songül Yaşar Yıldız

Glycobiology is a glycan-based field of study that focuses on the structure, function, and biology of carbohydrates, and glycomics is a sub-study of the field of glycobiology that aims to define structure/function of glycans in living organisms. With the popularity of the glycobiology and glycomics, application of computational modeling expanded in the scientific area of glycobiology over the last decades. The recent availability of progressive Wet-Lab methods in the field of glycobiology and glycomics is promising for the impact of systems biology on the research area of the glycome, an emerging field that is termed “systems glycobiology.” This chapter will summarize the up-to-date leading edge in the use of bioinformatics tools in the field of glycobiology. The chapter provides basic knowledge both for glycobiologists interested in the application of bioinformatics tools and scientists of computational biology interested in studying the glycome.


2020 ◽  
Vol 11 ◽  
Author(s):  
Annette Nicke ◽  
Chris Ulens ◽  
Jean-Francois Rolland ◽  
Victor I. Tsetlin

2017 ◽  
Vol 24 (3) ◽  
pp. 245-267 ◽  
Author(s):  
Nurbubu Moldogazieva ◽  
Innokenty Mokhosoev ◽  
Alexander Terentiev

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