Preclinical models for pediatric solid tumor drug discovery: current trends, challenges and the scopes for improvement

2012 ◽  
Vol 7 (11) ◽  
pp. 1093-1106 ◽  
Author(s):  
Sushil Kumar ◽  
Reza Bayat Mokhtari ◽  
Herman Yeger ◽  
Sylvain Baruchel
Keyword(s):  
Drug Discovery ◽  
Solid Tumor ◽  
Preclinical Models ◽  
Current Trends ◽  
Pediatric Solid Tumor

Hsp90 inhibitors deplete key anti-apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin

2004 ◽  
Vol 113 (2) ◽  
pp. 179-188 ◽  
Author(s):  
Rochelle Bagatell ◽  
Jason Beliakoff ◽  
Cynthia L. David ◽  
Marilyn T. Marron ◽  
Luke Whitesell
Keyword(s):  
Anticancer Activity ◽  
Tumor Cells ◽  
Solid Tumor ◽  
Hsp90 Inhibitors ◽  
Pediatric Solid Tumor ◽  
Apoptotic Proteins

Enhanced antitumor activity of irofulven in combination with irinotecan in pediatric solid tumor xenograft models

2004 ◽  
Vol 55 (5) ◽  
pp. 411-419 ◽  
Author(s):  
Michael H. Woo ◽  
Jennifer K. Peterson ◽  
Catherine Billups ◽  
Hua Liang ◽  
Mary-Ann Bjornsti ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Solid Tumor ◽  
Tumor Xenograft ◽  
Pediatric Solid Tumor ◽  
Xenograft Models

Current trends in epigenetic drug discovery

2012 ◽  
Vol 4 (16) ◽  
pp. 2029-2037 ◽  
Author(s):  
Diana A Stolfa ◽  
Oliver Einsle ◽  
Wolfgang Sippl ◽  
Manfred Jung
Keyword(s):  
Drug Discovery ◽  
Current Trends ◽  
Epigenetic Drug

scholarly journals The Efficacy and Safety of Apatinib in Refractory/Relapse Advanced Pediatric Solid Tumor: A Retrospective Study

2020 ◽  
Vol Volume 12 ◽  
pp. 6177-6185 ◽  
Author(s):  
Feifei Sun ◽  
Suying Lu ◽  
Zijun Zhen ◽  
Jia Zhu ◽  
Juan Wang ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Solid Tumor ◽  
Efficacy And Safety ◽  
Pediatric Solid Tumor

Postoperative Fevers in Pediatric Solid Tumor Patients

2009 ◽  
Vol 31 (7) ◽  
pp. 485-488 ◽  
Author(s):  
Eleanor Hendershot ◽  
Ann Chang ◽  
Kimberly Colapinto ◽  
J. Ted Gerstle ◽  
David Malkin ◽  
...  
Keyword(s):  
Solid Tumor ◽  
Tumor Patients ◽  
Pediatric Solid Tumor
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