scholarly journals Healing of colonic anastomosis in rats under obstructive ileus conditions

Discoveries ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. e129
Author(s):  
Kalliopi Despoudi ◽  
◽  
Ioannis Mantzoros ◽  
Orestis Ioannidis ◽  
Lydia Loutzidou ◽  
...  
Keyword(s):  
Colonic Anastomosis ◽  
Obstructive Ileus

scholarly journals GASTROSCHISIS ASSOCIATED WITH COLONIC ATRESIA - CASE REPORT

2018 ◽  
pp. 81
Author(s):  
Ivona Đorđević ◽  
Anđelka Slavković ◽  
Zoran Marjanović ◽  
Dragoljub Živanović ◽  
Milan Petrović
Keyword(s):  
Case Report ◽  
Surgical Procedure ◽  
Rare Case ◽  
Colonic Anastomosis ◽  
Mechanical Obstruction ◽  
Postoperative Course ◽  
Colonic Atresia ◽  
Primary Surgery ◽  
Obstructive Ileus

We present an extremely rare case of gastroschisis associated with colonic atresia, anomaly seen in only 1.5-5% of all gastroschisis patients. Surgery for this anomaly can be very difficult due to the concomitant inflammation or other anomalies (mesenterium communae, volvulus, etc). Although prolonged intestinal dismotility is expected in these patients, mechanical obstruction must not be excluded in postoperative course, as it is explained in this case. Our case report demonstrates that primary colonic anastomosis is safe and well tolerated surgical procedure for these patients and that obstructive ileus is possible days after primary surgery and must not be overlooked.

scholarly journals Human Oral Mucosal Stem Cells Reduce Anastomotic Leak in an Animal Model of Colonic Surgery

2021 ◽  
pp. 1-8
Author(s):  
Ilan Kent ◽  
Cyrus Jahansouz ◽  
Amandeep Ghuman ◽  
Baruch Shpitz ◽  
Debora Kidron ◽  
...  
Keyword(s):  
Stem Cells ◽  
Anastomotic Leak ◽  
Murine Model ◽  
Colonic Anastomosis ◽  
Colon Surgery ◽  
Leak Rate ◽  
Colonic Surgery ◽  
Colon Wall ◽  
Anastomotic Leak Rate ◽  
Suture Anastomosis

<b><i>Background:</i></b> Anastomotic leak is regarded as one of the most feared complications of bowel surgery; avoiding leaks is a major priority. Attempts to reduce or eliminate leaks have included alternate anastomotic techniques. Human oral mucosa stem cells (hOMSC) are self-renewing and expandable cells derived from buccal mucosa. Studies have shown that hOMSC can accelerate tissue regeneration and wound healing. The objective of this study was to evaluate whether hOMSC can decrease anastomotic leak rates in a murine model of colon surgery. <b><i>Methods:</i></b> Two experiments were performed. In the first study, mice underwent colonic anastomosis using five interrupted sutures. hOMSC (<i>n</i> = 7) or normal saline (NS; <i>n</i> = 17) was injected into the colon wall at the site of the anastomosis. To evaluate whether hOMSC can impact anastomotic healing, the model was stressed by repeating the first experiment, reducing the number of sutures used for the construction of the anastomosis from five to four. Either hOMSC (<i>n</i> = 8) or NS (<i>n</i> = 20) was injected at the anastomosis. All mice that survived were sacrificed on postoperative day 7. Anastomotic leak rate, mortality, daily weight, and daily wellness scores were compared. <b><i>Results:</i></b> In the five-suture anastomosis, there were no differences in anastomotic leak rate, mortality, or daily weight. Mice that received hOMSC had significantly higher wellness scores on postoperative day 2 (<i>p</i> &#x3c; 0.05). In the four-suture anastomosis, there was a significant decrease in leak rate (70% [NS] vs. 25% [hOMSC], <i>p</i> = 0.029) and higher wellness scores in mice that received hOMSC (<i>p</i> &#x3c; 0.05). <b><i>Conclusion:</i></b> Our study suggests that injecting hOMSC at the colonic anastomosis can potentially reduce anastomotic leak and improve postoperative wellness in a murine model of colon surgery.

Effect of Recombinant Human Granulocyte/Macrophage Colony-Stimulating Factor on the Healing of Colonic Anastomosis in Rats

2001 ◽  
Vol 14 (4) ◽  
pp. 221-225 ◽  
Author(s):  
Seher Demirer ◽  
Neriman Sengül ◽  
Aydin Inan ◽  
Aydan Eroglu ◽  
Cihan Bumin ◽  
...  
Keyword(s):  
Colonic Anastomosis ◽  
Colony Stimulating Factor ◽  
Macrophage Colony Stimulating Factor ◽  
Macrophage Colony ◽  
Stimulating Factor

Effects of Intraperitoneal Bevacizumab Administration on Colonic Anastomosis and Early Postoperative Adhesion Formation

2013 ◽  
Vol 20 (6) ◽  
pp. 559-565 ◽  
Author(s):  
Hasan Karanlik ◽  
Atilla Kurt ◽  
Enver Kunduz ◽  
Kursat Serin ◽  
Sezer Saglam ◽  
...  
Keyword(s):  
Colonic Anastomosis ◽  
Adhesion Formation ◽  
Postoperative Adhesion

The Effects of Duration of CO2Pneumoperitoneum on Colonic Anastomosis

2008 ◽  
Vol 21 (4) ◽  
pp. 177-181 ◽  
Author(s):  
Ilter Ozer ◽  
Murat Ulas ◽  
Metin Ercan ◽  
Yusuf B. Ozogul ◽  
Neslihan Zengin ◽  
...  
Keyword(s):  
Colonic Anastomosis

The effect of N G-nitro L-arginine methyl ester on colonic anastomosis after increased intra-abdominal pressure

2006 ◽  
Vol 392 (2) ◽  
pp. 197-202 ◽  
Author(s):  
C. Polat ◽  
Y. Arıkan ◽  
C. Gokce ◽  
F. Aktepe ◽  
G. Akbulut ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Colonic Anastomosis ◽  
Abdominal Pressure

The Effects of Beta-Aminopropionitrile on Colonic Anastomosis in Rats

2004 ◽  
Vol 17 (4) ◽  
pp. 211-219 ◽  
Author(s):  
Turker Bulut ◽  
Yilmaz Bilsel ◽  
Hakan Yanar ◽  
Sumer Yamaner ◽  
Emre Balik ◽  
...  
Keyword(s):  
Colonic Anastomosis

One-layer continuously sutured colonic anastomosis

1993 ◽  
Vol 80 (11) ◽  
pp. 1450-1451 ◽  
Author(s):  
W. H. F. Thomson ◽  
M. H. E. Robinson
Keyword(s):  
Colonic Anastomosis
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