This paper discusses an evaluation method of creep-fatigue lives of YH61 single crystal superalloy under multiaxial loading at high temperature. Three types of creep-fatigue tests were performed using three types of the single crystalsuperalloy specimens at 1173K. They were push-pull tests using solid bar specimens, tension-torsion tests using hollow cylinder specimens and biaxial tension-compression tests using cruciform specimens. Anisotropic strain and Mises stress in combination with frequency modified fatigue equation were applied for evaluating the creep-fatigue lives in the three types of tests. The former parameter gave a relatively large scatter but the latter parameter a small scatter in the correlation.