Prospective comparison of primary wound closure with tissue- adhesive versus suture materials

Abstract Establishing nontension primary wound closure of various soft tissue flaps is paramount for optimal postsurgical wound healing. Surgical procedures that require clinical flap manipulation, such as those used with traditional periodontal therapy, periodontal plastic cosmetic surgery, hard and soft tissue regeneration, and the excision of pathologic tissue, also require excellence in execution. Also paramount to clinical success is a thorough understanding of the various techniques of surgery, suturing, and the materials currently available to ensure the desired clinical results. This article will discuss the rationale of specific suturing techniques and suture materials to help the clinician obtain optimal wound closure.

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A Comparison of 2-Octyl Cyanoacrylate Adhesives versus Conventional Suture Materials for Eyelid Wound Closure in Rabbits

Korean Journal of Ophthalmology ◽

10.3341/kjo.2011.25.2.121 ◽

2011 ◽

Vol 25 (2) ◽

pp. 121 ◽

Cited By ~ 10

Author(s):

Hee-Bae Ahn ◽

Dong-Min Shin ◽

Mee-Sook Roh ◽

Woo-Jin Jeung ◽

Woo-Chan Park ◽

...

Keyword(s):

Wound Closure ◽

Suture Materials

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Comparison of primary and delayed wound closure of dog-bite wounds

Veterinary and Comparative Orthopaedics and Traumatology ◽

10.3415/vcot-12-04-0053 ◽

2013 ◽

Vol 26 (03) ◽

pp. 204-207 ◽

Cited By ~ 7

Author(s):

H. Xiaowei ◽

X. Yunbei ◽

L. Zhenhua ◽

Y. Yeqing ◽

Y. Jiaqi ◽

...

Keyword(s):

Infection Rate ◽

Primary Closure ◽

Wound Closure ◽

Systemic Infection ◽

Dog Bite ◽

Cosmetic Appearance ◽

Primary Wound Closure ◽

Bite Wounds ◽

Delayed Closure ◽

Closure Group

Summary Background: Primary bite wound suturing in the emergency department remains controversial in some cases. Objective: We conducted a study to investigate the infection rate and cosmetic appearance between primary wound closure and delayed wound closure in dog bite wounds in humans. Methods: All patients with bite wounds were treated with oral antibiotic medications. We adopted a randomized cohort study, dividing the patients who needed wound closure into two groups: 60 patients for primary closure, and 60 patients for delayed closure, and compared the infection rate and wound cosmetic appearance scores. Results: In the primary closure group, four people (6.7%) developed a wound infection without systemic infection. In the delayed closure group, three people (5%) developed a wound infection (p = 0.093), but there were not any patients that developed a systemic infection. Thirty-three patients (55%) in the primary closure group had optimal cosmetic scores, whereas 20 patients (33.3%) in the delayed closure group had optimal cosmetic scores (p = 0.012). Conclusion: Although primary wound closure for dog bites may be associated with a higher infection rate, the cosmetic appearance after primary closure was still acceptable.

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Evaluation of Preventive Treatment Protocols for Patients under Antiresorptive Therapy Undergoing Tooth Extraction at a Swiss University Clinic

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18189924 ◽

2021 ◽

Vol 18 (18) ◽

pp. 9924

Author(s):

Ellen Pick ◽

Nicolas Leuenberger ◽

Irina Kuster ◽

Nicole Selina Stutzmann ◽

Bernd Stadlinger ◽

...

Keyword(s):

Tooth Extraction ◽

Wound Closure ◽

Oral Surgery ◽

Preventive Treatment ◽

Osteonecrosis Of The Jaw ◽

Antiresorptive Therapy ◽

Related Factors ◽

Treatment Protocols ◽

Primary Wound Closure ◽

Mucoperiosteal Flap

Antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is a dreaded complication in patients with compromised bone metabolism. The purpose of the present study was to examine the occurrence of ARONJ and its related factors among patients with a history of antiresorptive therapy undergoing tooth extraction using preventive protocols at a Swiss university clinic. Data were retrospectively pooled from health records of patients having received a surgical tooth extraction between January 2015 and April 2020 in the Clinic of Cranio-Maxillofacial and Oral surgery, University of Zurich. A total of 970 patients received an extraction with flap elevation or wound closure during this period. A total of 104 patients could be included in the study. Furthermore, variables including age, gender, smoking, risk profile, choice, indication and duration of antiresorptive therapy, number of extractions, extraction site, surgical technique, choice and duration of antibiotics as well as the presence of postoperative inflammatory complications were assessed. Overall, 4 patients developed ARONJ (incidence of 3.8%) after tooth extraction at the same location, without previous signs of osteonecrosis. Preventive methods included predominantly primary wound closure using a full thickness mucoperiosteal flap and prolonged perioperative antibiotic prophylaxis. In accordance with current literature, the applied protocol showed a reliable outcome in preventing ARONJ when a tooth extraction is required.

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