scholarly journals Acetylcholine, Outer Hair Cell Electromotility, and the Cochlear Amplifier

1997 ◽  
Vol 17 (6) ◽  
pp. 2212-2226 ◽  
Author(s):  
Peter Dallos ◽  
David Z. Z. He ◽  
Xi Lin ◽  
István Sziklai ◽  
Samir Mehta ◽  
...  
Keyword(s):  
Hair Cell ◽  
Outer Hair Cell ◽  
Cochlear Amplifier

Active Hair Bundle Movements and the Cochlear Amplifier

2003 ◽  
Vol 14 (06) ◽  
pp. 325-338 ◽  
Author(s):  
Anthony Ricci
Keyword(s):  
Hearing Loss ◽  
Hair Cell ◽  
Sensorineural Hearing Loss ◽  
Outer Hair Cell ◽  
Sensorineural Hearing ◽  
Hair Bundle ◽  
Cochlear Amplifier ◽  
Active Process ◽  
Slow Adaptation ◽  
Active Processes

The “active process” is a term used to describe amplification and filtering processes that are essential for obtaining the exquisite sensitivity of hearing organs. Understanding the components of the active process is important both for our understanding of the normal physiology of hearing and because perturbations of the cochlear amplifier may lead to such maladies as threshold shifts (both temporary and permanent), tinnitus, sensorineural hearing loss and presbicusis. To date the cochlear amplifier has largely been attributed to outer hair cell electro motility; however, recent evidence suggests, that active properties of the hair bundle may also be important. Most likely both somatic motility and active hair bundle movements contribute to establishing the cochlear active process. This paper reviews recent evidence regarding known active processes in the hair bundle gating compliance, and fast and slow adaptation.

Outer hair cell somatic, not hair bundle, motility is the basis of the cochlear amplifier

2008 ◽  
Vol 11 (7) ◽  
pp. 746-748 ◽  
Author(s):  
Marcia M Mellado Lagarde ◽  
Markus Drexl ◽  
Victoria A Lukashkina ◽  
Andrei N Lukashkin ◽  
Ian J Russell
Keyword(s):  
Hair Cell ◽  
Outer Hair Cell ◽  
Hair Bundle ◽  
Cochlear Amplifier

Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier

Nature ◽  
2002 ◽  
Vol 419 (6904) ◽  
pp. 300-304 ◽  
Author(s):  
M. Charles Liberman ◽  
Jiangang Gao ◽  
David Z. Z. He ◽  
Xudong Wu ◽  
Shuping Jia ◽  
...  
Keyword(s):  
Hair Cell ◽  
Outer Hair Cell ◽  
Cochlear Amplifier
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