scholarly journals Entorhinal Cortex Lesion in Adult Rats Induces the Expression of the Neuronal Chondroitin Sulfate Proteoglycan Neurocan in Reactive Astrocytes

1999 ◽  
Vol 19 (22) ◽  
pp. 9953-9963 ◽  
Author(s):  
Carola A. Haas ◽  
Uwe Rauch ◽  
Niklas Thon ◽  
Tobias Merten ◽  
Thomas Deller
Keyword(s):  
Chondroitin Sulfate ◽  
Entorhinal Cortex ◽  
Reactive Astrocytes ◽  
Chondroitin Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Adult Rats ◽  
Cortex Lesion ◽  
Entorhinal Cortex Lesion

Detection of chondroitin sulfates and decorin in developing fetal and neonatal rat lung

2002 ◽  
Vol 282 (3) ◽  
pp. L484-L490 ◽  
Author(s):  
Yiqiong Wang ◽  
Kaori Sakamoto ◽  
Jody Khosla ◽  
Philip L. Sannes
Keyword(s):  
Extracellular Matrix ◽  
Chondroitin Sulfate ◽  
Wide Distribution ◽  
Neonatal Rat ◽  
Chondroitin Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Rat Lung ◽  
Adult Rats ◽  
Chondroitin Sulfates ◽  
Monospecific Antibodies

Chondroitin sulfates and their related proteoglycans are components of extracellular matrix that act as key determinants of growth and differentiation characteristics of developing lungs. Changes in their immunohistochemical distribution during progressive organ maturation were examined with monospecific antibodies to chondroitin sulfate, a nonbasement membrane chondroitin sulfate proteoglycan, and the specific chondroitin sulfate-containing proteoglycan decorin in whole fetuses and lungs from newborn and adult rats. Alveolar and airway extracellular matrix immunostained heavily in the prenatal rat for both chondroitin sulfate and chondroitin sulfate proteoglycan, whereas decorin was confined to developing airways and vessels. These sites retained their respective levels of reactivity with all antibodies through 1–10 days postnatal but thereafter became progressively more diminished and focal in alveolar regions. The heavy staining seen early in development was interpreted to reflect a significant and wide distribution of chondroitin sulfates, chondroitin sulfate proteoglycans, and decorin in rapidly growing tissues, whereas the reduced and more focal reactivity observed at later time points coincided with known focal patterns of localization of fibrillar elements of the extracellular matrix and a more differentiated state.

Entorhinal cortex lesion does not alter reelin messenger RNA expression in the dentate gyrus of young and adult rats

Neuroscience ◽  
2000 ◽  
Vol 97 (1) ◽  
pp. 25-31 ◽  
Author(s):  
C.A. Haas ◽  
T. Deller* ◽  
Z. Krsnik ◽  
A. Tielsch ◽  
A. Woods ◽  
...  
Keyword(s):  
Dentate Gyrus ◽  
Entorhinal Cortex ◽  
Messenger Rna ◽  
Rna Expression ◽  
Adult Rats ◽  
Cortex Lesion ◽  
Entorhinal Cortex Lesion

scholarly journals Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production

Glia ◽  
2018 ◽  
Vol 67 (1) ◽  
pp. 68-77 ◽  
Author(s):  
Alwin Kamermans ◽  
Kirsten E. Planting ◽  
Kees Jalink ◽  
Jack van Horssen ◽  
Helga E. de Vries
Keyword(s):  
Multiple Sclerosis ◽  
Chondroitin Sulfate ◽  
Reactive Astrocytes ◽  
Chondroitin Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Neuronal Outgrowth

Neurotractin/kilon promotes neurite outgrowth and is expressed on reactive astrocytes after entorhinal cortex lesion

2005 ◽  
Vol 29 (4) ◽  
pp. 580-590 ◽  
Author(s):  
Michael Schäfer ◽  
Anja U. Bräuer ◽  
Nicolai E. Savaskan ◽  
Fritz G. Rathjen ◽  
Thomas Brümmendorf
Keyword(s):  
Neurite Outgrowth ◽  
Entorhinal Cortex ◽  
Reactive Astrocytes ◽  
Cortex Lesion ◽  
Entorhinal Cortex Lesion
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