scholarly journals Kv4.3 channel dysfunction contributes to trigeminal neuropathic pain manifested with orofacial cold hypersensitivity in rats

2021 ◽  
pp. JN-RM-2036-20
Author(s):  
Hirosato Kanda ◽  
Jennifer Ling ◽  
Ya-Ting Chang ◽  
Ferhat Erol ◽  
Viacheslav Viatchenko-Karpinski ◽  
...  
2000 ◽  
Vol 5 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Allan S Gordon

Practitioners are often presented with patients who complain bitterly of facial pain. The trigeminal nerve is involved in four conditions that are sometimes mixed up. The four conditions - trigeminal neuralgia, trigeminal neuropathic pain, postherpetic neuralgia and atypical facial pain - are discussed under the headings of clinical features, differential diagnosis, cause and treatment. This article should help practitioners to differentiate one from the other and to manage their care.


2021 ◽  
pp. 105247
Author(s):  
Nontawat Chuinsiri ◽  
David Edwards ◽  
Vsevolod Telezhkin ◽  
Christopher J. Nile ◽  
Fréderic Van der Cruyssen ◽  
...  

2014 ◽  
Vol 289 (10) ◽  
pp. 7025-7037 ◽  
Author(s):  
Kang-Wu Li ◽  
Yanhui Peter Yu ◽  
Chunyi Zhou ◽  
Doo-Sik Kim ◽  
Bin Lin ◽  
...  

2018 ◽  
Vol 19 (6) ◽  
pp. 626-634 ◽  
Author(s):  
Weihua Ding ◽  
Zerong You ◽  
Shiqian Shen ◽  
Jinsheng Yang ◽  
Grewo Lim ◽  
...  

Neuroscience ◽  
2019 ◽  
Vol 414 ◽  
pp. 299-310 ◽  
Author(s):  
Yuping Wang ◽  
Peng Cao ◽  
Lisheng Mei ◽  
Weiwei Yin ◽  
Yu Mao ◽  
...  

2013 ◽  
Vol 35 (3) ◽  
pp. E10 ◽  
Author(s):  
Alberto Feletti ◽  
Giannantonio Zanata Santi ◽  
Francesco Sammartino ◽  
Marzio Bevilacqua ◽  
Piero Cisotto ◽  
...  

Object Peripheral nerve field stimulation has been successfully used for many neuropathic syndromes. However, it has been reported as a treatment for trigeminal neuropathic pain or persistent idiopathic facial pain only in the recent years. Methods The authors present a review of the literature and their own series of 6 patients who were treated with peripheral nerve stimulation for facial neuropathic pain, reporting excellent pain relief and subsequent better social relations and quality of life. Results On average, pain scores in these patients decreased from 10 to 2.7 on the visual analog scale during a 17-month follow-up (range 0–32 months). The authors also observed the ability to decrease trigeminal pain with occipital nerve stimulation, clinically confirming the previously reported existence of a close anatomical connection between the trigeminal and occipital nerves (trigeminocervical nucleus). Conclusions Peripheral nerve field stimulation of the trigeminal and occipital nerves is a safe and effective treatment for trigeminal neuropathic pain and persistent idiopathic facial pain, when patients are strictly selected and electrodes are correctly placed under the hyperalgesia strip at the periphery of the allodynia region.


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