scholarly journals Properties and Functional Role of Voltage-Dependent Potassium Channels in Dendrites of Rat Cerebellar Purkinje Neurons

2003 ◽  
Vol 23 (13) ◽  
pp. 5698-5707 ◽  
Author(s):  
Marco Martina ◽  
Gui Lan Yao ◽  
Bruce P. Bean
2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Swati S Kunduri ◽  
Mohammed A Nayeem ◽  
Dovenia S Ponnoth ◽  
Stephen Tilley ◽  
S. Jamal Mustafa

1978 ◽  
Vol 71 (1) ◽  
pp. 101-120 ◽  
Author(s):  
J S Pepose ◽  
J E Lisman

The steady-state slope conductance of Limulus ventral photoreceptors increases markedly when the membrane is depolarized from rest. The ionic basis of this rectification has been examined with a voltage-clamp technique. Tail currents that occur when membrane potential is repolarized after having been depolarized have been identified. The tail currents reverse direction at a voltage that becomes more positive when Ko is increased. Rectification is reduced by extracellular 4-aminopyridine and by intracellular injection of tetra-ethyl-ammonium (TEA). These results indicate that the membrane rectification around resting potential is due primarily to voltage-sensitive K+ channels. The increase in gK caused by depolarization is not mediated by a voltage-dependent rise in in Cai++, since intracellular injection of Ca++ causes a decrease rather than an increase in slope conductance. TEA can be used to examine the functional role of the K+ channels because it blocks them without substantially affecting the light-activated Na+ conductance. The effect of TEA on response-intensity curves shows that the K+ channels serve to compress the voltage range of receptor potentials.


2008 ◽  
Vol 591 (1-3) ◽  
pp. 171-176 ◽  
Author(s):  
Praveen K. Gupta ◽  
Jaganathan Subramani ◽  
Marie Dennis Marcus Leo ◽  
Anurag S. Sikarwar ◽  
Subhashree Parida ◽  
...  

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