PHARMACOLOGICAL CHARACTERIZATION OF THE FUNCTIONAL ROLE OF CALCIUM-ACTIVATED POTASSIUM CHANNELS IN PLATELETS

2016 ◽  
Vol 32 (10) ◽  
pp. S260
Author(s):  
V. Back ◽  
F. Plane ◽  
P. Jurasz
2020 ◽  
Vol 11 ◽  
Author(s):  
David Weisbrod

Calcium-activated potassium channels are a heterogeneous family of channels that, despite their different biophysical characteristics, structures, and pharmacological signatures, play a role of transducer between the ubiquitous intracellular calcium signaling and the electric variations of the membrane. Although this family of channels was extensively described in various excitable and non-excitable tissues, an increasing amount of evidences shows their functional role in the heart. This review aims to focus on the physiological role and the contribution of the small and intermediate calcium-activated potassium channels in cardiac pathologies.


Neuron ◽  
1995 ◽  
Vol 14 (3) ◽  
pp. 645-650 ◽  
Author(s):  
Owen B McManus ◽  
Lisa M.H Helms ◽  
Leo Pallanck ◽  
Barry Ganetzky ◽  
Richard Swanson ◽  
...  

Biochemistry ◽  
2007 ◽  
Vol 46 (43) ◽  
pp. 12152-12163 ◽  
Author(s):  
Izhack Cherny ◽  
Martin Overgaard ◽  
Jonas Borch ◽  
Yaron Bram ◽  
Kenn Gerdes ◽  
...  

2020 ◽  
Vol 222 ◽  
pp. 02050
Author(s):  
Marat Lutfulin ◽  
Darya Zaripova ◽  
Oksana Moiseeva ◽  
Semen Vologin ◽  
Ayslu Mardanova

Identification of patterns of formation of bacterial communities of the rhizosphere and rhizoplane of potato (Solanum tuberosum L.), the most important agricultural crop, is necessary for the introduction and maintenance of sustainable organic farming. The purpose of this work was the study of the biodiversity of the bacterial microbiota of the rhizosphere and rhizoplane of Early Zhukovsky potato, cultivated on gray forest soils. Comparative analysis based on sequencing of the 16S R RNA gene showed a significant difference in the representation of different groups of bacteria in these potato root compartments. Thus, the proportions of the dominant bacteria in the rhizosphere and rhizoplane of the Proteobacteria phylum reach 47.66% ± 7.22 % and 86.35 % ± 0.53%, respectively (P < 0.05). In contrast, the representation of phylum Bacteroidetes and Firmicutes in the rhizosphere is significantly higher and reaches 41.45 % ± 10.42% and 6.49 % ± 3.23%, respectively, compared to the rhizoplane (7.84 % ± 1.24 % and 0.43 % ± 0.48 %, (P < 0.05). At the same time, Actinobacteria phylum bacteria are present in both compartments in approximately equal amounts (4.40 % ± 1.81% in the rhizosphere and 5.37 % ± 1.42% in the rhizoplane). Thus, it was found that potato forms different bacterial communities in the rhizosphere and rhizoplane in quantitative proportions, which is probably determined by the functional role of these microorganisms in the plant physiology.


2019 ◽  
Vol 11 (10) ◽  
pp. 2876 ◽  
Author(s):  
Alessandra Durazzo

This special issue, “The Close Linkage between Nutrition and Environment through Biodiversity and Sustainability: Local Foods, Traditional Recipes, and Sustainable Diets” is focused on the close correlation between the potential benefits and “functional role” of a food and the territory, including papers on the characterization of local foods and traditional recipes, on the promotion of traditional dietary patterns and sustainable diets.


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