COMPOSITION EN ACIDES AMINES DE THYROGLOBULINES PROVENANT DE SUJETS EUTHYROIDIENS ET GOITREUX

1966 ◽  
Vol 53 (2) ◽  
pp. 297-302 ◽  
Author(s):  
Janine Bismuth ◽  
Marcel Rolland ◽  
Serge Lissitzky

ABSTRACT Amino acid composition of S19 thyroglobulin purified from three normal human thyroid glands, a hyperthyroid goiter, two hypothyroid familial goiters and a euthyroid goiter, has been determined. No significant differences in amino acid composition has been observed.

1964 ◽  
Vol 42 (3) ◽  
pp. 341-344 ◽  
Author(s):  
B. E. March ◽  
Jacob Biely ◽  
K. R. Pastro

Chicks fed diets containing 26% of protein had larger thyroid glands than did chicks fed diets containing 17.5% of protein. Thyroidal uptake of I131 per chick was also greater in the chicks fed the higher level of protein. The basal diets were deficient in methionine. Supplementation of the diets with lysine, which would aggravate the amino acid imbalance, significantly depressed thyroidal uptake of I131 per chick. It is concluded that the amino acid composition of dietary protein, as well as the protein level in the diet, affects thyroid activity in the chick.


1966 ◽  
Vol 53 (2) ◽  
pp. 286-296 ◽  
Author(s):  
Marcel Rolland ◽  
Janine Bismuth ◽  
Joseph Fondarai ◽  
Serge Lissitzky

ABSTRACT Amino acid composition of S19 thyroglobulin of eight species (seven mammals and one bird) has been determined. A statistical study of the results shows significant variations of all amino acids except valine, leucine and cystine. Beef, horse and hog thyroglobulins have a very similar, if not identical, amino acid composition. The remarkable constancy of the valine, leucine and cystine contents as well as the sum of the amino acids with hydrophobic side chain, suggests a great similarity of the secondary and tertiary structures of the studied thyroglobulins.


2014 ◽  
Author(s):  
Alexandra Jayne Kermack ◽  
Ying Cheong ◽  
Nick Brook ◽  
Nick Macklon ◽  
Franchesca D Houghton

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