Improvement in spinal involvement with zoledronic acid in pediatric patients with chronic recurrent multifocal osteomyelitis: a case series

2017 ◽  
Author(s):  
Marie-Eve Robinson ◽  
Anne Marie Sbrocchi ◽  
Rosie Scuccimarri
Keyword(s):  
Zoledronic Acid ◽  
Pediatric Patients ◽  
Case Series ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Spinal Involvement ◽  
Multifocal Osteomyelitis

scholarly journals Chronic recurrent multifocal osteomyelitis - A case series from India

2018 ◽  
Vol 52 (6) ◽  
pp. 672 ◽  
Author(s):  
PoojaPrakash Mallya ◽  
AnandPrahalad Rao ◽  
Shashi Ranjani ◽  
Jyothi Raghuram
Keyword(s):  
Case Series ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Multifocal Osteomyelitis

Imaging of chronic recurrent multifocal osteomyelitis of childhood first presenting with isolated primary spinal involvement

2003 ◽  
Vol 32 (6) ◽  
pp. 328-336 ◽  
Author(s):  
S. E. Anderson ◽  
P. Heini ◽  
M. J. Sauvain ◽  
E. Stauffer ◽  
L. Geiger ◽  
...  
Keyword(s):  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Spinal Involvement ◽  
Multifocal Osteomyelitis

Chronic recurrent multifocal osteomyelitis: Effectiveness of cyclic intravenous pamidronate therapy in pain relief and spinal involvement

Bone ◽  
2007 ◽  
Vol 40 (6) ◽  
pp. S34-S35
Author(s):  
C.T. Cowell ◽  
H.K. Gleeson ◽  
E. Wiltshire ◽  
K. Grimwood ◽  
J. Briody ◽  
...  
Keyword(s):  
Pain Relief ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Spinal Involvement ◽  
Intravenous Pamidronate ◽  
Multifocal Osteomyelitis ◽  
Pamidronate Therapy

Spinal involvement in chronic recurrent multifocal osteomyelitis (CRMO) in childhood and effect of pamidronate

2010 ◽  
Vol 169 (9) ◽  
pp. 1105-1111 ◽  
Author(s):  
Toni Hospach ◽  
Micha Langendoerfer ◽  
Tekla von Kalle ◽  
Jan Maier ◽  
Guenther E. Dannecker
Keyword(s):  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Spinal Involvement ◽  
Multifocal Osteomyelitis

scholarly journals Contiguous Three-Level Vertebral Collapse in Thoracic Spine: A Novel Presentation of Chronic Recurrent Multifocal Osteomyelitis in 12 years old and Review of Literature

2021 ◽  
Vol 11 (6) ◽  
Author(s):  
Dheeraj Batheja ◽  
Sudarshan Munigangaiah ◽  
Harsha H Jayanna ◽  
Aashish Ghodke
Keyword(s):  
Thoracic Spine ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Autoimmune Disorder ◽  
Childhood And Adolescence ◽  
Management Options ◽  
Spinal Involvement ◽  
Multifocal Osteomyelitis ◽  
Body Magnetic Resonance Imaging ◽  
Inflammatory Drugs ◽  
Full Body

Introduction: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoimmune disorder of childhood and adolescence which often manifests as recurring episodes of inflammatory bone pains. Spinal involvement is rare; however, recent studies advocate full body magnetic resonance imaging in all suspected cases to pick up asymptomatic lesions early to prevent complications. Spinal involvement may manifest as fractures, scoliosis, or kyphotic deformity. Case Report: We present a case of a 12-year-old boy who had three-level involvement of thoracic spine, T6-T8, and was worked up and managed for pathological fracture of spine. He underwent biopsy for the same and was later diagnosed as CRMO. Here, we discuss the diagnostic challenges involved in CRMO, need for biopsy, and the management options available. Conclusions: Identifying CRMO is challenging and remains a diagnosis of exclusion. Nonsteroidal anti-inflammatory drugs often constitute the first line of treatment and other drugs such as bisphosphonates and biologics such as TNF-alpha antagonists are reserved for more severe cases. Although CRMO is considered a benign disease, recent data suggest up to 50% rate of residual impairments despite optimal management. Keywords: Chronic recurrent multifocal osteomyelitis, spine, contiguous, child.

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