When thyroid function tests remain deranged despite treatment

2019 ◽  
Author(s):  
Aaisha Saqib ◽  
Adrian Li ◽  
Paul Carroll
Keyword(s):  
Thyroid Function ◽  
Thyroid Function Tests ◽  
Function Tests

In a bind: abnormal thyroid function tests

2019 ◽  
Author(s):  
Catriona Hilton ◽  
Farhan Ahmed ◽  
Asif Ali
Keyword(s):  
Thyroid Function ◽  
Thyroid Function Tests ◽  
Function Tests

scholarly journals Falsely diagnosed thyrotoxicosis caused by anti-streptavidin antibodies and pre-wash procedures

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Takuya Ishikawa ◽  
Hiroyuki Sakai ◽  
Tokutaro Itaya ◽  
Suwanai Hirotsugu ◽  
Jumpei Shikuma ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Magnetic Particle ◽  
Thyroid Function Tests ◽  
Case Presentation ◽  
Analytical Interference ◽  
Function Tests ◽  
Inappropriate Treatment ◽  
Published Report ◽  
Old Japanese ◽  
Polyethylene Glycol Precipitation

Abstract Background Anti-streptavidin antibodies are causal determinants of analytical interference during Thyroid function tests, and numerous reports have detailed such interference, with anti-streptavidin antibodies attracting attention. Case presentation We conducted a straightforward investigation of interference due to anti-streptavidin antibodies, with a case of a 60-year-old Japanese man who consulted our department for inconsistencies between his clinical course and Thyroid function tests. Experiments were conducted using Cobas8000 e602, which employs assay procedures with pre-wash to evaluate FT4 and FT3 levels. Conclusions To our knowledge, this is the first published report to clearly investigate such interferences using a combination of polyethylene glycol precipitation, heterophilic blocking tube precipitation, streptavidin-coated magnetic particle precipitation, and different instruments with or without pre-wash. Clinicians should consider that interferences caused by anti-streptavidin antibodies could lead to a misdiagnosis of thyrotoxicosis. Moreover, discussions between laboratory specialists, clinicians, and manufacturers are required to identify interferences and avoid unnecessary examinations and inappropriate treatment.

scholarly journals What should be done when thyroid function tests do not make sense?

2011 ◽  
Vol 74 (6) ◽  
pp. 673-678 ◽  
Author(s):  
Mark Gurnell ◽  
David J. Halsall ◽  
V. Krishna Chatterjee
Keyword(s):  
Thyroid Function ◽  
Thyroid Function Tests ◽  
Function Tests

scholarly journals THYROID FUNCTION TESTS

1969 ◽  
Vol 22 (1) ◽  
pp. 113-114 ◽  
Author(s):  
R. F. Harvey
Keyword(s):  
Thyroid Function ◽  
Thyroid Function Tests ◽  
Function Tests
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