scholarly journals A Model Selection Approach for the Identification of Quantitative Trait Loci in Experimental Crosses, Allowing Epistasis

Genetics ◽  
2008 ◽  
Vol 181 (3) ◽  
pp. 1077-1086 ◽  
Author(s):  
Ani Manichaikul ◽  
Jee Young Moon ◽  
Śaunak Sen ◽  
Brian S. Yandell ◽  
Karl W. Broman

Genetics ◽  
2010 ◽  
Vol 187 (2) ◽  
pp. 611-621 ◽  
Author(s):  
Ping Wang ◽  
John A. Dawson ◽  
Mark P. Keller ◽  
Brian S. Yandell ◽  
Nancy A. Thornberry ◽  
...  


Genetics ◽  
2007 ◽  
Vol 176 (3) ◽  
pp. 1865-1877 ◽  
Author(s):  
Nengjun Yi ◽  
Daniel Shriner ◽  
Samprit Banerjee ◽  
Tapan Mehta ◽  
Daniel Pomp ◽  
...  


Genetica ◽  
2008 ◽  
Vol 135 (3) ◽  
pp. 429-437 ◽  
Author(s):  
Ming Fang ◽  
Dan Jiang ◽  
Huijiang Gao ◽  
Dongxiao Sun ◽  
Runqing Yang ◽  
...  


Genetics ◽  
2002 ◽  
Vol 161 (2) ◽  
pp. 931-938
Author(s):  
Dirk-Jan de Koning ◽  
Henk Bovenhuis ◽  
Johan A M van Arendonk

Abstract In this article, the quantitative genetic aspects of imprinted genes and statistical properties of methods to detect imprinted QTL are studied. Different models to detect imprinted QTL and to distinguish between imprinted and Mendelian QTL were compared in a simulation study. Mendelian and imprinted QTL were simulated in an F2 design and analyzed under Mendelian and imprinting models. Mode of expression was evaluated against the H0 of a Mendelian QTL as well as the H0 of an imprinted QTL. It was shown that imprinted QTL might remain undetected when analyzing the genome with Mendelian models only. Compared to testing against a Mendelian QTL, using the H0 of an imprinted QTL gave a higher proportion of correctly identified imprinted QTL, but also gave a higher proportion of false inference of imprinting for Mendelian QTL. When QTL were segregating in the founder lines, spurious detection of imprinting became more prominent under both tests, especially for designs with a small number of F1 sires.



Genetics ◽  
2005 ◽  
Vol 170 (3) ◽  
pp. 1333-1344 ◽  
Author(s):  
Nengjun Yi ◽  
Brian S. Yandell ◽  
Gary A. Churchill ◽  
David B. Allison ◽  
Eugene J. Eisen ◽  
...  


2004 ◽  
Vol 36 (6) ◽  
pp. 601 ◽  
Author(s):  
T Mark Beasley ◽  
Dongyan Yang ◽  
Nengjun Yi ◽  
Daniel C Bullard ◽  
Elizabeth L Travis ◽  
...  




2007 ◽  
Vol 51 (12) ◽  
pp. 6423-6434 ◽  
Author(s):  
Andreas Baierl ◽  
Andreas Futschik ◽  
Małgorzata Bogdan ◽  
Przemysław Biecek


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