scholarly journals Serum Paraoxonase 1 (PON1) Concentration as a Marker of Left Ventricular Mass Index (LVMI) and Atherosclerosis in Hemodialysis Patients

2010 ◽  
Vol 22 (4) ◽  
pp. 199-209
Author(s):  
Kei MATSUMOTO ◽  
Makoto WATANABE ◽  
Maho OMORI ◽  
Hirokazu HONDA ◽  
Hiroaki HATTORI ◽  
...  
2012 ◽  
Vol 36 (6) ◽  
pp. 517-524 ◽  
Author(s):  
Robert Ekart ◽  
Vojko Kanič ◽  
Breda Pečovnik-Balon ◽  
Sebastjan Bevc ◽  
Benjamin Dvoršak ◽  
...  

2015 ◽  
Vol 68 (9-10) ◽  
pp. 324-330 ◽  
Author(s):  
Nada Dimkovic ◽  
Igor Mitic ◽  
Branislav Andric ◽  
Branislav Lilic-Havidza ◽  
Rosa Jelacic ◽  
...  

Introduction. Suboptimal correction of anemia is associated with increased prevalence of cardiovascular diseases and increased morbidity and mortality of pre-dialysis and dialysis patients. The aim of the study was to compare the effect of optimal vs. suboptimal correction of anemia in hemodialysis patients with left ventricular hypertrophy. Material and Methods. The study included 50 patients, 32 males and 18 females, their mean age being 49.4?11.8 years, from five hemodialysis centers (Clinical Hospital Center Zvezdara, Beograd, Clinical Center Novi Sad, hospitals in Krusevac, Pirot and Zrenjanin). The patients had suboptimal hemoglobin level in spite of therapy (7.8?3.8 g/dl). In addition, the most important inclusion criteria was the left ventricular mass index above 160 g/m2 and the primary efficacy parameter was a decrease in the left ventricular mass index during 12 month study period. Results. During the study, the number of patients who reached their hemoglobin >12 g/dl increased and the target hemoglobin (12-13 g/dl) was achieved in 24 (52%) of patients at the end of the study. At the same time, the left ventricular mass index significantly decreased as compared with the initial values (p=0.014). The left ventricular mass index was not significantly decreased in the patients who did not achieve the target hemoglobin level (207?65 vs. 217?38 g, p=ns) as compared with the patients who achieved the target hemoglobin (179?32 g/ m2 vs. 197?38 g/m2, p=0.007). The left ventricular ejection fraction did not change significantly during the study period. Conclusion. Anemia correction with erythropoietin ? resulted in the significantly corrected left ventricular hypertrophy in hemodialysis patients who had had a suboptimal hemoglobin level. Our results have shown that correction of left ventricular hypertrophy is possible with hemoglobin value of 12 g/dl at least.


Nephron ◽  
1993 ◽  
Vol 65 (2) ◽  
pp. 212-214 ◽  
Author(s):  
John D. Harnett ◽  
Brendan Murphy ◽  
Peter Collingwood ◽  
Linda Purchase ◽  
Gloria Kent ◽  
...  

2006 ◽  
Vol 39 (5) ◽  
pp. 1149-1155
Author(s):  
Shunsuke Goto ◽  
Naoya Igaki ◽  
Kazuki Yokota ◽  
Hirotaka Komaba ◽  
Maki Tanaka ◽  
...  

VASA ◽  
2013 ◽  
Vol 42 (4) ◽  
pp. 284-291 ◽  
Author(s):  
Seong-Woo Choi ◽  
Hye-Yeon Kim ◽  
Hye-Ran Ahn ◽  
Young-Hoon Lee ◽  
Sun-Seog Kweon ◽  
...  

Background: To investigate the association between ankle-brachial index (ABI), left ventricular hypertrophy (LVH) and left ventricular mass index (LVMI) in a general population. Patients and methods: The study population consisted of 8,246 people aged 50 years and older who participated in the baseline survey of the Dong-gu Study conducted in Korea between 2007 and 2010. Trained research technicians measured LV mass using mode M ultrasound echocardiography and ABI using an oscillometric method. Results: After adjustment for risk factors and common carotid artery intima-media thickness (CCA-IMT) and the number of plaques, higher ABIs (1.10 1.19, 1.20 - 1.29, and ≥ 1.30) were significantly and linearly associated with high LVMI (1.10 - 1.19 ABI: β, 3.33; 95 % CI, 1.72 - 4.93; 1.20 - 1.29 ABI: β, 6.51; 95 % CI, 4.02 - 9.00; ≥ 1.30 ABI: β, 14.83; 95 % CI, 6.18 - 23.48). An ABI of 1.10 - 1.19 and 1.20 - 1.29 ABI was significantly associated with LVH (1.10 - 1.19 ABI: OR, 1.35; 95 % CI, 1.19 - 1.53; 1.20 - 1.29 ABI: OR, 1.59; 95 % CI, 1.31 - 1.92) and ABI ≥ 1.30 was marginally associated with LVH (OR, 1.73; 95 % CI, 0.93 - 3.22, p = 0.078). Conclusions: After adjustment for other cardiovascular variables and CCA-IMT and the number of plaques, higher ABIs are associated with LVH and LVMI in Koreans aged 50 years and older.


Sign in / Sign up

Export Citation Format

Share Document