scholarly journals Analysis of a Chlamydia epidemic model with pulse vaccination strategy in a random environment

2018 ◽  
Vol 23 (4) ◽  
pp. 457-474 ◽  
Author(s):  
Guruprasad Samantaa ◽  
Shyam Pada Bera

In this paper, we have considered a dynamical model of Chlamydia disease with varying total population size, bilinear incidence rate, and pulse vaccination strategy in a random environment. It has been shown that the Chlamydia epidemic model has global positive solutions and, under some conditions, it admits a unique positive periodic disease-free solution, which is globally exponentially stable in mean square. We have defined two positive numbers R1 and R2 (< R1). It is proved that the susceptible population will be persistent in the mean and the disease will be going to extinct if R1 < 1 and the susceptible population as well as the disease will be weakly persistent in the mean if R2 > 1. Our analytical findings are explained through numerical simulation, which show the reliability of our model from the epidemiological point of view.

2005 ◽  
Vol 13 (02) ◽  
pp. 131-150 ◽  
Author(s):  
I. A. MONEIM ◽  
D. GREENHALGH

An SIRS epidemic model with general periodic vaccination strategy is analyzed. This periodic vaccination strategy is discussed first for an SIRS model with seasonal variation in the contact rate of period T = 1 year. We start with the case where the vaccination strategy and the contact rate have the same period and then discuss the case where the period of the vaccination strategy is LT, where L is an integer. We investigate whether a periodic vaccination strategy may force the epidemic dynamics to have periodic behavior. We prove that our SIRS model has a unique periodic disease free solution (DFS) whose period is the same as that of the vaccination strategy, which is globally asymptotically stable when the basic reproductive number R0 is less than or equal to one in value. When R0 > 1, we prove that there exists a non-trivial periodic solution of period the same as that of the vaccination strategy. Some persistence results are also discussed. Threshold conditions for these periodic vaccination strategies to ensure that R0 ≤ 1 are derived.


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