Late Vascular Occlusion of Central Lines in Pediatric Malignancies

PEDIATRICS ◽  
1998 ◽  
Vol 101 (2) ◽  
pp. e7-e7 ◽  
Author(s):  
J. A. Wilimas ◽  
M. Hudson ◽  
B. Rao ◽  
X. Luo ◽  
L. Lott ◽  
...  
Author(s):  
Lama Charafeddine ◽  
Mariam Anka ◽  
Therese Saad ◽  
Christelle Tayeh ◽  
Lama Charafeddine

Neonatal thrombosis is a well-described morbidity occurring in the neonatal intensive care unit. Critically ill neonates are most vulnerable to developing thrombosis with serious complications. Fingers and toes ischaemia secondary to vascular occlusion following central lines insertion remains an uncommon occurrence. The therapeutic approach for peripheral tissue injury using local warming, anticoagulants, thrombolytics or topical hyaluronidase showed limited benefits and potential side effects. Here we report an unusual case of finger ischaemia treated successfully using topical nitroglycerine. This complements previous reports confirming the efficacy and safety of this drug and highlighting its potential benefit in neonates.


Author(s):  
João F. Barbieri ◽  
Mateus F. Camilo de Lima ◽  
Isabela Imbriani Ferreira ◽  
João P. Gomes ◽  
Shirko Ahmadi

2013 ◽  
Vol 20 (17) ◽  
pp. 2254-2271 ◽  
Author(s):  
C. Gasparini ◽  
L. Vecchi Brumatti ◽  
L. Monasta ◽  
G. Zauli

2014 ◽  
Vol 14 (14) ◽  
pp. 1179-1188 ◽  
Author(s):  
Emanuela Turillazzi ◽  
Maria Neri ◽  
Stefania Bello ◽  
Irene Riezzo ◽  
Vittorio Fineschi

2012 ◽  
Vol 10 (6) ◽  
pp. 756-761 ◽  
Author(s):  
Zhou Zhou ◽  
Donald L. Yee ◽  
Prasenjit Guchhait

Author(s):  
KS Gurusamy ◽  
Y Kumar ◽  
BR Davidson

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Jean-François Hak ◽  
Farouk Tradi ◽  
Mickael Bobot ◽  
Pauline Brige ◽  
Paul Habert ◽  
...  

Objective. To evaluate the vascular occlusion and midterm tissue toxicity properties of a combination of ethylene-vinyl alcohol (EVOH) (Squid 18®) (75%) and alcohol (25%)—Alco-Squid 18—in a swine model. Materials and Methods. Alco-Squid 18 (75% Squid 18® mixed with 25% alcohol) (AS18) was compared to embolization with 96% alcohol alone and to embolization with Squid 18® (S18®) alone. An arteriovenous malformation (AVM) model was created in group 1 (n = 2). Each AVM model was then embolized with AS18 or S18® alone with evaluation of a ratio between the volume of embolic agent divided by the volume of the AVM (evaluated by CT). For group 2 (n = 5), each agent was tested on three different kidneys (upper pole kidney artery). Pre- and postinterventional CTs, angiographies, blood alcohol content dosages, and histological studies (3 months postintervention) were performed. Results. AS18 has better distal distribution than S18® alone, both in the kidneys (mean capsule-S18® distance: 3.9 mm (±0.23) and mean capsule-AS18 distance: 2.3 mm (±0.11) ( p = 0.029 ) and in the AVM model. Histological exploration found a higher rate of tubular necrosis with AS18 compared with S18® alone and alcohol alone (3.78 ± 0.44 compared to 2.33 ± 1.22 p   =  0 . 012 and 1.22 ± 0.67 p   < 0   . 0001 ). The blood alcohol content was negligible in all cases. Conclusion. AS18 can suggest a better distal sclerotic and embolic character as compared with S18® alone without systemic toxicity.


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