Congenital Cytomegalovirus Infection in Twin Pregnancies: Viral Load in the Amniotic Fluid and Pregnancy Outcome

PEDIATRICS ◽  
2003 ◽  
Vol 112 (2) ◽  
pp. e153-e157 ◽  
Author(s):  
T. Lazzarotto ◽  
L. Gabrielli ◽  
M. P. Foschini ◽  
M. Lanari ◽  
B. Guerra ◽  
...  
Keyword(s):  
Viral Load ◽  
Amniotic Fluid ◽  
Pregnancy Outcome ◽  
Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
Twin Pregnancies

Blood viral load in the diagnostic workup of congenital cytomegalovirus infection

2020 ◽  
Vol 122 ◽  
pp. 104231 ◽  
Author(s):  
Mina Smiljkovic ◽  
Jean-Baptiste Le Meur ◽  
Brigitte Malette ◽  
Isabelle Boucoiran ◽  
Anne-Frédérique Minsart ◽  
...  
Keyword(s):  
Viral Load ◽  
Cytomegalovirus Infection ◽  
Diagnostic Workup ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
Blood Viral Load

scholarly journals Change in Viral Load during Antiviral Therapy Is Not Useful for the Prediction of Hearing Dysfunction in Symptomatic Congenital Cytomegalovirus Infection

2021 ◽  
Vol 10 (24) ◽  
pp. 5864
Author(s):  
Takumi Kido ◽  
Yuki Kyono ◽  
Shutaro Suga ◽  
Ruka Nakasone ◽  
Shinya Abe ◽  
...  
Keyword(s):  
Viral Load ◽  
Retrospective Study ◽  
Antiviral Therapy ◽  
Whole Blood ◽  
Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
Viral Loads ◽  
Significant Difference ◽  
Cytomegalovirus Infections

For symptomatic congenital cytomegalovirus infections (CCMVI), the usefulness of changes in viral load during valganciclovir (VGCV) treatment for the prediction of hearing dysfunction (HD) is unclear. To determine the utility of viral load change in the whole blood or urine for the prediction of HD, we performed a retrospective study to compare viral load changes during VGCV treatment between CCMVI infants with (n = 12) or without (n = 8) HD at six months of corrected age, whose blood and urine viral loads were measured continuously for eight weeks from April 2009 to December 2019. There was no significant difference in the changes in both the blood and urine viral loads after the initiation of VGCV treatment between CCMVI infants between the groups. Moreover, this negative result was maintained in the analysis for each six weeks or six months treatment period. In conclusion, the change in viral load during antiviral therapy is not useful for the prediction of HD at six months of corrected age in symptomatic CCMVI.

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