Refractory Pneumocystis carinii Infection in Chronic Granulomatous Disease: Successful Treatment with Granulocytes

PEDIATRICS ◽  
1979 ◽  
Vol 64 (6) ◽  
pp. 935-938
Author(s):  
F. Karup Pedersen ◽  
K. Staehr Johansen ◽  
Joergen Rosenkvist ◽  
lnge Tygstrup ◽  
Niels H. Valerius
Keyword(s):  
Chronic Granulomatous Disease ◽  
Humoral Immunity ◽  
Successful Treatment ◽  
Pneumocystis Carinii Pneumonia ◽  
Pneumocystis Carinii ◽  
Granulomatous Disease ◽  
Severe Infections ◽  
Pneumocystis Carinii Infection ◽  
Cellular And Humoral Immunity

Pneumocystis carinii pneumonia developed in an 11-year-old girl with chronic granulomatous disease who had normal cellular and humoral immunity. The patient remained febrile during treatment with sulfame-thoxazole-trimethoprim and pentamidine but became afebrile when treated with a series of 12 granulocyte transfusions combined with sulfamethoxazole-trimethoprim. In addition to documenting P carinii infection in chronic granulomatous disease our findings suggest that granulocyte transfusions may be of value in the treatment of severe infections in chronic granubomatous disease.

Chronic Granulomatous Disease and Pneumocystis carinii Pneumonia

PEDIATRICS ◽  
1982 ◽  
Vol 69 (1) ◽  
pp. 133-134
Author(s):  
Allen D. Adinoff ◽  
Richard B. Johnston ◽  
Jale Dolen ◽  
Mary Ann South
Keyword(s):  
Chronic Granulomatous Disease ◽  
Molecular Oxygen ◽  
Pneumocystis Carinii Pneumonia ◽  
Pneumocystis Carinii ◽  
Enteric Bacteria ◽  
High Energy ◽  
Granulomatous Disease ◽  
Energy Metabolites

Chronic granulomatous disease (CGD) is a syndrome characterized by recurrent purulent infections of the skin, lungs, and reticuloendothelial organs. The underlying defect is an inability of phagocytes to convert molecular oxygen into high-energy metabolites that contribute to microbial death. Infections are primarily due to staphylococci, enteric bacteria, fungi, and occasionally mycobacteria.1 An 11-year-old girl with CGD was reported to have pneumonia due to P carinii.2 We have found a second case of CGD with pneumonia due to P carinii.

Successful treatment of acne with isotretinoin in chronic granulomatous disease

2011 ◽  
Vol 21 (1) ◽  
pp. 111-112
Author(s):  
Egidio BARBI ◽  
Irene BERTI ◽  
Marta MINUTE ◽  
Floriana ZENNARO
Keyword(s):  
Chronic Granulomatous Disease ◽  
Successful Treatment ◽  
Granulomatous Disease

scholarly journals Common Severe Infections in Chronic Granulomatous Disease

2014 ◽  
Vol 60 (8) ◽  
pp. 1176-1183 ◽  
Author(s):  
B. E. Marciano ◽  
C. Spalding ◽  
A. Fitzgerald ◽  
D. Mann ◽  
T. Brown ◽  
...  
Keyword(s):  
Chronic Granulomatous Disease ◽  
Granulomatous Disease ◽  
Severe Infections

Successful Treatment of Systemic Exophiala dermatitidis Infection in a Patient with Chronic Granulomatous Disease

1992 ◽  
Vol 14 (1) ◽  
pp. 235-242 ◽  
Author(s):  
R. T. Kenney ◽  
K. J. Kwon-Chung ◽  
A. T. Waytes ◽  
D. A. Melnick ◽  
H. I. Pass ◽  
...  
Keyword(s):  
Chronic Granulomatous Disease ◽  
Successful Treatment ◽  
Granulomatous Disease ◽  
Exophiala Dermatitidis
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