Quality assurance of rapid on-site evaluation of CT-guided fine-needle aspiration cytology of lung nodules

2013 ◽  
Vol 154 (1) ◽  
pp. 28-32 ◽  
Author(s):  
Mihály Bak ◽  
Judit Hidvégi ◽  
Judit Andi ◽  
Mária Bahéry ◽  
Eszter Kovács ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Average Diameter ◽  
Needle Aspiration ◽  
Lung Nodules ◽  
Aspiration Cytology ◽  
Ct Guided ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Introduction: The methods available for the diagnosis of lung cancer include radiologic, cytologic and pathologic procedures. Aims: The aim of this study was to determine the quality assurance of CT guided fine needle aspiration cytology of lung nodules. Methods: Cytology results were rated to 4 categories (positive; suspicious; negative; not representative). All cytology reports were compared with the final histology diagnosis. Results: A total of 128 patients underwent CT-guided percutaneous fine-needle aspiration biopsy cytology (63 males; 65 females; mean age 62.8 years). Smears were adequate in 99 cases and inadequate in 29 cases. The average diameter of the nodules was 3.28 cm. Thirty three (25.6%) of the cases were histologically verified and 2 falsely negative and 2 falsely positive cases were detected. The sensitivity and the positive predictive value were 88.8% and 88.8%, respectively. Pneumothorax developed in 7 (5.4%) cases. Conclusion: These results suggest that CT-guided transthoracic fine needle aspiration cytology has a high diagnostic accuracy and an acceptable complication rate. The auditing valves of the results meet the proposed threshold values. Orv. Hetil., 2013, 154, 28–32.

Quality assurance of fine-needle aspiration cytology of the organized mammography screening

2010 ◽  
Vol 151 (32) ◽  
pp. 1295-1298 ◽  
Author(s):  
Mihály Bak ◽  
Éva Konyár ◽  
Ferenc Schneider ◽  
Mária Bidlek ◽  
Éva Szabó ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Fine Needle Aspiration ◽  
Mammography Screening ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

A Nemzeti Népegészségügyi Program az emlőrák szervezett szűrését biztosítja. Célkitűzés: Dolgozatunk célja a szervezett emlőrákszűrés során a mammográfia, illetve ultrahangvizsgálatokkal nem negatív elváltozások aspirációs citológiai diagnózisainak minőségbiztosítása. Módszer: A citológiai diagnózisokat 5 kategóriába (C1, C2, C3, C4, C5) soroltuk. A citológiai módszer diagnosztikus érzékenységét a szövettani eredményekhez viszonyítva elemeztük. Eredmények: Összesen 47718 mammográfiás és ultrahangvizsgálattal a kóros emlőelváltozásokból 1361 citológiai vizsgálatot végeztünk. A leggyakoribb diagnózis benignus (805 eset, 59, 1%), illetve carcinoma (187 eset, 13,7%) volt. Az összesített pozitív, negatív esetek számításánál a szenzitivitás 91%, a specificitás 88%, a pozitív prediktív érték 96,6%, a negatív prediktív érték 71%-nak (p<0,001) bizonyult. Megbeszélés: Megállapítottuk, hogy tanulmányunkban az emlőelváltozások vékonytű-aspirációs citológiai vizsgálatainak minőségbiztosítási eredményei megfelelnek, és több tekintetben jobbak a nemzetközileg elvárt követelményeknél.

COMPUTED TOMOGRAPHY CORRELATION OF THORACIC LESIONS WITH TRANSTHORACIC FINE NEEDLE ASPIRATION CYTOLOGY AND BIOPSY

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Rajneesh Madhok ◽  
Ashish Gupta ◽  
Lalit Singh ◽  
Tanu Agarwal
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Ct Guided ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology ◽  
Adequate Tissue

INTRODUCTION: The study is an attempt to evaluate the sensitivity, specificity, positive predictive value, negative predictive value, p Value and complications of CT guided thoracic interventions fine needle aspiration cytology and core biopsy which are used for diagnosing benign and malignant thoracic lesions. MATERIAL AND METHODS: Study included 102 Patients (87 males and 15 females) with age group ranged from 15 to 87 years.A total of 143 CT guided interventions (84 FNAC’s and 59 core biopsies) were performed in 102 patients. The tissue obtained was sent to the laboratory for histopathological and cytological analysis for a final diagnosis which would contribute to patient management. RESULTS: All( 59) core biopsies were successful in procuring adequate tissue for histopathological analysis and the yield of core biopsies was 100% .However out of 84 FNAC’s only 4 were unsuccessful in procuring adequate tissue with a failure rate of 4.8%. Post procedural biopsy complications were only three (2.1%) which were small pneumothorax. There were 75 malignant lesions and 23 benign lesions based on cytology and histopathology (4 were excluded due to inadequate sample). There was good agreement between benign and malignant lesions diagnosed on CT and that diagnosed by pathology. The most common benign and malignant lesions were granulomatous lesion and squamous cell carcinoma. CONCLUSION: Percutaneous CT guided interventions like core biopsy and fine needle aspirations cytology are simple minimal invasive procedures with good patient acceptance and low morbidity and almost negligible mortality. CT guided interventions should be performed early for diagnosis of thoracic lesions.

CT-Guided Fine-Needle Aspiration Cytology of Solitary Pulmonary Nodules*

CHEST Journal ◽  
1997 ◽  
Vol 112 (2) ◽  
pp. 423-425 ◽  
Author(s):  
Luigi Santambrogio ◽  
Mario Nosotti ◽  
Nadia Bellaviti ◽  
Gianni Pavoni ◽  
Ferdinando Radice ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Pulmonary Nodules ◽  
Needle Aspiration ◽  
Solitary Pulmonary Nodules ◽  
Aspiration Cytology ◽  
Ct Guided ◽  
Fine Needle ◽  
Needle Aspiration Cytology

scholarly journals CT-Guided Percutaneous Fine Needle Aspiration Cytology of Pulmonary Mass.

2013 ◽  
Vol 11 (1) ◽  
pp. 37-41
Author(s):  
Rajive Raj Shahi ◽  
Mukunda Singh Shrestha ◽  
Sujata Pant ◽  
Sunil Singh ◽  
Dinesh Maharjan
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Lung Lesion ◽  
Aspiration Cytology ◽  
Ct Guided ◽  
Lung Lesions ◽  
Fine Needle ◽  
Atypical Cells ◽  
Needle Aspiration Cytology

Introduction: Following the first study of Computed tomography guided trans thoracic biopsy of lung lesion by Haaga and Alfidi in 1976, CT guided transthoracic biopsy has been widely used for confirming the diagnosis of suspicious lung lesions. This study is aimed to assess the effectiveness of Transthoracic percutaneous fi ne needle aspiration cytology and frequency of associated complications. Methods: A retrospective, hospital based study was performed between 11/06/2008 and 1/12/2009 at Department of Radiology, Shree Birendra Hospital, Kathmandu, Nepal. Thirty nine consecutive cases of lung lesions who underwent Trans Thoracic Percutaneous Fine Needle Aspiration Cytology (TTFNAC) under CT guidance were analysed. Smears of the aspirated material were evaluated by the pathology consultant (cytopathological evaluation) for adequacy. Results: There was adequate material for a cytopathological diagnosis in thirty four (87.18 %) cases. Two cases were hemorrhagic while three cases revealed only reactive cells thus inadequate and non representative case constituted (12.8 %). Eight cases were reported as benign (23.53 %). Twenty three samples (67.65%) were reported as definite malignant cases and three cases (8.82%) showed atypical cells, suggestive of malignancy. Squamous cell carcinoma was the single most frequent histological diagnosis (12 cases). Conclusions: The FNAC of lung is useful, safe and economical technique providing 87% diagnostic accuracy for lung mass without significant increase in complications. Medical Journal of Shree Birendra Hospital; Jan-June 2012/vol.11/Issue1/37-41 DOI: http://dx.doi.org/10.3126/mjsbh.v11i1.7766

scholarly journals Adequacy of Cytologic Samples by Ultrasound-Guided Percutaneous Transthoracic Fine-Needle Aspiration Cytology of Peripheral Pulmonary Nodules for Morphologic Diagnosis and Molecular Evaluations: Comparison With Computed Tomography–Guided Percutaneous Transthoracic Fine-Needle Aspiration Cytology

2019 ◽  
Vol 144 (3) ◽  
pp. 361-369 ◽  
Author(s):  
Immacolata Cozzolino ◽  
Andrea Ronchi ◽  
Gaetana Messina ◽  
Marco Montella ◽  
Floriana Morgillo ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Pulmonary Nodules ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Ct Guided ◽  
Fine Needle ◽  
The Mean ◽  
Needle Aspiration Cytology ◽  
Mean Time

Context.— Fine-needle aspiration cytology (FNAC) of pulmonary nodules is usually guided by computed tomography (CT), whereas ultrasonography (US) is generally considered not applicable for such purposes. Objective.— To evaluate the clinical applicability and diagnostic utility of US-guided transthoracic FNAC of peripheral pulmonary nodules. Design.— Ultrasonography-guided transthoracic FNAC was obtained from 40 selected patients with peripheral, subpleural, and paravertebral pulmonary nodules. Air-dried and Diff-Quik–stained smears were used for rapid on-site evaluation; additional smears were alcohol fixed for Papanicolaou staining. Cell blocks were set up for immunocytochemical and molecular studies; in 2 cases, a flow cytometry evaluation was also performed. The series was compared to 40 CT-guided pulmonary FNAC samples from patients with pleural, peripheral, and paravertebral pulmonary nodules, to evaluate differences in terms of diagnostic rate, time of execution, safety, and cost. Results.— The US-guided FNAC samples had results that were adequate and representative in 95% of cases. No significant differences were observed between the 2 groups in terms of diagnostic rate, number of passes, and cellularity of both smears and cell blocks. The mean time needed for the execution of US-guided FNAC was 13.1 minutes, whereas the mean time for CT-guided FNAC was 23.6 minutes. Thus, US-guided FNAC was significantly more rapid than CT-guided pulmonary FNAC. Because pneumothorax occurred in 1 individual who underwent US-guided FNAC and in 9 who underwent CT-guided FNAC, we might conclude that US-guided FNAC is a significantly safer procedure. Finally, comparing the costs of both procedures, US-guided FNAC is less expensive. Conclusions.— Our experience showed an elevated clinical applicability and diagnostic utility of US-guided transthoracic FNAC for selected pulmonary nodules.

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