scholarly journals Central Pontine Myelinolysis in a Child: Clinical Case

2021 ◽  
Vol 18 (6) ◽  
pp. 492-497
Author(s):  
Nailya F. Akhmetgaleeva ◽  
El’vira M. Yausheva ◽  
Klara Z. Bahtiyarova

Background. Central pontine myelinolysis (CPM) is limited symmetric non-inflammatory demyelination in the middle part of pontine. This disease is based on electrolyte balance disorders. Although CPM was firstly described in adults, but it can also occur in children. Every new case of CPM in children has undeniable interest and high scientific and practical significance due to its low incidence. Clinical case description. The child, 7 years old, had acute development, lethargy, multiple vomiting, subfebrile fever, pains in epigastric region. It has happened after drinking an unknown herb growing in the yard and previously covered with the insecticide "Akarin", according to the mother. The child was hospitalized in the pediatric department at the place of residence. The patient developed strabismus, swallowing disorder, and muscle weakness on infusion therapy. Biochemical blood test has shown hypokalemia and hyponatremia. Head MRI has shown symmetrical focal lesion of heterogeneous structure in pontine. Conclusion. Distinctive feature of this case is the development of CPM in a child on the ongoing therapy of hypokalemia and hyponatremia. The timely provision of qualified medical care has favoured the child's recovery.

Author(s):  
Anoop AS ◽  
Lakshmiprasad L. Jadhav ◽  
Sruthy Nair ◽  
Rohan Mohandas

A 56 year old male patient was admitted to S.D.M Ayurveda Hospital, Hassan, Karnataka with the confirmed diagnosis of Central Pontine Myelinolysis (CPM) on 11/12/17. The chief complaints were weakness of both hands and legs, stiffness in both hands and legs, pain in both shoulder joints, slurred speech, difficulty in walking with gait changes. H/O chronic alcoholism. MRI brain showed pontine and basal ganglia diffusion restriction - Acute Pontine Myelinolysis. The serum electrolyte showed serum sodium level as 128 mmol/litre. This disease can be understood as Samana Avruta Vyana in hyponatremic encephalopathy stage and the stage of myelinolysis can be understood as Sarvanga Vata with Kapha Avruta Udana and Vyana. After clinical evaluation, Avarana Chikitsa was started followed by Kevala Vatika Chikitsa and significant improvement was seen. Significant result was observed in subjective and objective parameters after the treatment. The patient was discharged with oral medications for 1 month.


2006 ◽  
Vol 28 (3) ◽  
pp. 360-366 ◽  
Author(s):  
Suresh Kumar ◽  
Marjorie Fowler ◽  
Eduardo Gonzalez-Toledo ◽  
S. L. Jaffe

2008 ◽  
Vol 21 (4) ◽  
pp. 390-391 ◽  
Author(s):  
Fuat H. Saner ◽  
Susanne Koeppen ◽  
Marco Meyer ◽  
Matthias Kohnle ◽  
Stefan Herget-Rosenthal ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Matthew Rumschlag ◽  
Joseph A. Prahlow ◽  
Rudolph J. Castellani ◽  
Amanda O. Fisher-Hubbard

2003 ◽  
Vol 14 (3-4) ◽  
pp. 103-107 ◽  
Author(s):  
Tatia M. C. Lee ◽  
Crystal C. Y. Cheung ◽  
Esther Y. Y. Lau ◽  
Amanda Mak ◽  
Leonard S. W. Li

The case of a 67-year-old right-handed Chinese man with Central Pontine Myelinolysis [CPM] is described to illustrate the resulting cognitive and emotional disturbances. A comparison of the data in this report with that in published studies suggests that ethnicity does not seem to have much effect on the symptoms of CPM. Possible underlying neural-pathological mechanisms are discussed. This case further substantiates the speculation that the brainstem plays a role in higher cognitive processes and emotional regulation.


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