Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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Published By Charaka Publishers

2456-3110
Updated Tuesday, 14 September 2021

2020 ◽  
Vol 5 (06) ◽  
pp. 102-108
Author(s):  
H Pampanna Gouda ◽  
Seema MB ◽  
Ravindra Angadi

This article attempts to clear the dogma that exists in the preparation of Kshara Ghrita with reference to its critical final stage of Siddhi Laxanas. Palasha Kshara Ghrita (PKG) prepared from the Kshara of Palasha (Grewia asiatica) mentioned in Rasa Tarangini, which is indicated in the treatment of Granthi (tumor) is taken for the study. The present article is an extract of all the observations made during the pharmaceutical study of PKG. All these observations will be of great help when we go for large scale production. The study has tried to establish the ratios of Dravadravyas with Kshara, besides addressing the type of vessels appropriate in such preparations. After preparation of sample in different vessels, these were subjected to analytical study using relevant analytical parameters to find out any difference. During pharmaceutical process Copper vessel was found appropriate on the lines of pharmaceutical preparations. The analytical report of samples reveals no much difference in the parameter findings except pH of PKG 7.00, 9.91 and 9.46 in the vessels such as copper, iron and mud pot respectively. The particle size of Kshara was in between 429.7 to 667 nm under 15.00KV magnification 7.5 KX and EDAX report of Phalasha Kshara under 400 μm potassium Wt% 40.05 and Oxygen is Wt% 39.12. Under 50 μm potassium Wt% 48.91 and Oxygen Wt% 33.40. Under 70 μm potassium Wt% 27.90 and Oxygen Wt% 37.78. As per this study copper vesse l is found better for PKG than Iron and Mud pot for assessment of end process and also on analytical parameter.


2020 ◽  
Vol 5 (06) ◽  
pp. 64-72
Author(s):  
Shivappa A. Gangal ◽  
Deepa S. Gangal

Beauty is either skin deep i.e. Superficial or the purity of soul itself the later which is implied to Satwa Guna is penultimate and is beyond physical afflictions. Complexion, color etc. attributed to the healthy status of Tawk (skin) and the humors and the former is mean of sensory perception and the Vata Dosha pervades in it. People who live in urban areas and in climates with low humidity seen to be at increased risk for developing atopic dermatitis. W.H.O reveals that more than 75 million people all over the world have this disease.


2020 ◽  
Vol 5 (06) ◽  
pp. 73-81
Author(s):  
Ruchika Dighekar ◽  
Kiran Tawalare

Ayurvedic medicine is a system of traditional medicine native to India. Ayurveda is based on peculiar fundamental principles like Shatpadarth, Tridosha Theory, Panchamahabhuta Theory, Prakriti, Ojas, Dhatu, Mala, Agni, Manas, and Atma etc. The concepts of Ayurveda are expressed with Gunas. The increased elements are treated by opposite Guna. In support of the above concept, an experimental study on the 3T3-L1 cell line is carried out for examine the adipocytic and anti adipocytic activity of Snigdha and Ruksha Guna respectively. The results were assessed with the help of evaluation of sublethal concentration by using XTT assay and lipid assay. The aim of basic research in Ayurveda through bioscience is to explore scientific innovation and opportunities in fundamental concept of Ayurveda. Fundamental research needs to be done to highlight the concept of gurvadi guna through the in vitro study.


2020 ◽  
Vol 5 (06) ◽  
pp. 82-86
Author(s):  
Abhilasha Bhawalkar ◽  
Shreya Gulati ◽  
Sanjyot Mulay ◽  
Rajesh Shetty

Major objective of root canal treatment is disinfection of the root canal system and elimination of microbiota. Various intracanal medicaments as an adjunct to mechanical disinection and irrigation have been used but due to the harmful effects of the commercially available agents, a need for natural alternatives is felt over the time. This in-vitro study aims to evaluate the antibacterial effectiveness of natural agents Septillin and Aloe vera with Calcium hydroxide and without Calcium hydroxide on the Streptococcus mitis, E. Faecalis and Candida albicans using agar well diffusion method. The antibacterial activity was assessed by the diameter of zone of inhibition seen as clear zone around the wells. The study showed that Septillin in combination with Calcium hydroxide and alone showed considerable antimicrobial activity against Streptococcus mitis, Enterococcus faecalis and Candida albicans where as Aloe vera with Calcium hydroxide showed to be mildly effective against all three but not as effective as Septillin and Calcium hydroxide when tested alone.


2020 ◽  
Vol 5 (06) ◽  
pp. 120-129
Author(s):  
Bargale Sushant Sukumar ◽  
Tripathy T. B. ◽  
Shashirekha H.K.

Introduction: The present article deals with study of phytochemical analysis of Withania somnifera Dunal roots. Ashwagandha (Withania somnifera Dunal - Solanaceae), The use of Ashwagandha (WS) is increasing due to a number of chemical constituents present in are found useful for promotion of health. Important bio-active constituents of Ashwagandha root powder are alkaloids, tannins and flavonoid and phenolic compound helps to promote the health benefits. Objective: Evolution of Physico- chemical and phyto chemical analysis of Ashwagandha (WS) powder. Materials and methods: The current investigation deals with extraction and detection or screening of active phytochemical compounds from different extracts of Withania somnifera root. Pharmacognostic studies, Physico-chemical studies, Preliminary phytochemical studies and HPTLC was carried out. Result and conclusion: The result drown were 2% foreign mater was determined. Loss on drying 1.6%, total ash obtained was 9%, acid insoluble ash was 1% and water soluble extractive was 12% and Alcohol soluble extractive was 13%. The phytochemical investigation revealed the presence of various phytochemical constituents such as alkaloids, flavonoids, carbohydrate, Steroids and Saponin Glycoside. HPTLC chromatograms of methanol extracts obtained from root of Withania somnifera revealed that higher quality of with a nolides was present. Hence the root of Withania somnifera was considered to mostly prefer for commercial preparation of drugs.


2020 ◽  
Vol 5 (06) ◽  
pp. 109-115
Author(s):  
Ganapathi Rao I ◽  
Chandrakanth M. Halli ◽  
Subhod Kamthikar

Standardization of herbal drugs is essential to certify their quality and purity. Kshara (alkaline substance) of Palasha (Butea monosperma) is an important constituent in many Ayurvedic formulations, but its standard manufacturing process (SMP) is not attempted till date. This study is aimed to establish SMP for Palashakshara. In pharmaceutical process; generally, the sediments of ash obtained at the end of washes will be discarded. However, in the study, we attempted to wash the sediments repeatedly by adding water to extract more Kshara. Palasha was collected from the local area and authenticated. Kshara was prepared by following standard methods and the preliminary physicochemical profile was developed. It is observed that the ash yields Kshara even in the consecutive washes. First wash yielded 21.23% w/w Kshara, while the second and third washes yielded 9.38% w/w and 4.76% w/w, respectively. Repeated washes yield more Kshara. Hence, it is advocated to wash the ashes repeatedly. As the findings are encouraging, similar experiments can be extended to all other Kshara preparations.


2020 ◽  
Vol 5 (06) ◽  
pp. 87-90
Author(s):  
Amar Baliram Abhrange ◽  
Archana Amar Abhrange ◽  
Sachin S. Waghmare

The growth and existence of the human body is dependent on these seven Dhatus. These seven Dhatus are composed of five elements or Panchmahabhutas. Dhatu Sarata or Tissue excellence is a quality assessment of seven Dhatu. Examination of Dhatu Sarata is done at physical and psychological level. For determining the Dhatu Sarata, when the positive features are present above 75 %, it will be considered as best tissue quality (Uttam Sarata). When the positive features are present between 75 % and 25 %, it will be considered as moderate tissue quality (Madhyam Sarata). When positive features are present below 25 %, it will be labeled as poor tissue quality (Heen Sarata). The bodily movements which are meant for producing firmness and strength in the body are known as Vyayama or physical exercises. „Dehabala’ (Physical fitness) of subjects will be determined by Harvard step test. “Harvard Step Test” is a practical application of Ayurvedic Principal that “Bala should be measured by Vyamshakti” (Balam Vyayamshakty Parikshet). The person should be examined with reference to his capacity for exercise which is determined by one‟s ability to perform work. Therefore this study will estimate Dehabala and study the Dhatusarata and their association between them.


2020 ◽  
Vol 5 (06) ◽  
pp. 98-101
Author(s):  
Sreelakshmi A ◽  
Shrinidhi R ◽  
Sudhakar Bhat ◽  
Sreejith K ◽  
Chaithra S. Hebbar

Background: Vatsanabha is a potent cardiac poison comes under the category of Mahavisha with its main active principles aconitine, picraconine and pseudaconine. In the literatures there are descriptions about toxicants and in some traditional Malayalam textbooks antidotes has been explained under the concept “Prathyoushadha”. Neeli Moola has been mentioned as a Prathyoushadha for Vatsanabha poisoning in a renowned textbook „Visha Vaidya Jyotsnika‟. Hence to evaluate the antidotal activity in Vatsanabha poisoning, Neeli Moola Kalka has been used and the haematological parameters were analyzed to screen the results. Methods: Wistar strain albino rats were used in this study which were divided into 3 groups, normal control, toxic control and the test drug group. The duration of the study was 28 days .The data generated was mentioned as Mean±SEM. Difference among the groups was assessed by employing one way ANOVA followed by Dunnet‟s mul tiple „t‟ test. Results: Reversible action has been observed after the administration of Neeli Moola Kalka in the hematological parameters which has shown toxicity changes due to administration of Vatsanabha. Conclusion: Neeli Moola Kalka is having mild to moderate antidote effect in Vatsanbha induced toxicity.


2020 ◽  
Vol 5 (06) ◽  
pp. 51-57
Author(s):  
Varsha Mohan ◽  
Sreeni T.V. ◽  
Jacob M. Titus

Benign Prostatic Hyperplasia (BPH) is the adenomatous hyperplasia of the periurethral part of the prostate gland that occurs especially in men over 50 years old and that tends to obstruct urination by constricting the urethra. Overall nearly 80% of men will develop BPH, and as many as 30% will receive treatment for it. The present study was a clinical validation and standardization of Ayurvedic medicines which can provide an improved response to the disease as the present conventional practices are not satisfactory. The study design was interventional. Twenty patients satisfying the selection criteria were selected from the OPD of Government Ayurveda College, Trivandrum. 125 mg of Swarnamakshika and Yavakshara were advised to take with Madhu, followed by 48 ml of Varanadikashaya for a period of 45 days. Assessments were done before and after the study using assessment criteria. The study was statistically significant in symptomatic relief. The study therefore concludes that the combination is effective in the management of BPH.


2020 ◽  
Vol 5 (06) ◽  
pp. 43-50
Author(s):  
M. Ramadas ◽  
Padmanabha Rugvedi ◽  
Pankaj Kumar Gupta ◽  
Rajiva Kumar Rai ◽  
JLN Sastry

Context: Functional constipation which has no underlying organic causes is difficult to be allopathic treatment for long term due to its side effects and undeniable effect, thus a natural balanced and compatible formulation needs to be validated. Objectives: Current study aimed to assess a poly-herbal formulation in management of functional constipation. Material and Methods: This study was 28 days, two armed, randomized, open labeled, prospective clinical study. 60 clinically confirmed cases of functional constipation patients randomized to receive orally either 2 teaspoonful of PP/JLN/107/09-10 Syrup or 1 teaspoonful of 5- 6 gm of Isabgol powder. Results were analyzed as per Rome II criteria and other associated symptoms like headache, acidity, belching, barborgysmy, flatulence and abdominal dis tension or bloating which are recorded on VAS score. Results: PP/JLN/107/09-10 scored over Isabgol on four out of six parameters of Rome II Criteria viz., frequency of bowel movement, straining at defecation, lumpy I har dstool formation, feeling of incomplete evacuation, feeling of ano-rectal blockage and manual maneuvers (p less than 0.001). Trial drugs showed comparable effects (p > 0.05) in reducing the mean scores of associated symptoms like headache, acidity, belching, borgorgysmy, flatulence and abdominal distension. However, trial drug was found to perform statistically significant result in more number of parameters in comparison to Isabgol. Conclusion: PP/JLN/107/09-10 was found to be effective and safe in reliving functional constipation.


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