scholarly journals Skin Microbiota Content in Children and its Effect on Acne Pathogenesis

2021 ◽  
Vol 20 (5) ◽  
pp. 430-434
Author(s):  
Larisa S. Kruglova ◽  
Natalia V. Gryazeva ◽  
Anait V. Tamrazova

Acne is a common chronic inflammatory skin disease in adolescence. The involvement of cosmetically important zones inevitably leads to decrease in our patients' quality of life. This review considers modern methods of skin microbiota analysis, describes the microorganisms' composition in newborns and its changes during growing-up. Cutibacterium acnes (that dominates in the microbiota of skin areas with sebaceous glands) role in acne pathogenesis is described.

2021 ◽  
Vol 22 (11) ◽  
pp. 6078
Author(s):  
Jiun-Wen Guo ◽  
Shiou-Hwa Jee

Skin barrier functions, environmental insults, and genetic backgrounds are intricately linked and form the basis of common inflammatory skin disorders, such as atopic dermatitis, psoriasis, and seborrheic dermatitis, which may seriously affect one’s quality of life. Topical therapy is usually the first line of management. It is believed that successful topical treatment requires pharmaceutical formulation from a sufficient dosage to exert therapeutic effects by penetrating the stratum corneum and then diffusing to the target area. However, many factors can affect this process including the physicochemical properties of the active compound, the composition of the formulation base, and the limitations and conditions of the skin barrier, especially in inflammatory skin. This article briefly reviews the available data on these issues and provides opinions on strategies to develop a suitable formulation for inflammatory skin disease treatment.


1997 ◽  
Vol 22 (03) ◽  
pp. 128-133
Author(s):  
A.J. HARRIS ◽  
D. DEAN ◽  
S. BURGE ◽  
F. WOJNAROWSKA

2021 ◽  
Vol 46 (5) ◽  
pp. 100799
Author(s):  
David A. Bulger ◽  
Sheharyar Minhas ◽  
Abdul Aziz Asbeutah ◽  
Sharif Kayali ◽  
Hamid A.K. Shirwany ◽  
...  

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