Sildenafil for pulmonary hypertension complicating bronchopulmonary dysplasia

2014 ◽  
Vol 7 (4) ◽  
pp. 393-395 ◽  
Author(s):  
Varsha Bhatt-Mehta ◽  
Steven M Donn
2019 ◽  
Vol 97 (3) ◽  
pp. 197-205 ◽  
Author(s):  
Mark A. Underwood ◽  
Stephen Wedgwood ◽  
Satyan Lakshminrusimha ◽  
Robin H. Steinhorn

In the premature infant, poor growth in utero (fetal growth restriction) and in the first weeks of life (postnatal growth restriction) are associated with increased risk for bronchopulmonary dysplasia and pulmonary hypertension. In this review, we summarize the epidemiologic data supporting these associations, present a novel rodent model of postnatal growth restriction, and review 5 promising mechanisms by which poor nutrition may affect the developing lung. These observations support the hypothesis that nutritional and (or) pharmacologic interventions early in life may be able to decrease risk of the pulmonary complications of extreme prematurity.


2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Aaron Kleinertz ◽  
Robert Conhaim ◽  
Taylor Shuster ◽  
Sidney Mahan ◽  
Marlowe Eldridge ◽  
...  

2019 ◽  
Vol 39 (9) ◽  
pp. 1282-1290
Author(s):  
Alvin Singh ◽  
Brian Feingold ◽  
Belinda Rivera-Lebron ◽  
Daniel Weiner ◽  
Stacey Drant

2017 ◽  
Vol 188 ◽  
pp. 24-34.e1 ◽  
Author(s):  
Usha Krishnan ◽  
Jeffrey A. Feinstein ◽  
Ian Adatia ◽  
Eric D. Austin ◽  
Mary P. Mullen ◽  
...  

Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 359
Author(s):  
Das ◽  
Jadotte ◽  
Chan

Pulmonary hypertension (PH) is a complication of bronchopulmonary dysplasia (BPD). The underlying pathophysiology of BPD-associated PH is complex and poorly understood. Echocardiogram may underestimate the severity of pulmonary hypertensive vascular disease in severe BPD. Digital subtraction pulmonary angiography (DSPA) is a potentially useful imaging modality for evaluating changes in the pulmonary vasculature of BPD-associated PH. In this study, we objectively quantified the pulmonary hypertensive vascular changes demonstrated by DSPA using a novel pulmonary vascular underperfusion score (PVUS) and correlated the scoring system with echocardiography parameters and cardiac hemodynamics by right heart catheterization.


2020 ◽  
Vol 40 (11) ◽  
pp. 1726-1728
Author(s):  
Audrey Hébert ◽  
Christine Drolet ◽  
Gabriel Altit ◽  
Andréanne Villeneuve ◽  
Anie Lapointe ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document