Hyperinsulinemia and risk for hepatocellular carcinoma in patients with chronic liver diseases and Type 2 diabetes mellitus

2009 ◽  
Vol 3 (5) ◽  
pp. 465-467 ◽  
Author(s):  
Valter Donadon ◽  
Massimiliano Balbi ◽  
Giorgio Zanette
2019 ◽  
Vol 8 (6) ◽  
pp. 3206-3215 ◽  
Author(s):  
Chen‐Pin Wang ◽  
John Kuhn ◽  
Dimpy P. Shah ◽  
Susanne Schmidt ◽  
Yui‐Wing F. Lam ◽  
...  

2010 ◽  
Vol 2 (1) ◽  
pp. 81-84 ◽  
Author(s):  
NAOTA TAURA ◽  
TATSUKI ICHIKAWA ◽  
HISAMITSU MIYAAKI ◽  
HIROSHI YATSUHASHI ◽  
HIROMI ISHIBASHI ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Hamed Ebrahimzadeh Leylabadlo ◽  
Hossein Samadi Kafil ◽  
Safar Farajnia ◽  
Dariush Shanehbandi ◽  
Seyed Yaghoub Moaddab ◽  
...  

2016 ◽  
Vol 64 (6) ◽  
pp. 1358-1364 ◽  
Author(s):  
Sarah H. Wild ◽  
Joanne R. Morling ◽  
David A. McAllister ◽  
Jan Kerssens ◽  
Colin Fischbacher ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-7
Author(s):  
Lingling He ◽  
Shuan Zhang ◽  
Xiaoli Liu ◽  
Yuyong Jiang ◽  
Xianbo Wang ◽  
...  

Aim. To establish a new score model to predict risk of death in patients with hepatocellular carcinoma and type 2 diabetes mellitus.Methods. This was a retrospective study of 147 patients with hepatocellular carcinoma and type 2 diabetes mellitus who came to Beijing Ditan Hospital between October 2008 and June 2013. Univariate and multivariate logistic regression analysis was performed to obtain the independent factors associated with death risk. A new score model was devised according to these factors.Results. A prediction score model composed of HbA1c, NLR, age, and CTP class was devised, which ranged from 0 to 7. AUROC of the score was 0.853 (P<0.001, 95% CI: 0.791–0.915). Scores 0–2, 3-4, and 5–7 identified patients as low-, medium-, and high-risk categories. The cumulative survival rate was 93.6%, 83.0%, and 74.5% in the low-risk group in 1, 2, and 3 years, while it was 64.0%, 46.0%, and 26.0% in the medium-risk group, whereas it was 24.0%, 12.0%, and 6.0% in the high-risk group, respectively. The cumulative survival rate was significantly higher in the low-risk group than that in the medium-risk group and high-risk group (P<0.001).Conclusion. The HbA1c-based score model can be used to predict death risk in patients with hepatocellular carcinoma and type 2 diabetes mellitus.


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