scholarly journals Expanding role of fractional flow reserve in the cardiac catheterization laboratory

2009 ◽  
Vol 7 (5) ◽  
pp. 447-449
Author(s):  
William F Fearon
2013 ◽  
Vol 1 (1) ◽  
pp. 50-53
Author(s):  
Ivan Simic ◽  
Vladimir Zdravkovic ◽  
Rada Vucic ◽  
Violeta Iric-Cupic ◽  
Goran Davidovic ◽  
...  

Background: Coronary artery disease is the most common cause of death in a modern world. This dictates the development a network of Catheterization laboratories without cardiosurgical capabilities.Aim: We postulate that the most valuable tool in the decision process on myocardial revascularization is fractional flow reserve (FFR), especially when we deal with borderline coronary lesions.Material and Methods: A total of 72 patients with 94 intermediate coronary stenosis (30%-70% diameter reduction) were included in this study. We tested FFR and angiography based decision model on myocardial revascularization.Results:  Mean FFR value on left anterior descending coronary artery (LAD) was lower than in others two arteries (p=0.017). FFR after percutaneous coronary intervention (PCI) was significantly better (p<0.0001). The decision for PCI predominates before FFR diagnostics, but after FFR the decision is quite opposite. There is a weak negative correlation between FFR and diameter of stenosis assessed by angiography (r= - 0.245 p=0.038) and positive correlation between diameter of stenosis assessed by angiography and by quantitative coronary angiography (QCA) (r=0.406 p<0.0005).Conclusion:  Our results strongly suggest that FFR is necessary tool in centers without possibilities of heart team onsite consultation and that prevents numerous unnecessary PCI.


2019 ◽  
Vol 41 (34) ◽  
pp. 3271-3279 ◽  
Author(s):  
Shengxian Tu ◽  
Jelmer Westra ◽  
Julien Adjedj ◽  
Daixin Ding ◽  
Fuyou Liang ◽  
...  

Abstract Fractional flow reserve (FFR) and instantaneous wave-free ratio are the present standard diagnostic methods for invasive assessment of the functional significance of epicardial coronary stenosis. Despite the overall trend towards more physiology-guided revascularization, there remains a gap between guideline recommendations and the clinical adoption of functional evaluation of stenosis severity. A number of image-based approaches have been proposed to compute FFR without the use of pressure wire and induced hyperaemia. In order to better understand these emerging technologies, we sought to highlight the principles, diagnostic performance, clinical applications, practical aspects, and current challenges of computational physiology in the catheterization laboratory. Computational FFR has the potential to expand and facilitate the use of physiology for diagnosis, procedural guidance, and evaluation of therapies, with anticipated impact on resource utilization and patient outcomes.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Caroline Ball ◽  
Gianluca Pontone ◽  
Mark Rabbat

Fractional flow reserve (FFR) derived from coronary CTA datasets (FFRCT) is a major advance in cardiovascular imaging that provides critical information to the Heart Team without exposing the patient to excessive risk. Previously, invasive FFR measurements obtained during a cardiac catheterization have been demonstrated to reduce contrast use, number of stents, and cost of care and improve outcomes. However, there are barriers to routine use of FFR in the cardiac catheterization suite. FFRCT values are obtained using resting 3D coronary CTA images using computational fluid dynamics. Several multicenter clinical trials have demonstrated the diagnostic superiority of FFRCT over traditional coronary CTA for the diagnosis of functionally significant coronary artery disease. This review provides a background of FFR, technical aspects of FFRCT, clinical applications and interpretation of FFRCT values, clinical trial data, and future directions of the technology.


2015 ◽  
Vol 87 (9) ◽  
pp. 106 ◽  
Author(s):  
F. Yu. Kopylov ◽  
A. A. Bykova ◽  
Yu. V. Vasilevsky ◽  
S. S. Simakov

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P3972-P3972
Author(s):  
Y. H. Lee ◽  
K. W. Seo ◽  
J. S. Park ◽  
H. M. Yang ◽  
B. J. Choi ◽  
...  

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