Assessment of Health-Related Quality of Life in Patients with Chronic Respiratory Failure.

Abstract Background: One of the major challenges of the present century is chronic respiratory failure with a complex, chronic, disabling, and progressive nature, which can gradually affect patient health-related quality of life and their individual and social activities. Therefore, studying its concept will help in recognizing changes in the disease process and predict the status of the disease. This study was prepared to determine health-related quality of life of patients with chronic respiratory failure using a mixed-method approach.Methods and Analysis: The mixed-method approach, with a convergent parallel design, will be used to conduct the research in which the quantitative and qualitative study is performed simultaneously and with the same weight. In the quantitative study section, a cultural and psychometric adaptation of the Severe Respiratory Insufficiency Questionnaire is first translated for patients with severe respiratory failure and then the health-related quality of life dimensions of patients with chronic respiratory failure will be measured using a questionnaire pertaining to the culture of Iranian society in a descriptive-analytical study. Simultaneously with the quantitative study, the researcher will use a qualitative study to explain the perception of patients with chronic respiratory failure and health-related quality of life. Finally, the results of a quantitative study obtained from the analysis of descriptive statistics data (mean and standard deviation) and inferential statistics (analysis of variance, t-test, and regression) are integrated by SPSS software version 18. The results of a qualitative study are the results of conventional content analysis, by comparison and confrontation during interpretation.Discussion & Conclusion: Due to the complexity of the research and for gaining in-depth understanding into the health-related quality of life of patients with chronic respiratory failure, this article will be based on a combination of quantitative and qualitative data. In this research, quantitative and qualitative methods overlap and add to the richness of the data so that the results, beyond the numbers and figures of a quantitative study, will be congruent with an explanation of the concept in a qualitative study and will be discussed and interpreted.

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Comparison of Two Questionnaires CAT and MRF-26 to Assess the Effect of Pulmonary Rehabilitation on Health Related Quality of Life in COPD Patients With Chronic Respiratory Failure

CHEST Journal ◽

10.1016/j.chest.2016.02.512 ◽

2016 ◽

Vol 149 (4) ◽

pp. A491

Author(s):

Francesca Gibellino ◽

Laura Mammana ◽

Annalisa Rodo

Keyword(s):

Quality Of Life ◽

Respiratory Failure ◽

Pulmonary Rehabilitation ◽

Chronic Respiratory Failure ◽

Health Related Quality ◽

Copd Patients ◽

Related Quality ◽

Health Related

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Comparison of Different Disease-Specific Health-Related Quality of Life Measurements in Patients with Long-Term Noninvasive Ventilation

Canadian Respiratory Journal ◽

10.1155/2017/8295079 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 6

Author(s):

Toru Oga ◽

Hiroyuki Taniguchi ◽

Hideo Kita ◽

Tomomasa Tsuboi ◽

Keisuke Tomii ◽

...

Keyword(s):

Quality Of Life ◽

Respiratory Failure ◽

Pulmonary Function ◽

Psychological Status ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Disease Specific

Background. Two disease-specific questionnaires have been developed to assess health-related quality of life (HRQL) in patients with chronic respiratory failure: the Severe Respiratory Insufficiency (SRI) Questionnaire and the Maugeri Respiratory Failure (MRF) Questionnaire. We aimed to compare the characteristics of the SRI, MRF-26, and St. George’s Respiratory Questionnaire (SGRQ) for use in patients with home noninvasive ventilation (NIV). Methods. Fifty-six outpatients receiving long-term NIV were recruited and underwent assessments of pulmonary function, arterial blood gas, HRQL, dyspnea, and psychological status. Results. Correlations of the SRI and MRF-26 with the SGRQ were modest. While pulmonary function was weakly related to only some domains of the SRI and MRF-26, the modified Medical Research Council (mMRC) dyspnea scale and Hospital Anxiety and Depression Scale (HADS) were significantly related to all domains of the SRI and MRF-26. Multiple regression analyses showed that HADS depression and mMRC accounted for 34% and 27% of the variance in the SRI, 24% and 37% in the MRF-26, and 17% and 46% in the SGRQ, respectively. Conclusions. The SRI and MRF-26 were reliable questionnaires for patients receiving long-term NIV. Dyspnea and psychological status were their main common determinants. The SRI covers more psychological health impairments than the MRF. This trial is registered with ClinicalTrials.gov Identifier: NCT00905476.

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Analysis of Optimal Health-Related Quality of Life Measures in Patients Waitlisted for Lung Transplantation

Canadian Respiratory Journal ◽

10.1155/2020/4912920 ◽

2020 ◽

Vol 2020 ◽

pp. 1-9 ◽

Cited By ~ 1

Author(s):

Junko Tokuno ◽

Toyofumi F Chen-Yoshikawa ◽

Toru Oga ◽

Takahiro Oto ◽

Tomoyo Okawa ◽

...

Keyword(s):

Quality Of Life ◽

Respiratory Failure ◽

Lung Transplantation ◽

Psychological Status ◽

Health Related Quality ◽

Score Distribution ◽

Patient Reported ◽

Related Quality ◽

Health Related

Background. Improving health-related quality of life (HRQL) is an important goal of lung transplantation, and St. George’s Respiratory Questionnaire (SGRQ) is frequently used for assessing HRQL in patients waitlisted for lung transplantation. We hypothesized that chronic respiratory failure (CRF)-specific HRQL measures would be more suitable than the SGRQ, considering the underlying disease and its severity in these patients. Methods. We prospectively collected physiological and patient-reported data (HRQL, dyspnea, and psychological status) of 199 patients newly registered in the waiting list of lung transplantation. CRF-specific HRQL measures of the Maugeri Respiratory Failure Questionnaire (MRF) and Severe Respiratory Insufficiency Questionnaire (SRI) were assessed in addition to the SGRQ. Results. Compared to the MRF-26 and SRI, the score distribution of the SGRQ was skewed toward the worse ends of the scale. All domains of the MRF-26 and SRI were significantly correlated with the SGRQ. Multiple regression analyses to investigate factors predicting each HRQL score indicated that dyspnea and psychological status accounted for 12% to 28% of the variance more significantly than physiological measures did. The MRF-26 Total and SRI Summary significantly worsened from the baseline to 1 year (p<0.001 and p=0.010, respectively) in 103 patients who underwent a follow-up assessment without lung transplantation, while the SGRQ showed a marginal significant worsening (p=0.040). Conclusions. The MRF-26 and SRI are valid, discriminative, and responsive in patients waitlisted for lung transplantation. In terms of the score distribution and responsiveness, CRF-specific measures may function better in their HRQL assessment than the currently used measures do.

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