scholarly journals Use of PET/CT to aid clinical decision-making in cases of solitary pulmonary nodule: a probabilistic approach

2020 ◽  
Vol 53 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Felipe Alves Mourato ◽  
Ana Emília Teixeira Brito ◽  
Monique Sampaio Cruz Romão ◽  
Renata Guerra Galvão Santos ◽  
Cristiana Altino de Almeida ◽  
...  
Keyword(s):  
Pulmonary Nodule ◽  
Fdg Pet ◽  
Clinical Decision Making ◽  
Solitary Pulmonary Nodule ◽  
Probabilistic Approach ◽  
Solitary Pulmonary Nodules ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Abstract Objective: To determine the frequency with which 18F-FDG-PET/CT findings change the probability of malignancy classification of solitary pulmonary nodules. Materials and Methods: This was a retrospective analysis of all 18F-FDG-PET/CT examinations performed for the investigation of a solitary pulmonary nodule between May 2016 and May 2017. We reviewed medical records and PET/CT images to collect the data necessary to calculate the pre-test probability of malignancy using the Swensen model and the Herder model. The probability of malignancy was classified as low if < 5%, intermediate if 5-65%, and high if > 65%. Cases classified as intermediate in the Swensen model were reclassified by the Herder model. Results: We reviewed the records for 33 patients, of whom 17 (51.5%) were male. The mean age was 68.63 ± 12.20 years. According to the Swensen model, the probability of malignancy was intermediate in 23 cases (69.7%). Among those, the application of the Herder model resulted in the probability of malignancy being reclassified as low in 6 (26.1%) and as high in 8 (34.8%). Conclusion: 18F-FDG-PET/CT was able to modify the probability of malignancy classification of a solitary pulmonary nodule in more than 50% of the cases evaluated.

Subscapular fibrohistiocytoma: Casual finding in a 18F-FDG-PET/CT scan due to solitary pulmonary nodule

2010 ◽  
Vol 29 (2) ◽  
pp. 93-94
Author(s):  
J. Banzo ◽  
M.A. Ubieto ◽  
J. Velilla ◽  
E. Prats ◽  
P. Razola ◽  
...  
Keyword(s):  
Ct Scan ◽  
Pulmonary Nodule ◽  
Fdg Pet ◽  
Solitary Pulmonary Nodule ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Pet Ct Scan

scholarly journals Solitary pulmonary nodule and 18F-FDG PET/CT. Part 1: epidemiology, morphological evaluation and cancer probability

2016 ◽  
Vol 49 (1) ◽  
pp. 35-42 ◽  
Author(s):  
Marcos Pretto Mosmann ◽  
Marcelle Alves Borba ◽  
Francisco Pires Negromonte de Macedo ◽  
Adriano de Araujo Lima Liguori ◽  
Arthur Villarim Neto ◽  
...  
Keyword(s):  
Pulmonary Nodule ◽  
Solitary Pulmonary Nodule ◽  
Radiographic Finding ◽  
Pulmonary Nodules ◽  
Solitary Pulmonary Nodules ◽  
Benign Lesions ◽  
Morphological Evaluation ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Abstract Solitary pulmonary nodule corresponds to a common radiographic finding, which is frequently detected incidentally. The investigation of this entity remains complex, since characteristics of benign and malignant processes overlap in the differential diagnosis. Currently, many strategies are available to evaluate solitary pulmonary nodules with the main objective of characterizing benign lesions as best as possible, while avoiding to expose patients to the risks inherent to invasive methods, besides correctly detecting cases of lung cancer so as the potential curative treatment is not delayed. This first part of the study focuses on the epidemiology, the morfological evaluation and the methods to determine the likelihood of cancer in cases of indeterminate solitary pulmonary nodule.

scholarly journals Risk-related 18F-FDG PET/CT and new diagnostic strategies in patients with solitary pulmonary nodule: the ITALIAN multicenter trial

2018 ◽  
Vol 45 (11) ◽  
pp. 1908-1914 ◽  
Author(s):  
Marco Spadafora ◽  
Leonardo Pace ◽  
Laura Evangelista ◽  
Luigi Mansi ◽  
Francesco Del Prete ◽  
...  
Keyword(s):  
Pulmonary Nodule ◽  
Fdg Pet ◽  
Solitary Pulmonary Nodule ◽  
Multicenter Trial ◽  
Diagnostic Strategies ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Incremental Value of Integrated FDG-PET/CT in Evaluating Indeterminate Solitary Pulmonary Nodule for Malignancy

2009 ◽  
Vol 12 (2) ◽  
pp. 204-209 ◽  
Author(s):  
Chih-Yung Chang ◽  
Ching Tzao ◽  
Shih-Chun Lee ◽  
Cheng-Yi Cheng ◽  
Chang-Hsien Liu ◽  
...  
Keyword(s):  
Pulmonary Nodule ◽  
Fdg Pet ◽  
Solitary Pulmonary Nodule ◽  
Incremental Value ◽  
Pet Ct ◽  
Fdg Pet Ct

Diagnostic value of 18F-FDG-PET/CT for the evaluation of solitary pulmonary nodules

2017 ◽  
Vol 38 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Zong Ruilong ◽  
Xie Daohai ◽  
Geng Li ◽  
Wang Xiaohong ◽  
Wang Chunjie ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Pulmonary Nodules ◽  
Diagnostic Value ◽  
Solitary Pulmonary Nodules ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

The role of 18F-FDG PET or 18F-FDG-PET/CT in the evaluation of solitary pulmonary nodules

2015 ◽  
Vol 84 (10) ◽  
pp. 2032-2037 ◽  
Author(s):  
Wenbo Li ◽  
Hua Pang ◽  
Qiong Liu ◽  
Jing Zhou
Keyword(s):  
Fdg Pet ◽  
Pulmonary Nodules ◽  
Solitary Pulmonary Nodules ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Cardiovascular Mechanisms In Covid-19: Methodology of A Prospective Observational Multimodality Imaging Study (COSMIC-19 study)

2020 ◽  
Author(s):  
Shirjel Alam ◽  
Anoop Shah ◽  
Kevin Onyinkwa ◽  
Edward Nganga ◽  
Samuel Gitau ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Fdg Pet ◽  
Clinical Decision Making ◽  
Multimodality Imaging ◽  
Cardiac Injury ◽  
Imaging Study ◽  
Clinical Decision ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Abstract Background: 8-28% of patients infected with COVID-19 have evidence of cardiac injury, and this is associated with an adverse prognosis. The cardiovascular mechanisms of injury are poorly understood and speculative. We aim to use multimodality cardiac imaging including cardiac magnetic resonance (CMR) imaging, computed tomography coronary angiography (CTCA) and positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro- D-glucose integrated with computed tomography (18F-FDG-PET/CT) to identify the cardiac pathophysiological mechanisms related to COVID-19 infections.Methods: This is a single-centre exploratory observational study aiming to recruit 50 patients with COVID-19 infection who will undergo cardiac biomarker sampling. Of these, 30 patients will undergo combined CTCA & 18F-FDG-PET/CT, followed by CMR. Prevalence of obstructive and non-obstructive atherosclerotic coronary disease will be assessed using CTCA. CMR will be used to identify and characterise myocardial disease including presence of cardiac dysfunction, myocardial fibrosis, myocardial oedema and myocardial infarction. 18F-FDG-PET/CT will identify vascular and cardiac inflammation. Primary endpoint will be the presence of cardiovascular pathology and the association with troponin levels.Discussion: The results of the study will identify the presence and modality of cardiac injury associated COVID-19 infection, and the utility of multi-modality imaging in diagnosing such injury. This will further inform clinical decision making during the pandemic.TRIAL REGISTRATION: This study has been retrospectively registered at the ISRCTN registry (ID ISRCTN12154994) on 14th August 2020. Accessible at www.isrctn.com/ISRCTN12154994

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