Bacterial coinfections during murine cutaneous leishmaniasis

2020 ◽  
Author(s):  
Tiffany Yue-Fei Borbon
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Murine Cutaneous Leishmaniasis

Parasite killing by an effector monocyte subset during murine cutaneous Leishmaniasis

Cytokine ◽  
2009 ◽  
Vol 48 (1-2) ◽  
pp. 65
Author(s):  
Ricardo Goncalves ◽  
Xia Zhang ◽  
David M. Mosser
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Monocyte Subset ◽  
Murine Cutaneous Leishmaniasis

scholarly journals Interleukin-4 but not gamma interferon production correlates with the severity of murine cutaneous leishmaniasis.

1993 ◽  
Vol 61 (8) ◽  
pp. 3459-3465 ◽  
Author(s):  
L Morris ◽  
A B Troutt ◽  
K S McLeod ◽  
A Kelso ◽  
E Handman ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Gamma Interferon ◽  
Interleukin 4 ◽  
Interferon Production ◽  
Murine Cutaneous Leishmaniasis

scholarly journals The role of the P2X7 receptor in murine cutaneous leishmaniasis: aspects of inflammation and parasite control

2016 ◽  
Vol 13 (2) ◽  
pp. 143-152 ◽  
Author(s):  
Vanessa Ribeiro Figliuolo ◽  
Suzana Passos Chaves ◽  
Luiz Eduardo Baggio Savio ◽  
Maria Luiza Prates Thorstenberg ◽  
Érika Machado Salles ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
P2x7 Receptor ◽  
Parasite Control ◽  
Murine Cutaneous Leishmaniasis

Immunogenicity and efficacy of a bivalent DNA vaccine containing LeIF and TSA genes against murine cutaneous leishmaniasis

Apmis ◽  
2017 ◽  
Vol 125 (3) ◽  
pp. 249-258 ◽  
Author(s):  
Nahid Maspi ◽  
Fatemeh Ghaffarifar ◽  
Zohreh Sharifi ◽  
Abdolhossein Dalimi ◽  
Mohammad Saaid Dayer
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Dna Vaccine ◽  
Murine Cutaneous Leishmaniasis

Tissue eosinophilia and Leishmania mexicana mexicana eosinophil interactions in murine cutaneous leishmaniasis

1984 ◽  
Vol 6 (5) ◽  
pp. 397-408 ◽  
Author(s):  
G. GRIMALDI JR ◽  
M. J. SOARES ◽  
PAMELA L. MORIEARTY
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Mexicana ◽  
Tissue Eosinophilia ◽  
Murine Cutaneous Leishmaniasis

A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major

Vaccine ◽  
2001 ◽  
Vol 19 (25-26) ◽  
pp. 3369-3375 ◽  
Author(s):  
Sima Rafati ◽  
Ali-Hatef Salmanian ◽  
Tahere Taheri ◽  
Manije Vafa ◽  
Nicolas Fasel
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Major ◽  
Cysteine Proteinases ◽  
Dna Encoding ◽  
Murine Cutaneous Leishmaniasis

scholarly journals Subcutaneous immunization against Leishmania major - infection in mice: efficacy of formalin-killed promastigotes combined with adjuvants

2010 ◽  
Vol 52 (2) ◽  
pp. 95-100 ◽  
Author(s):  
Joshua M. Mutiso ◽  
John C. Macharia ◽  
Rosemary M. Mutisya ◽  
Evans Taracha
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Major ◽  
Immune Status ◽  
Parasite Burden ◽  
Interferon Γ ◽  
Cutaneous Lesions ◽  
Ifn Γ ◽  
Efficacious Vaccine ◽  
Subcutaneous Immunization ◽  
Murine Cutaneous Leishmaniasis

Formalin-killed promastigotes (FKP) of Leishmania major, in combination with Montanide ISA 720 (MISA), BCG or alum were used in vaccination of an inbred murine model against cutaneous leishmaniasis (CL). Significant and specific increases in anti-FKP IgG responses were detected for both alum-FKP and BCG-FKP compared to MISA-FKP (p < 0.001). Significant increases in splenic lymphocyte recall proliferation was obtained in the MISA-FKP vaccinated mice compared to alum-FKP or BCG-FKP vaccinated groups (p < 0.01). The highest interferon-γ responses were observed in the BCG-FKP group followed by the MISA-FKP while the alum-FKP gave the least responses. Significantly reduced lesion sizes were obtained in the MISA-FKP group compared to the BCG/alum adjuvants-FKP vaccinated groups. Although the BCG-FKP group showed the highest IFN-γ responses, it failed to control cutaneous lesions. Significant reductions in parasite numbers were observed in the MISA-FKP and BCG-FKP vaccinated groups (p < 0.001). There was a good correlation between parasite burden and IFN-γ level indicating IFN-γ response as a sensitive parameter of the immune status. In conclusion, MISA-FKP is the most efficacious vaccine formulation against murine cutaneous leishmaniasis.

scholarly journals An Anti-Inflammatory Role for NLRP10 in Murine Cutaneous Leishmaniasis

2017 ◽  
Vol 199 (8) ◽  
pp. 2823-2833 ◽  
Author(s):  
Gwendolyn M. Clay ◽  
Diogo G. Valadares ◽  
Joel W. Graff ◽  
Tyler K. Ulland ◽  
Richard E. Davis ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Anti Inflammatory ◽  
Murine Cutaneous Leishmaniasis
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