Steven-Johnson Syndrome (SJS) in a Multiple Myeloma patient treated with lenalidomide and low dose dexamethasone regimen: a rare Case Report

2015 ◽  
Vol 3 (3) ◽  
pp. 353-355
Author(s):  
Dr Lohit kumar Kalita ◽  
◽  
Dr Chayanika Kalita ◽  
Dr Pabitra Kamar Gogoi ◽  
Dr Umesh Ch. Sarma ◽  
...  
2012 ◽  
Vol 138 (suppl 2) ◽  
pp. A330-A330
Author(s):  
Rajib Gupta ◽  
Dan Ketterer ◽  
Michael Gelfand ◽  
Vickie Baselski

2015 ◽  
Vol 6 (6) ◽  
pp. 278 ◽  
Author(s):  
Rajan Rajput ◽  
Shitalkumar Sagari ◽  
Astha Durgavanshi ◽  
Alpana Kanwar

2020 ◽  
Vol 26 (6) ◽  
pp. 1499-1500
Author(s):  
Hikmettullah Batgi ◽  
Mehmet Sinan Dal ◽  
Alparslan Merdin ◽  
Merih Kızıl Çakar ◽  
Tuğçe Nur Yiğenoğlu ◽  
...  

Introduction Multiple myeloma is a malignant neoplasm of plasma cells. Lenalidomide-dexamethasone treatment is a common treatment regimen used in refractory multiple myeloma. Case report We describe the case of a 58-year-old male multiple myeloma patient with a history of relapse after six months of autologous stem cell transplantation. The patient had nausea and bloody diarrhea developed during lenalidomide treatment. Management and outcome: Computed tomography showed diffuse marked edematous thickness in the wall of colonic, hepatic and splenic flexure, transverse colon, descending colon and sigmoid colon. Colonoscopic observation revealed highly granular, hyperemic and fragile mucosa. Colon biopsy was consistent with ischemic colitis. Lenalidomide treatment was discontinued. One month later, colon findings were detected as normalized through a colonoscopy. Discussion Risk of developing ischemic colitis should be kept in mind in patients receiving lenalidomide which should be discontinued in cases with severe bloody diarrhea of unknown origin.


2011 ◽  
Vol 40 (8) ◽  
pp. 513-518 ◽  
Author(s):  
S Ghosh ◽  
P Wadhwa ◽  
A Kumar ◽  
KM Pai ◽  
S Seshadri ◽  
...  

2021 ◽  
Vol 5 ◽  
pp. AB228-AB228
Author(s):  
Waris Ali Shah ◽  
Zeeshan Razzaq ◽  
Hamid Mustafa ◽  
Sarah Lungley ◽  
Mohammed Daoud ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Iuliana Vaxman ◽  
John Eaton ◽  
Hee Eun Lee ◽  
Morie A. Gertz

Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection. The patient recovered after treatment with corticosteroids, resumption of mycophenolate mofetil, and cessation of lenalidomide. Lenalidomide-associated allograft rejection has been reported in other organs. However, this is the first case report of liver rejection induced by lenalidomide.


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