scholarly journals Do the Changes of Event-Related Potentials and Frequency Band Responses to Sensory Stimuli Correlate to Age Cognitive Decline?

2017 ◽  
Vol 3 (1) ◽  
pp. 327-334 ◽  
Author(s):  
Juliana Dushanova ◽  
◽  
Mario Christov
Keyword(s):  
Cognitive Decline ◽  
Frequency Band ◽  
Event Related Potentials ◽  
Sensory Stimuli ◽  
Related Potentials

scholarly journals Risk and Resilience in an Acute Stress Paradigm: Evidence From Salivary Cortisol and Time-Frequency Analysis of the Reward Positivity

2020 ◽  
Vol 8 (5) ◽  
pp. 872-889 ◽  
Author(s):  
Paige Ethridge ◽  
Nida Ali ◽  
Sarah E. Racine ◽  
Jens C. Pruessner ◽  
Anna Weinberg
Keyword(s):  
Frequency Band ◽  
Acute Stress ◽  
Event Related Potentials ◽  
Risk And Resilience ◽  
Neural Responses ◽  
Time Frequency ◽  
Reward Positivity ◽  
Before And After ◽  
Related Potentials ◽  
Reward Responsivity

Both abnormal stress and reward responsivity are consistently linked to multiple forms of psychopathology; however, the nature of the associations between stress and reward sensitivity remains poorly understood. In the present study, we examined associations between the hypothalamic-pituitary-adrenal-axis stress response and event-related potentials sensitive to the receipt of reward-related feedback in a pre–post experimental paradigm. Neural responses were recorded while male participants completed a simple monetary-reward guessing task before and after the Montreal Imaging Stress Task. Results demonstrated that acute psychosocial stress significantly reduced the magnitude of neural responses to feedback in the reward-sensitive delta-frequency band but not the loss-sensitive theta-frequency band. In addition, a larger delta-frequency response to rewards at baseline predicted reduced overall cortisol response in the stress condition. These findings suggest, therefore, that neural reward circuitry may be associated with both risk for and resilience to stress-related psychopathology.

scholarly journals Taking into account latency, amplitude, and morphology: improved estimation of single-trial ERPs by wavelet filtering and multiple linear regression

2011 ◽  
Vol 106 (6) ◽  
pp. 3216-3229 ◽  
Author(s):  
L. Hu ◽  
M. Liang ◽  
A. Mouraux ◽  
R. G. Wise ◽  
Y. Hu ◽  
...  
Keyword(s):  
Linear Regression ◽  
Multiple Linear Regression ◽  
Pain Perception ◽  
Event Related Potentials ◽  
Relevant Information ◽  
Single Trial ◽  
Data Set ◽  
Wavelet Filtering ◽  
Sensory Stimuli ◽  
Related Potentials

Across-trial averaging is a widely used approach to enhance the signal-to-noise ratio (SNR) of event-related potentials (ERPs). However, across-trial variability of ERP latency and amplitude may contain physiologically relevant information that is lost by across-trial averaging. Hence, we aimed to develop a novel method that uses 1) wavelet filtering (WF) to enhance the SNR of ERPs and 2) a multiple linear regression with a dispersion term (MLRd) that takes into account shape distortions to estimate the single-trial latency and amplitude of ERP peaks. Using simulated ERP data sets containing different levels of noise, we provide evidence that, compared with other approaches, the proposed WF+MLRd method yields the most accurate estimate of single-trial ERP features. When applied to a real laser-evoked potential data set, the WF+MLRd approach provides reliable estimation of single-trial latency, amplitude, and morphology of ERPs and thereby allows performing meaningful correlations at single-trial level. We obtained three main findings. First, WF significantly enhances the SNR of single-trial ERPs. Second, MLRd effectively captures and measures the variability in the morphology of single-trial ERPs, thus providing an accurate and unbiased estimate of their peak latency and amplitude. Third, intensity of pain perception significantly correlates with the single-trial estimates of N2 and P2 amplitude. These results indicate that WF+MLRd can be used to explore the dynamics between different ERP features, behavioral variables, and other neuroimaging measures of brain activity, thus providing new insights into the functional significance of the different brain processes underlying the brain responses to sensory stimuli.

The role of event-related potentials in cognitive decline in Alzheimer’s disease

2010 ◽  
Vol 121 (2) ◽  
pp. 194-199 ◽  
Author(s):  
Chiou-Lian Lai ◽  
Ruey-Tay Lin ◽  
Li-Min Liou ◽  
Ching-Kuan Liu
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Event Related Potentials ◽  
Related Potentials

scholarly journals A Systematic Review of Cognitive Event-Related Potentials in mild cognitive impairment and Alzheimer’s disease

2020 ◽  
Author(s):  
Elizabeth R. Paitel ◽  
Marielle R. Samii ◽  
Kristy A Nielson
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Cognitive Processing ◽  
Event Related Potentials ◽  
Complex Tasks ◽  
Related Potentials

This systematic review examined whether event-related potentials (ERPs) during higher cognitive processing can detect subtle, early signs of neurodegenerative disease. Original, empirical studies retrieved from PsycINFO and PubMed were reviewed if they analyzed patterns in cognitive ERPs (150ms post-stimulus) differentiating mild cognitive impairment (MCI), Alzheimer’s disease (AD), or cognitively intact elders who carry AD risk through the Apolipoprotein-E ε4 allele (ε4+) from healthy older adult controls (HC). The 100 studies meeting inclusion criteria (MCI=47; AD=47; ε4+=6) analyzed N200, P300, N400, and occasionally, later components. While there was variability across studies, patterns of reduced amplitude and delayed latency were apparent in pathological aging, consistent with AD-related brain atrophy and cognitive impairment. These effects were particularly evident in advanced disease progression (i.e., AD > MCI) and in later ERP components measured during complex tasks. Although ERP studies in intact ε4+ elders are thus far scarce, a similar pattern of delayed latency was notable, along with a contrasting pattern of increased amplitude, consistent with compensatory neural activation. This limited work suggests ERPs might be able to index early neural changes indicative of future cognitive decline in otherwise healthy elders. As ERPs are also accessible and affordable relative to other neuroimaging methods, their addition to cognitive assessment might substantively enhance early identification and characterization of neural dysfunction, allowing opportunity for earlier differential diagnosis and targeting of intervention. To evaluate this possibility there is urgent need for well-powered studies assessing late cognitive ERPs during complex tasks, particularly in healthy elders at risk for cognitive decline.

scholarly journals Cognitive network interactions and beta 2 coherence in processing non-target stimuli in visual oddball task

2009 ◽  
pp. 139-148
Author(s):  
M Kukleta ◽  
M Brázdil ◽  
R Roman ◽  
P Bob ◽  
I Rektor
Keyword(s):  
Frequency Band ◽  
Intractable Epilepsy ◽  
Event Related Potentials ◽  
Stimulus Onset ◽  
Platinum Electrodes ◽  
Large Variability ◽  
Related Potentials ◽  
Beta 2 ◽  
Highly Correlated ◽  
Visual Oddball

Spatiotemporal dynamics of event-related potentials (ERP) evoked by non-target stimuli in a visual oddball experiment and the presence of coherent oscillations in beta 2 frequency band of decomposed EEG records from peristimulus period were investigated by means of intracranial electrodes in humans. Twenty-one patients with medically intractable epilepsy participated in the study. The EEG signal was recorded using platinum electrodes implanted in several cortical and subcortical sites. Averaged 2 s EEG records were analyzed. Task-specific EEG changes were found in each patient, ERPs were derived from 92 electrodes used (96 % of possible cases). In the majority of analysed cases, ERPs were composed of several distinct components, and their duration was mostly longer than 1 s. The mean onset of the first ERP component was 158±132 ms after the stimulus (median 112 ms, minimum value 42 ms, maximum value 755 ms), and large variability of these onset times was found in all the investigated structures. Possible coherence between neural activities of remote brain sites was investigated by calculating running correlations between pairs of decomposed EEG records (alpha, beta 1, beta 2 frequency bands were used, total number of correlated pairs was 662 in each frequency band). The record pairs exhibiting highly correlated time segments represented 23 % of all the investigated pairs in alpha band, 7 % in beta 1 band, and 59 % in beta 2 band. In investigated 2 s record windows, such segments were distributed evenly, i.e. they were also found before the stimulus onset. In conclusion, the results have implicated the idea that a lot of recorded ERPs was more or less by-products of chance in spreading a signal within the neuronal network, and that their functional relevance was somewhat linked with the phenomenon of activity synchronization.

P3-269: PROGNOSTIC VALUE OF EVENT-RELATED POTENTIALS FOR RATE OF COGNITIVE DECLINE IN PATIENTS WITH MILD ALZHEIMER'S DISEASE

2006 ◽  
Vol 14 (7S_Part_22) ◽  
pp. P1180-P1180
Author(s):  
Marco Cecchi ◽  
Carl H. Sadowsky ◽  
Diana Michalczuk ◽  
Elizabeth Vassey
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Prognostic Value ◽  
Event Related Potentials ◽  
Related Potentials
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