Synthesized sorbents based on silica with a pore structure of MCM-41, modified with amide groups. Using the low-temperature sorption of nitrogen, X-ray phase analysis (XRD), IR spectroscopy, and scanning electron microscopy, the textural and structural properties of the studied silica sorbents were determined. The kinetics of sorption of copper (II), nickel (II), cobalt (II) from aqueous solutions by the obtained reagents was studied, the dependence of the sorption ability of the reagents on the method of modifying the silica base and the monomer concentration during joint sorption of metals was determined. The possibility of separation of the investigated non-ferrous metals by the obtained reagents is shown.