scholarly journals The role of surgical sperm retrieval techniques in patients with azoospermia in assisted reproductive technology programs (literature review)

2018 ◽  
Vol 19 (3) ◽  
pp. 27-34
Author(s):  
S. I. Gamidov ◽  
A. Yu. Popova ◽  
N. G. Gasanov ◽  
R. I. Ovchinnikov ◽  
N. P. Naumov ◽  
...  
Keyword(s):  
Literature Review ◽  
Testicular Biopsy ◽  
Testicular Sperm Extraction ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Surgical Specimen ◽  
Intracytoplasmic Injection ◽  
Sperm Aspiration ◽  
Testicular Sperm Aspiration ◽  
Biological Parenthood

This literature review is dedicated to surgical sperm retrieval techniques, such as percutaneous and microsurgical epididymal sperm aspiration, testicular sperm aspiration, testicular sperm extraction (standard, microdissection, multifocal). Those methods allow men with azoospermia to achieve biological parenthood, because gametes retrieved from testis or epididymis are usable for assisted reproduction. After laboratory processing of surgical specimen the sperm may be used for intracytoplasmic injection and/or cryopreservation. In this article we discuss historical and technical aspects of such procedures and provide critical analysis of their advantages, disadvantages and limitations. Existing laboratory techniques for processing of surgically retrieved sperm are mentioned. We discuss possible future directions for development of testicular biopsy technique aimed at improving sperm retrieval outcomes.

scholarly journals Endocrine Tests and/or Testicular Volume Are Not Predictive of Successful Sperm Retrieval by Multiple Testicular Sperm Extraction in Non-Obstructive Azoospermia

2020 ◽  
Author(s):  
Minh Tam Le ◽  
Thanh Tam Thi Nguyen ◽  
Dac Nguyen Nguyen ◽  
Nhu Quynh Thi Tran ◽  
Quoc Huy Vu Nguyen
Keyword(s):  
Descriptive Analysis ◽  
Testicular Volume ◽  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Sperm Aspiration ◽  
Significant Difference ◽  
Testicular Sperm Aspiration

Abstract Objectives: This study aimed to determine the role of pre-surgical markers in the prediction of sperm retrieval in infertile Vietnamese men with azoospermia. Patients and Methods:Retrospective descriptive analysis of 136 infertile men with azoospermia, examined from August 2014 to July 2018. Patients underwent stepwise surgical sperm retrieval via percutaneous epididymal sperm aspiration, testicular sperm aspiration then multiple testicular sperm extraction in up to 3 locations until sperm were detected. Factorswere analyzed to determine the prediction of sperm retrieval.Results: The overall success rate of sperm retrieval was 49.3% including 88.3% and 18.4% in the OA and NOA group, respectively. The results of sperm retrieval were significantly associated only with the OA and NOA group, not with endocrine test or testicular volume. We found no significant difference in the endocrine test and testicular volume’s result between successful and unsuccessful sperm retrieval in either group.Conclusions: Neither an endocrine test nor testicular volume should be used for predicting the results of surgical sperm retrieval in infertile Vietnamese males with azoospermia.

scholarly journals Testicular Sperm Extraction Techniques in Subfertile Males

2020 ◽  
Vol 3 (1) ◽  
pp. 276-278
Author(s):  
Robin Bahadur Basnet ◽  
Mira Thapa ◽  
Rashmi Shrish ◽  
Preeti Bista
Keyword(s):  
Testicular Sperm Extraction ◽  
Assisted Conception ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Donor Sperm ◽  
Sperm Aspiration ◽  
Sexual Characteristics ◽  
Cheap Method ◽  
Testicular Sperm Aspiration ◽  
Testicular Sperm Retrieval

Introduction: Assisted conception is an option for subfertile couples. Surgical sperm retrieval by testicular sperm aspiration and testicular sperm extraction are widely used safe techniques to yield sperm for intracytoplasmic sperm injection. Experience with these techniques is presented. Materials and Methods: A retrospective study of testicular sperm retrieval for assisted reproduction is presented. Testicular sperm aspiration is attempted on all azoospermic males with normal sexual characteristics. Testicular sperm extraction is attempted on consenting patients where aspiration has failed. Donor sperm injection is done to oocyte of a spouse on the failure of both techniques. Results: Sixty-six percent of males had adequate numbers and characters of viable spermatozoa on testicular sperm aspiration. Further 53.3% of patients where aspiration failed yielded spermatozoa on testicular sperm extraction. Thus overall 77.1 % of patients with azoospermia benefi tted from testicular sperm retrieval techniques. Conclusions: Testicular sperm aspiration is a technically easy, quick, safe, and cheap method of sperm retrieval. Testicular sperm extraction is a safe adjunct to aspiration with better yield.

scholarly journals Predictors of testicular sperm retrieval in patients with non-obstructive azoospermia: a review

2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110027
Author(s):  
Lin Qi ◽  
Ya P Liu ◽  
Nan N Zhang ◽  
Ying C Su
Keyword(s):  
Male Partner ◽  
Serum Testosterone ◽  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Retrieval Rate ◽  
Sperm Aspiration ◽  
Testicular Sperm Aspiration ◽  
Minimal Invasion

Azoospermia is divided into two categories of obstructive azoospermia and non-obstructive azoospermia. Before 1995, couples with a male partner diagnosed with non-obstructive azoospermia had to choose sperm donation or adoption to have a child. Currently, testicular sperm aspiration or micro-dissection testicular sperm extraction combined with intracytoplasmic sperm injection allows patients with non-obstructive azoospermia to have biological offspring. The sperm retrieval rate is significantly higher in micro-dissection testicular sperm extraction compared with testicular sperm aspiration. Additionally, micro-dissection testicular sperm extraction has the advantages of minimal invasion, safety, limited disruption of testicular function, a low risk of postoperative intratesticular bleeding, and low serum testosterone concentrations. Failed micro-dissection testicular sperm extraction has significant emotional and financial implications on the involved couples. Testicular sperm aspiration and micro-dissection testicular sperm extraction have the possibility of failure. Therefore, predicting the sperm retrieval rate before surgery is important. This narrative review summarizes the existing data on testicular sperm aspiration and micro-dissection testicular sperm extraction to identify the possible factor(s) that can predict the presence of sperm to guide clinical practice. The predictors of surgical sperm retrieval in patients with non-obstructive azoospermia have been widely studied, but there is no consensus.

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