scholarly journals Testicular sperm retrieval by percutaneous fine needle sperm aspiration compared with testicular sperm extraction by open biopsy in men with non-obstructive azoospermia

1997 ◽  
Vol 12 (7) ◽  
pp. 1488-1493 ◽  
Author(s):  
S. Friedler ◽  
A. Raziel ◽  
D. Strassburger ◽  
Y. Soffer ◽  
D. Komarovsky ◽  
...  
Keyword(s):  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Open Biopsy ◽  
Sperm Retrieval ◽  
Fine Needle ◽  
Sperm Aspiration ◽  
Testicular Sperm Retrieval

scholarly journals Endocrine Tests and/or Testicular Volume Are Not Predictive of Successful Sperm Retrieval by Multiple Testicular Sperm Extraction in Non-Obstructive Azoospermia

2020 ◽  
Author(s):  
Minh Tam Le ◽  
Thanh Tam Thi Nguyen ◽  
Dac Nguyen Nguyen ◽  
Nhu Quynh Thi Tran ◽  
Quoc Huy Vu Nguyen
Keyword(s):  
Descriptive Analysis ◽  
Testicular Volume ◽  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Sperm Aspiration ◽  
Significant Difference ◽  
Testicular Sperm Aspiration

Abstract Objectives: This study aimed to determine the role of pre-surgical markers in the prediction of sperm retrieval in infertile Vietnamese men with azoospermia. Patients and Methods:Retrospective descriptive analysis of 136 infertile men with azoospermia, examined from August 2014 to July 2018. Patients underwent stepwise surgical sperm retrieval via percutaneous epididymal sperm aspiration, testicular sperm aspiration then multiple testicular sperm extraction in up to 3 locations until sperm were detected. Factorswere analyzed to determine the prediction of sperm retrieval.Results: The overall success rate of sperm retrieval was 49.3% including 88.3% and 18.4% in the OA and NOA group, respectively. The results of sperm retrieval were significantly associated only with the OA and NOA group, not with endocrine test or testicular volume. We found no significant difference in the endocrine test and testicular volume’s result between successful and unsuccessful sperm retrieval in either group.Conclusions: Neither an endocrine test nor testicular volume should be used for predicting the results of surgical sperm retrieval in infertile Vietnamese males with azoospermia.

scholarly journals Efficacy of Testicular Sperm Retrieval by Percutaneous Fine Needle Aspiration in Men with Obstructive Azoospermia

2000 ◽  
Vol 74 (3) ◽  
pp. S76-S77
Author(s):  
A. Tallarini ◽  
A. Borini ◽  
A. Maccolini ◽  
M.A. Bonu ◽  
R. Sciajno ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Fine Needle ◽  
Testicular Sperm Retrieval

Relevance of testicular histopathology on prediction of sperm retrieval rates in case of non-obstructive and obstructive azoospermia

2018 ◽  
Vol 85 (2) ◽  
pp. 60-67 ◽  
Author(s):  
Gianmartin Cito ◽  
Maria E Coccia ◽  
Sara Dabizzi ◽  
Simone Morselli ◽  
Pier A Della Camera ◽  
...  
Keyword(s):  
Follicle Stimulating Hormone ◽  
Needle Aspiration ◽  
Testicular Sperm Extraction ◽  
Total Testosterone ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Maturation Arrest ◽  
Fine Needle ◽  
Normal Spermatogenesis

Introduction: The aim of our research was to establish the relevance of testicular histopathology on sperm retrieval after testicular sperm extraction in patients with non-obstructive azoospermia and in patients with obstructive azoospermia, who already underwent a previous failure testicular fine needle aspiration. Methods: We evaluated a total of 82 azoospermic men, underwent testicular sperm extraction, referring to the Assisted Reproductive Technology Centre of the University of Florence, Italy between January 2008 and March 2017. A general and genital physical examination, scrotal and trans-rectal ultrasound, semen analysis, hormone measurements, including follicle-stimulating hormone, luteinizing hormone and total testosterone, were collected. Results: Successful sperm retrieval was obtained in 36 men of total (43.9%). Successful sperm retrieval was 29.5% in non-obstructive azoospermia patients, while men with obstructive azoospermia, who, underwent a previous failure testicular fine needle aspiration, had sperm retrieval in 86% of cases. Mean luteinizing hormone was 6.55 IU/L, total testosterone 4.70 ng/mL, right testicular volume 13.7 mL and left testicular volume 13.6 mL. Mean Follicle-stimulating hormone was 13.45 IU/L in patients with negative sperm retrieval and 8.18 IU/L in men with successful sperm retrieval. According to histology, 20.7% had normal spermatogenesis, 35.3% hypospermatogenesis, 35.3% maturation arrest and 8.5% Sertoli cell-only syndrome. Successful sperm retrieval was 88.2% in patients with normal spermatogenesis, 24.1% in the maturation arrest group and 48.27% in patients with hypospermatogenesis, while negative sperm retrieval was reported in Sertoli cell-only syndrome patients. Seven cases with maturation arrest showed a successful sperm retrieval. Conclusion: Testicular histopathology after testicular sperm extraction offers important information on prediction of sperm retrieval and can guide the surgeon in choosing the more suitable therapeutic practice.

scholarly journals Outcome of testicular sperm retrieval procedures in non-obstructive azoospermia: percutaneous aspiration versus open biopsy

2000 ◽  
Vol 15 (7) ◽  
pp. 1548-1551 ◽  
Author(s):  
Ramazan Mercan ◽  
Bulent Urman ◽  
Cengiz Alatas ◽  
Senai Aksoy ◽  
Alp Nuhoglu ◽  
...  
Keyword(s):  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Open Biopsy ◽  
Percutaneous Aspiration ◽  
Sperm Retrieval ◽  
Testicular Sperm Retrieval

scholarly journals Successful Targeted Testicular Sperm Extraction Using Microsurgical Technique (microTESE) Following Fine Needle Aspiration (FNA) Mapping in a Non-Obstructive Azoospermia (NOA) Patient: A Case Report

2020 ◽  
Author(s):  
Ponco Birowo ◽  
William Tendi ◽  
Nur Rasyid ◽  
Paul J Turek ◽  
Ivan Rizal Sini ◽  
...  
Keyword(s):  
Male Infertility ◽  
Success Rate ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Current Guideline ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Fine Needle

Background: Management for male infertility can be difficult for some cases. Surgical intervention has long been thought as the last resort to help married couples to conceive. The current guideline recommends testicular sperm extraction with microsurgery technique (microTESE) in severe cases of male infertility. However, the success rate still varies. Thus, a new strategy was needed to further increase the sperm retrieval success rate. Case Presentation: A 39-year-old male with a history of failed sperm extraction, non-obstructive azoospermia (NOA) and Y-chromosomal microdeletion came to the fertility center to undergo sperm retrieval. Fine needle aspiration (FNA) Mapping was performed prior to microTESE to increase the accuracy of sperm retrieval. After further examination with laser assisted immotile sperm selection (LAISS), five spermatozoa were found. Conclusion: The combination of FNA Mapping and microTESE increases the chance of a successful sperm extraction.

scholarly journals Predicting The Ability To Successfully Retrieve Sperm In Infertile Men With Non-obstructive Azoospermia

2019 ◽  
Author(s):  
Minh Tam Le ◽  
Thanh Tam Thi Nguyen ◽  
Quoc Huy Vu Nguyen ◽  
Janelle M. Jackman ◽  
Dinh Duong Le ◽  
...  
Keyword(s):  
Testicular Volume ◽  
University Hospital ◽  
Equation Modeling ◽  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Cross Sectional ◽  
Infertile Men ◽  
Sperm Aspiration

Abstract Objectives: to determine the ability of pre-surgical markers to predict the ability to retrieve sperm in non-obstructive azoospermia (NOA) undergoing surgical sperm retrieval. Methods: a cross-sectional descriptive analysis of 136 infertile patients with azoospermia, examined in the Hue Center for Reproductive Endocrinology and Infertility (HUECREI), Hue University Hospital from August 2014 to July 2018. Patients underwent surgical sperm retrieval in a stepwise manner via percutaneous epididymal sperm aspiration (PESA), testicular sperm aspiration (TESA) then testicular sperm extraction (TESE) until sperm were detected. Patient age, duration of infertility, body mass index (BMI), hormonal profile (FSH, LH & testosterone), and testicular volume were analyzed to determine the predictor of successful sperm retrieval. Analysis was done by univariate & multivariate generalized estimating equation modeling where the primary outcome was sperm retrieved at surgery. Results: In total of 136 infertile men with azoospermia, beside 45 cases with OA, surgical sperm retrieval was successful in 22/91 patients with NOA (24.2%). The group of men with successful sperm retrieval were more likely to live in urban area (P=0.012), higher proportion of normal testicular density (P<0.05), lower serum FSH and serum LH (P<0.001). By multiple logistic regression model, total testicular volume was found to be a only considerable predictor of sperm retrieval in NOA group (OR 1.09, 95%CI 1.013-1.178, P=0.022). Conclusions: The measurement of total testicular volume can be helpful for predicting the successful result of surgical sperm retrieval in Vietnamese infertile men with non-obstructive azoospermia. Key words: testicular ultrasound; endocrine profile; surgical sperm retrieval; non-obstructive; azoospermia.

scholarly journals Testicular Sperm Extraction Techniques in Subfertile Males

2020 ◽  
Vol 3 (1) ◽  
pp. 276-278
Author(s):  
Robin Bahadur Basnet ◽  
Mira Thapa ◽  
Rashmi Shrish ◽  
Preeti Bista
Keyword(s):  
Testicular Sperm Extraction ◽  
Assisted Conception ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Donor Sperm ◽  
Sperm Aspiration ◽  
Sexual Characteristics ◽  
Cheap Method ◽  
Testicular Sperm Aspiration ◽  
Testicular Sperm Retrieval

Introduction: Assisted conception is an option for subfertile couples. Surgical sperm retrieval by testicular sperm aspiration and testicular sperm extraction are widely used safe techniques to yield sperm for intracytoplasmic sperm injection. Experience with these techniques is presented. Materials and Methods: A retrospective study of testicular sperm retrieval for assisted reproduction is presented. Testicular sperm aspiration is attempted on all azoospermic males with normal sexual characteristics. Testicular sperm extraction is attempted on consenting patients where aspiration has failed. Donor sperm injection is done to oocyte of a spouse on the failure of both techniques. Results: Sixty-six percent of males had adequate numbers and characters of viable spermatozoa on testicular sperm aspiration. Further 53.3% of patients where aspiration failed yielded spermatozoa on testicular sperm extraction. Thus overall 77.1 % of patients with azoospermia benefi tted from testicular sperm retrieval techniques. Conclusions: Testicular sperm aspiration is a technically easy, quick, safe, and cheap method of sperm retrieval. Testicular sperm extraction is a safe adjunct to aspiration with better yield.

scholarly journals Predictors of testicular sperm retrieval in patients with non-obstructive azoospermia: a review

2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110027
Author(s):  
Lin Qi ◽  
Ya P Liu ◽  
Nan N Zhang ◽  
Ying C Su
Keyword(s):  
Male Partner ◽  
Serum Testosterone ◽  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Retrieval Rate ◽  
Sperm Aspiration ◽  
Testicular Sperm Aspiration ◽  
Minimal Invasion

Azoospermia is divided into two categories of obstructive azoospermia and non-obstructive azoospermia. Before 1995, couples with a male partner diagnosed with non-obstructive azoospermia had to choose sperm donation or adoption to have a child. Currently, testicular sperm aspiration or micro-dissection testicular sperm extraction combined with intracytoplasmic sperm injection allows patients with non-obstructive azoospermia to have biological offspring. The sperm retrieval rate is significantly higher in micro-dissection testicular sperm extraction compared with testicular sperm aspiration. Additionally, micro-dissection testicular sperm extraction has the advantages of minimal invasion, safety, limited disruption of testicular function, a low risk of postoperative intratesticular bleeding, and low serum testosterone concentrations. Failed micro-dissection testicular sperm extraction has significant emotional and financial implications on the involved couples. Testicular sperm aspiration and micro-dissection testicular sperm extraction have the possibility of failure. Therefore, predicting the sperm retrieval rate before surgery is important. This narrative review summarizes the existing data on testicular sperm aspiration and micro-dissection testicular sperm extraction to identify the possible factor(s) that can predict the presence of sperm to guide clinical practice. The predictors of surgical sperm retrieval in patients with non-obstructive azoospermia have been widely studied, but there is no consensus.

Can Testicular Size Be a Predictive Factor for Successful Sperm Retrieval in Patients with Non Obstructive Azoospermia?

2019 ◽  
pp. 1
Author(s):  
Omer Yumusak ◽  
Mehmet Cinar ◽  
Serkan Kahyaoglu ◽  
Yasemin Tasci ◽  
Gul Nihal Buyuk ◽  
...  
Keyword(s):  
Follicle Stimulating Hormone ◽  
Significant Risk ◽  
High Serum ◽  
Testicular Volume ◽  
Testicular Sperm Extraction ◽  
Total Testosterone ◽  
Obstructive Azoospermia ◽  
Testicular Sperm ◽  
Sperm Retrieval ◽  
Stimulating Hormone

<p><strong>Objective:</strong> Non-obstructive azoospermia, defined as absence of spermatozoa in the ejaculate caused by impaired spermatogenesis, is the most severe cause of male infertility. It is typically presented as high serum follicle stimulating hormone levels and atrophic testis. The combination of intracytoplasmic sperm injection and Microdissection testicular sperm extraction allows these infertile men the opportunity to have their own children from their own testis. Our aim was to evaluate the outcomes of micro-Testicular sperm extraction in men with atrophic testis.</p><p><strong>Study Design:</strong> The medical records of 80 non-obstructive men with azoospermia who underwent micro-TESE were retrospectively evaluated. We assessed clinical parameters; age, duration of infertility, smoking, chromosomal karyotype, Y chromosome microdeletion, follicle stimulating hormone, luteinizing hormone, total testosterone and testicular volume in relation with Microdissection testicular sperm extraction results.</p><p><strong>Results:</strong> Testicular sperm retrieval rate was 53% in 80 patients. Testicular volume, serum follicle stimulating hormone and total testosterone concentrations showed correlation with the results of sperm retrieval. These three parameters were found to be significant risk factors with testicular sperm extraction negative patients (p&lt;0.001). The odds ratios (95% CI) were 6.39 (1.25–26.58), 1.24 (1.11-1.36), 1.13 (0.99-1.21) respectively. Testicular volume was found to be a discriminative parameter in patients with negative sperm retrieval. The cut-off point was established as 6.75 ml for testicular volume with 88.1% sensitivity, 62.1% specificity.</p><p><strong>Conclusion:</strong> Microdissection testicular sperm extraction is the most effective procedure for patients with non-obstructive azoospermia. Testicular volume, serum follicle stimulating hormone and testosterone levels can be predictive factors for sperm retrieval in men with non-obstructive azoospermia.</p>

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