scholarly journals Colposcopic-histologic eligibility criteria for fertility-sparing surgical management in early-stage cervical cancer

2015 ◽  
Vol 86 (6) ◽  
pp. 406-413
Author(s):  
Paweł Basta ◽  
Artur Ludwin ◽  
Łukasz Laskowicz ◽  
Krzysztof Okoń ◽  
Janina Schwartz
2010 ◽  
Vol 17 (6) ◽  
pp. S6
Author(s):  
M.K. Kim ◽  
C.H. Choi ◽  
T. Song ◽  
H.S. Park ◽  
Y-Y. Lee ◽  
...  

2021 ◽  
pp. ijgc-2020-001782
Author(s):  
Blanca Segarra-Vidal ◽  
Jan Persson ◽  
Henrik Falconer

Radical trachelectomy is the ‘cornerstone’ of fertility-sparing surgery in patients with early-stage cervical cancer wishing to preserve fertility. Growing evidence has demonstrated the oncologic safety and subsequent favorable pregnancy outcomes in well-selected cases. In the absence of prospective trials, the decision on the appropriate surgical approach (vaginal, open, or minimally invasive surgery) should be based on local resources and surgeons’ preferences. Radical trachelectomy has the potential to preserve fertility in a large proportion of women with early-stage cervical cancer. However, prematurity and premature rupture of membranes are common obstetric complications after radical trachelectomy for cervical cancer. A multidisciplinary approach is crucial to optimize the balance between oncologic and obstetric outcomes. The purpose of this review is to provide an updated overview of the technical, oncologic, and obstetric aspects of radical trachelectomy.


Author(s):  
Maria Luisa Fais ◽  
Giorgio Candotti ◽  
Giulia Carboni ◽  
Speranza Luisa Anedda ◽  
Valerio Mais ◽  
...  

Recent advances in screening and early diagnosis have decreased cervical cancer incidence and mortality rate in high-resource settings. The postponement of childbearing and the young age of women at diagnosis produced new challenges in the management of this disease. In recent years, attention has been directed to assessing more conservative procedures that can reduce treatment-related morbidity, without compromising oncologic safety and reproductive potential. Fertility sparing surgery (FSS) procedures, including cervical conization, simple or radical trachelectomy with pelvic nodes dissection or sentinel lymph node assessment, and neoadjuvant chemotherapy followed by conization, have shown encouraging results. In this chapter, the authors discuss the role of conservative surgery in the management of early-stage cervical cancer focusing on obstetrical and oncological outcomes.


2019 ◽  
Vol 154 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Giorgio Bogani ◽  
Valentina Chiappa ◽  
Daniele Vinti ◽  
Edgardo Somigliana ◽  
Francesca Filippi ◽  
...  

Author(s):  
Chia-Yi Lee ◽  
Yu-Li Chen ◽  
Ying-Cheng Chiang ◽  
Ching-Yu Cheng ◽  
Yen-Ling Lai ◽  
...  

We aimed to investigate the outcomes and subsequent pregnancies of early-stage cervical cancer patients who received conservative fertility-sparing surgery. Women with early-stage cervical cancer who underwent conservative or fertility-sparing surgery in a tertiary medical center were reviewed from 2004 to 2017. Each patient’s clinicopathologic characteristics, adjuvant therapy, subsequent pregnancy, and outcome were recorded. There were 32 women recruited, including 12 stage IA1 patients and 20 stage IB1 patients. Twenty-two patients received conization/LEEP and the other 10 patients received radical trachelectomy. Two patients did not complete the definite treatment after fertility-sparing surgery. There were 11 women who had subsequent pregnancies and nine had at least one live birth. The live birth rate was 73.3% (11/15). We conclude that patients with early-stage cervical cancer who undergo fertility-sparing surgery can have a successful pregnancy and delivery. However, patients must receive a detailed consultation before surgery and undergo definitive treatment, if indicated, and regular postoperative surveillance.


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