Blood flow in the umbilical vein of the fetus in first half of pregnancy

2021 ◽  
Vol 50 (2) ◽  
pp. 85-89
Author(s):  
E. K. Ailamazyan ◽  
A. A. Polyanin ◽  
A. V. Michailov ◽  
I. Ju. Kogan ◽  
N. N. Konstantinova ◽  
...  
Keyword(s):  
Blood Flow ◽  
Umbilical Vein ◽  
Normal Pregnancy ◽  
Flow Speed

The present investigation aims at studying the blood flow in the umbilical vein in the first half of normal pregnancy. It was shown that the establishing of hemocirculation passes through 4 periods: 8- 10th, 11-12th, 13-16th and after the 16th week of pregnancy. Besides that, statistically verified changes in maximum blood flow speed and index of pulsation in this vessel were revealed. Constant bloodstream spectrum reflects stability of oxygenic bloodsupply of the fetus.

Antenatal fetal blood flow in the descending aorta and in the umbilical vein and their ratio in normal pregnancy

1988 ◽  
Vol 14 (4) ◽  
pp. 263-268 ◽  
Author(s):  
H.Y. Chen ◽  
F.M. Chang ◽  
H.C. Huang ◽  
F.J. Hsieh ◽  
C.C. Lu
Keyword(s):  
Blood Flow ◽  
Umbilical Vein ◽  
Normal Pregnancy ◽  
Fetal Blood ◽  
Descending Aorta

scholarly journals Inhibitory Effects of seco-Triterpenoids from Acanthopanax sessiliflorus Fruits on HUVEC Invasion and ACE Activity

2015 ◽  
Vol 10 (9) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Jin-Won Lee ◽  
Nam-In Baek ◽  
Dae-Young Lee
Keyword(s):  
Blood Flow ◽  
Crude Extract ◽  
Umbilical Vein ◽  
Inhibitory Effect ◽  
Inhibitory Effects ◽  
Ace Inhibitory Activity ◽  
Dioic Acid ◽  
Acanthopanax Sessiliflorus ◽  
Ace Activity ◽  
Very High

This study was conducted to investigate the effects of the crude extract from Acanthopanax sessiliflorus fruits and the isolated seco-triterpenoids from the crude extract on blood flow in human umbilical vein endothelial cell (HUVEC) invasion assay and angiotensin converting enzyme (ACE) inhibitory activity assay. On the basis of DMSO, the extent of HUVECs'invasion was remarkably decreased with crude extract concentrations of 400 and 1000 μg/mL. Additionally, the extent of the HUVEC invasion inhibitory effect in 400 and 1000 μg/mL of acanthosessilioside F were 55.8% and 72.4%, respectively. In addition, the maximum extent of the HUVEC invasion inhibitory effect of 22-α-hydroxychiisanoside was 88.9%. The IC50 value of the inhibitory effect on ACE activity in the crude extract was 4 μg/mL. The isolated seco-triterpenoids, 22α-hydroxychiisanogenin, 3,4- seco-lupan-20(30)-en-3,28-dioic acid, (1 R)-1,4-epoxy-11α,22α-hydroxy-3,4- seco-lupan-20(30)-en-3,28-dioicacid, (+)-divaroside, and chiisanosidehad showed very high inhibitory effects on ACE activity, ranging from 1.8 to 2.9 üg/mL, which is much higher than the 150.0 üg/mL effect of aspirin. These results suggest that the crude extract from Acanthopanax sessiliflorus fruits and the isolated seco-triterpenoids from the crude extract enhance the blood flow effect by decreasing ACE activity.

scholarly journals Maternal Uterine Vascular Remodeling During Pregnancy

Physiology ◽  
2009 ◽  
Vol 24 (1) ◽  
pp. 58-71 ◽  
Author(s):  
George Osol ◽  
Maurizio Mandala
Keyword(s):  
Extracellular Matrix ◽  
Blood Flow ◽  
Vascular Remodeling ◽  
Normal Pregnancy ◽  
Uterine Blood Flow ◽  
Growth And Remodeling ◽  
Cellular Mechanisms ◽  
Cellular Processes ◽  
Uteroplacental Blood Flow ◽  
Uterine Circulation

Sufficient uteroplacental blood flow is essential for normal pregnancy outcome and is accomplished by the coordinated growth and remodeling of the entire uterine circulation, as well as the creation of a new fetal vascular organ: the placenta. The process of remodeling involves a number of cellular processes, including hyperplasia and hypertrophy, rearrangement of existing elements, and changes in extracellular matrix. In this review, we provide information on uterine blood flow increases during pregnancy, the influence of placentation type on the distribution of uterine vascular resistance, consideration of the patterns, nature, and extent of maternal uterine vascular remodeling during pregnancy, and what is known about the underlying cellular mechanisms.

Role of ductus venosus in distribution of umbilical blood flow in human fetuses during second half of pregnancy

2000 ◽  
Vol 279 (3) ◽  
pp. H1256-H1263 ◽  
Author(s):  
Maria Bellotti ◽  
Giancarlo Pennati ◽  
Camilla De Gasperi ◽  
Frederick C. Battaglia ◽  
Enrico Ferrazzi
Keyword(s):  
Blood Flow ◽  
Fetal Liver ◽  
Color Doppler ◽  
Liver Perfusion ◽  
Normal Pregnancy ◽  
Left Lobe ◽  
Ductus Venosus ◽  
Venous Circulation ◽  
Umbilical Blood ◽  
Umbilical Blood Flow

Color Doppler sonography was used to study umbilical and ductus venosus (DV) flow in 137 normal fetuses between 20 and 38 wk of gestation. Hepatic flows were also evaluated. In all parts of the venous circulation examined, blood flow increased significantly with advancing gestational age. The weight-specific amniotic umbilical flow did not change significantly during gestation (120 ± 44 ml · min−1 · kg−1), whereas DV flow decreased significantly (from 60 to 17 ml · min−1 · kg−1). The percentage of umbilical blood flow shunted through the DV decreased significantly (from 40% to 15%); consequently, the percentage of flow to the liver increased. The right lobe flow changed from 20 to 45%, whereas the left lobe flow was approximately constant (40%). These changes are related to different patterns of growth of the umbilical veins and DV diameters. The present data support the hypothesis that the DV plays a less important role in shunting well-oxygenated blood to the brain and myocardium in late normal pregnancy than in early gestation, which leads to increased fetal liver perfusion.

scholarly journals Modern representation about venous circulation in fetoplacental system

1999 ◽  
Vol 48 (3) ◽  
pp. 10-14
Author(s):  
E. K. Ailamazyan ◽  
N. N. Konstantinova ◽  
A. A. Polyanin ◽  
I. U. Kogan
Keyword(s):  
Blood Flow ◽  
Gestational Age ◽  
Venous Return ◽  
Umbilical Vein ◽  
Functional Importance ◽  
Venous Circulation ◽  
The Given ◽  
Venous Vessel

The development of venous circulation in fetoplacental system is one of the least known problems in perinatology. In work by a method of ultrasonic Doppler is investigated the development of blood flow in umbilical vein, v. cava inferior and jugulaar veins of a fetus with 8-th on 40-th week of normally developing pregnancy. It is shown, that the parameters of blood flow in the given vessels depends on gestational age of a fetus, conditions of venous return to heart and functional importance of venous vessel.

Fetal oxygen uptake, oxygenation, and acid-base balance as a function of uterine blood flow

1983 ◽  
Vol 244 (6) ◽  
pp. H749-H755 ◽  
Author(s):  
R. B. Wilkening ◽  
G. Meschia
Keyword(s):  
Blood Flow ◽  
Base Excess ◽  
Umbilical Vein ◽  
Delivery Rate ◽  
Uterine Blood Flow ◽  
O2 Uptake ◽  
Acid Base Balance ◽  
Venous Pco2 ◽  
Base Balance ◽  
O2 Delivery

The rate of O2 delivery to the pregnant uterus (FaO2) was decreased in chronic sheep preparations by mechanical occlusion of uterine blood flow. The relationship of uterine venous O2 saturation (SVO2) to FaO2 was curvilinear with convexity toward the SVO2 axis. As SVO2 decreased, there was a decrease in uterine and umbilical venous O2 tension (PO2), with no appreciable reduction of the PO2 difference between the two veins and a decrease in the umbilical vein O2 delivery rate. Fetal O2 uptake and base excess remained normal as the umbilical vein O2 delivery rate was reduced from 1.1 to 0.6 mmol . min-1 . kg-1 but decreased markedly at an O2 delivery rate less than 0.5. Umbilical venous CO2 tension (PCO2) was higher than, and strongly correlated with, uterine venous PCO2 (R = 0.954). These observations support a venous equilibration model of ovine placental exchange and demonstrate that under normal physiological conditions the O2 supply to the fetal lamb is approximately twice the value necessary to maintain an adequate fetal O2 uptake and a normal fetal base excess.

scholarly journals Prenatal diagnosis of varix of the fetal intraabdominal umbilical vein: Case report

2008 ◽  
Vol 61 (1-2) ◽  
pp. 75-78 ◽  
Author(s):  
Aleksandra Novakov-Mikic ◽  
Sinisa Stojic
Keyword(s):  
Blood Flow ◽  
Case Report ◽  
Prenatal Diagnosis ◽  
Anterior Abdominal Wall ◽  
Umbilical Vein ◽  
Color Doppler ◽  
Contemporary Literature ◽  
Ultrasound Scan ◽  
Lower Edge ◽  
Doppler Examination

Varix of intraabdominal part of fetal umbilical vein is during a prenatal ultrasound scan seen as a hypoechogenic mass between anterior abdominal wall and lower edge of liver, and the diagnosis is confirmed when blood flow is seen during color Doppler examination. A case of prenatal diagnosis of this abnormality is presented, with review of contemporary literature regarding diagnosis and management as well as the outcome of such pregnancies.

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