Study of different genotypes of Vitamin-D Receptor (VDR) Gene Polymorphisms in Patients Eligible for Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) from a Sibling Donor

SECI Oncology ◽  
2016 ◽  
Vol 2016 ◽  
Author(s):  
Ashraf Zedan
Keyword(s):  
Vitamin D ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Vitamin D Receptor ◽  
Gene Polymorphisms ◽  
Vdr Gene ◽  
Hematopoietic Stem ◽  
Vdr Gene Polymorphisms

Cytomegalovirus Infection Downregulates Vitamin-D Receptor in Patients Undergoing Hematopoietic Stem Cell Transplantation

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Oliver Robak ◽  
Marie-Theres Kastner ◽  
Carmen Stecher ◽  
Martina Schneider ◽  
Martin Andreas ◽  
...  
Keyword(s):  
Vitamin D ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Vitamin D Receptor ◽  
Cytomegalovirus Infection ◽  
Hematopoietic Stem

scholarly journals Vitamin D Deficiency and Oral Mucositis in Hematopoietic Stem Cell Transplantation: A Cross-Sectional Observation

2019 ◽  
Author(s):  
Kosar Raoufinejad ◽  
Shahrzad Pezeshki ◽  
Bahram Chahardouli ◽  
Molouk Hadjibabaie ◽  
Zahra Jahangard-Rafsanjani ◽  
...  
Keyword(s):  
Vitamin D ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Hospital Stay ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Oral Mucositis ◽  
World Health ◽  
Hematopoietic Stem

Backgrounds: One of the most frequent complications of high-dose chemotherapy regimen before hematopoietic stem cell transplantation (HSCT) is oral mucositis (OM). Vitamin D (VD) has well-known immunoregulatory, anti-inflammatory, and antioxidant properties.This study aimed to evaluate the association of pre-HSCT VD levels with OM as well as neutrophil and platelet engraftments in patients with multiple myeloma, Hodgkin’s and non-Hodgkin’s lymphoma after autologous HSCT. Methods: A sample of 71 patients was enrolled after obtaining informed consent. Serum samples were collected in the morning prior to the administration of conditioning regimen to measure the 25-OH-D. OM was examined daily during hospital stay. The World Health Organization (WHO) scale was used for scoring the OM. Absolute neutrophil count and platelet count were determined daily from transplantation until engraftment. Results: Patients aged 18-65 years. Mean length of hospital stay was 15.8±5.7 days. OM was detected in 44/71 (62.0%) of patients. Mean time to the engraftment of neutrophils and platelets were 11.8±4.0 and 17.2±7.3 days, respectively. Mean level of 25-OH-D was 17.5±14.0 ng/ml. VD deficiency (<20 ng/ml) was diagnosed in 51/71 (71.8%) of patients. No association between the 25-OH-D levels and incidence of OM (P=0.69) or OM grade 3-4 (P=0.46) was found. No significant correlations were detected between the 25-OH-D and engraftment time of neutrophils (P=0.46) or platelets (P=0.17). Conclusions: The prevalence of VD deficiency was high among adult HSCT patients at the time of transplantation. No association was found between the pre-HSCT VD level and OM or engraftment time.

scholarly journals Single Ultra-High-Dose Cholecalciferol to Prevent Vitamin D Deficiency in Pediatric Hematopoietic Stem Cell Transplantation

2018 ◽  
Vol 24 (9) ◽  
pp. 1856-1860 ◽  
Author(s):  
Gregory Wallace ◽  
Sonata Jodele ◽  
Kasiani C. Myers ◽  
Christopher E. Dandoy ◽  
Javier El-Bietar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Vitamin D Deficiency ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
High Dose ◽  
Hematopoietic Stem

The impact of cytokine gene polymorphisms on the outcome of HLA matched sibling hematopoietic stem cell transplantation

Cytokine ◽  
2018 ◽  
Vol 110 ◽  
pp. 404-411 ◽  
Author(s):  
Azza M. Kamel ◽  
Abdallah Gameel ◽  
Gamal T.A. Ebid ◽  
Eman R. Radwan ◽  
Mostafa F. Mohammed Saleh ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Gene Polymorphisms ◽  
Cytokine Gene ◽  
Hematopoietic Stem ◽  
Matched Sibling ◽  
Cytokine Gene Polymorphisms ◽  
The Impact

scholarly journals Effects of Vitamin D Levels on Outcomes after Allogeneic Hematopoietic Stem Cell Transplantation in Children

2019 ◽  
Vol 25 (3) ◽  
pp. S239-S240
Author(s):  
Rajinder PS Bajwa ◽  
Kimberly Taylor ◽  
Amanda R. Hoyt ◽  
Manmohan Kamboj ◽  
Jeffery J. Auletta ◽  
...  
Keyword(s):  
Vitamin D ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Hematopoietic Stem ◽  
Vitamin D Levels
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