Peripheral Venous Malformations With a Dominant Outflow Vein: Results of Ethanol Embolization

Abstract. Background: Congenital venous malformations are frequently treated with sclerotherapy. Primary treatment goal is to control the often size-related symptoms. Functional impairment and aesthetical aspects as well as satisfaction have rarely been evaluated. Patients and methods: Medical records of patients who underwent sclerotherapy of spongiform venous malformations were reviewed and included in this retrospective study. The outcome of sclerotherapy as self-reported by patients was assessed in a 21 item questionnaire. Results: Questionnaires were sent to 166 patients with a total of 327 procedures. Seventy-seven patients (48 %) with a total of 159 procedures (50 %) responded to the survey. Fifty-seven percent of patients were male. The age ranged from 1 to 38.1 years with a median age of 16.4 years. The lower extremities were the most common treated area. Limitations caused by the venous malformation improved in the majority of patients (e.g. pain improvement 87 %, improvement of swelling 83 %) but also worsening of symptoms occurred in a minority of cases. Seventy-seven per cent would undergo sclerotherapy again. Conclusions: Sclerotherapy for treatment of venous malformations results in significant reduction of symptoms. Multiple treatments are often needed, but patients are willing to undergo them.

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Faculty Opinions recommendation of Stereotactic fractionated radiotherapy for cavernous venous malformations (hemangioma) of the orbit.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717948804.793453905 ◽

2012 ◽

Author(s):

Michael Kazim ◽

Payal Patel

Keyword(s):

Venous Malformations ◽

Fractionated Radiotherapy ◽

Stereotactic Fractionated Radiotherapy

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Novel Compliant Stent with Specific Design for Truncular Venous Malformations: Results of a Porcine Model Study

European Journal of Vascular and Endovascular Surgery ◽

10.1016/j.ejvs.2019.06.1200 ◽

2019 ◽

Vol 58 (6) ◽

pp. e514-e515

Author(s):

Pierfrancesco Veroux ◽

Alessia Giaquinta ◽

Giulia Bernardini ◽

Carla Virgilio ◽

Massimiliano Veroux

Keyword(s):

Porcine Model ◽

Venous Malformations ◽

Specific Design ◽

Model Study

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Endonasal resection of orbital cavernous venous malformations with septal preservation

American Journal of Otolaryngology ◽

10.1016/j.amjoto.2021.103021 ◽

2021 ◽

pp. 103021

Author(s):

Wilson P. Lao ◽

Hector A. Perez ◽

Kristelle J. Lagabon ◽

Kenneth De Los Reyes ◽

Steve C. Lee

Keyword(s):

Venous Malformations

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Hybrid treatment of fibroadipose vascular anomaly: A case report

Open Medicine ◽

10.1515/med-2020-0228 ◽

2020 ◽

Vol 15 (1) ◽

pp. 890-897

Author(s):

Francesco Stillo ◽

Federica Ruggiero ◽

Antonio De Fiores ◽

Rita Compagna ◽

Bruno Amato

Keyword(s):

Patient Satisfaction ◽

Vascular Anomaly ◽

Rare Type ◽

Complete Excision ◽

Hybrid Treatment ◽

Constant Pain ◽

Additional Surgery ◽

Ethanol Embolization

AbstractBackgroundFirst identified in 2014, fibroadipose vascular anomaly (FAVA) is a very rare type of venous and lymphatic malformation. Marked by tough fibrofatty tissue in the extremities overtaking portions of the muscles, it is associated with constant pain and contracture of the affected extremity. There is a paucity of literature, and no guidelines on treatment procedure are available. This case highlights the role of hybrid treatment with primary ethanol percutaneous ethanol embolization and additional surgery for radicality in excision of FAVA lesions.Case summaryA 9-year-old girl with FAVA underwent the hybrid treatment. The achievements of complete excision, clinical response, and patient satisfaction in long-term follow-up were assessed. Following the hybrid treatment, the patient experienced significant improvement in pain. Concurrent symptoms of physical limitation, leg swelling, and skin hyperesthesia also improved. The clinical benefit, supported by postoperative physiotherapy, was well stabilized at 6-month follow-up, resulting in complete patient satisfaction at 12- and 36-month follow-ups. No major complications were encountered.ConclusionEthanol embolization plus surgery is a safe, effective, and long-term hybrid treatment of symptomatic FAVA lesions.

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Endovascualr Embolization of Brain Arterio-Venous Malformations Using Extended Onyx Injection Technique

10.1055/s-0041-1729823 ◽

2017 ◽

Author(s):

Waseem Aziz

Keyword(s):

Injection Technique ◽

Venous Malformations

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Subconjunctival Hemorrhage in a Child with the Blue Rubber Bleb Nevus Syndrome on Treatment with Oral Propranolol

Case Reports in Ophthalmology ◽

10.1159/000513504 ◽

2021 ◽

pp. 451-456

Author(s):

Karen De Loecker ◽

Veerle Labarque ◽

Hilde Seynaeve ◽

Ingele Casteels

Keyword(s):

Central Nervous System ◽

Topical Treatment ◽

Vascular Lesions ◽

Venous Malformations ◽

Timolol Maleate ◽

Cutaneous Lesions ◽

Subconjunctival Hemorrhage ◽

First Case ◽

Β Blocker ◽

Oral Propranolol

Blue rubber bleb nevus syndrome (BRBNS) is a rare syndrome characterized by venous malformations of mostly skin and gastrointestinal tract. Patients present with multiple venous malformations in various organs including liver, spleen, heart, eye, and central nervous system. Few ophthalmological cases have been published in literature and at present, there are no clear guidelines on the treatment of eye hemorrhages associated with the BRBNS. We report a 3-year-old boy with the BRBNS who developed a spontaneous progressive enlarging subconjunctival hemorrhage in the left eye despite being treated with oral propranolol. The subconjunctival hemorrhage was caused by an underlying conjunctival vascular malformation. With topical treatment with timolol maleate 0.5% once a day in the affected eye, the lesion regressed completely after 4 months. This child represents the first case of the BRBNS associated with a subconjunctival progressive bleeding necessitating topical treatment despite oral propranolol effectively controlling the cutaneous lesions. We recommend ophthalmic screening of patients with BRBNS in early childhood. For patients with BRBNS-related subconjunctival vascular lesions with subsequent hemorrhage, treatment with a topical β-blocker may be an efficient and harmless treatment option.

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