Duodenal Metastasis From a Rectal Malignant Melanoma Primary: A Case Report

Duodenal melanoma constitutes a very small number of gastrointestinal malignant melanomas. The small intestine is a common site for the metastatic spread of cutaneous melanomas; however, its metastatic involvement from a primary rectal melanoma origin has seldom been reported. We present the histopathologic features of an unusual case of primary rectal melanoma metastasizing to the duodenum.

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Primary rectal melanoma - a case report

Medical Journal of Indonesia ◽

10.13181/mji.v23i4.1006 ◽

2015 ◽

Vol 23 (4) ◽

pp. 229-31 ◽

Cited By ~ 1

Author(s):

Somak Das ◽

Tuhin S. Mandal ◽

Souvik Paul ◽

Purnendu Datta ◽

Aloke K. Sinhababu

Keyword(s):

Case Report ◽

Malignant Melanoma ◽

Rectal Bleeding ◽

Polypoid Lesion ◽

Bowel Habit ◽

Radical Excision ◽

Common Site ◽

Altered Bowel Habit ◽

Rectal Melanoma ◽

Anorectal Region

The most common site for malignant melanoma is skin, then eye and third is anorectal region. Primary anorectal malignant melanoma is still very uncommon. It is usually very aggressive and presents with altered bowel habit and rectal bleeding. Proctoscopy shows non-pigmented or lightly pigmented polypoid lesion. Histopathology is confirmatory. Early radical excision is mandatory. A 56 year-old female was presented with malignant melanoma of the lower third of rectum. We report this case for its rarity.

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Malignant melanoma of the rectum presenting as cloacogenic polyp: a case report

Annals of The Royal College of Surgeons of England ◽

10.1308/rcsann.2019.0160 ◽

2020 ◽

Vol 102 (3) ◽

pp. e67-e69

Author(s):

JD Coyne ◽

P O’Byrne

Keyword(s):

Case Report ◽

Malignant Melanoma ◽

Mucosal Prolapse ◽

Mucosal Melanoma ◽

Common Condition ◽

Malignant Melanomas ◽

Anorectal Region

Mucosal malignant melanomas are uncommon. It is rare for a primary mucosal melanoma to occur in the anorectal region. Anorectal polypoid mucosal prolapse however, is a relatively common condition. We report a case of malignant melanoma presenting as mucosal prolapse and inducing changes similar to inflammatory cloacogenic polyp.

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Malignant melanoma of the bladder: A case report

Canadian Urological Association Journal ◽

10.5489/cuaj.1242 ◽

2014 ◽

Vol 8 (1-2) ◽

pp. 54 ◽

Cited By ~ 6

Author(s):

Hamide Sayar ◽

Seyda Erdogan ◽

Fulya Adamhasan ◽

Esma Gurbuz ◽

Mehmet Fatih İnci

Keyword(s):

Case Report ◽

Malignant Melanoma ◽

Immunohistochemical Staining ◽

Correct Diagnosis ◽

Primary Lesion ◽

Histological Features ◽

Malignant Melanomas ◽

Metastatic Lesions ◽

S 100 ◽

Hmb 45

Primary malignant melanoma of the bladder is very rare. Rather than being a primary lesion, malignant melanomas of the bladder are more commonly metastatic lesions. The histopathological appearance largely does not differ from that of melanoma at other body sites. It is often difficult to discriminate whether a bladder melanoma is primary or metastatic. Therefore, a careful review of histological features and performing necessary immunohistochemical staining procedures for S-100 protein and HMB-45 are very important in achieving a correct diagnosis. We report a case of hypomelanotic malignant melanoma of the bladder. Despite the variety of therapies available for primary melanomas of the bladder, the prognosis is still poor.

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An Unusual Case Report of Malignant Melanoma of the Sphenoid Sinus with Review of Literature

Indian Journal of Otolaryngology and Head & Neck Surgery ◽

10.1007/s12070-019-01787-8 ◽

2020 ◽

Author(s):

Ghanashyam Mandal ◽

Vishal Yadav ◽

Vikas Arora ◽

Ajay Kumar Dewan

Keyword(s):

Case Report ◽

Malignant Melanoma ◽

Sphenoid Sinus ◽

Unusual Case ◽

Review Of Literature ◽

Unusual Case Report

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Pigmented tumors in fallow deer (Dama dama): 11 cases

Journal of Veterinary Diagnostic Investigation ◽

10.1177/1040638717707789 ◽

2017 ◽

Vol 29 (4) ◽

pp. 483-488 ◽

Cited By ~ 2

Author(s):

Kelly L. Hughes ◽

Rob J. Bildfell ◽

Benjamin Alcantar

Keyword(s):

Malignant Melanoma ◽

Final Diagnosis ◽

Pulmonary Involvement ◽

Fallow Deer ◽

Primary Lesion ◽

Positive Staining ◽

Dama Dama ◽

Clinical Progression ◽

Malignant Melanomas ◽

Histopathologic Features

Pigmented tumors have been reported infrequently in captive deer. We document herein the clinical progression and gross and histopathologic features of pigmented tumors diagnosed as melanoma and pigmented schwannoma in 11 white fallow deer ( Dama dama). Affected animals were part of a captive herd maintained at a drive-through park in southern Oregon and were 5–17 y of age during the study period (2004–2013). Primary lesion locations included periocular, perineal, and neck tissues, with cutaneous and internal metastases later identified at autopsy in some cases of malignant melanoma. Diagnoses included 7 malignant melanomas, 2 benign melanomas, and 2 pigmented schwannomas. Diagnosis of melanoma was based on typical histomorphologic features, and final diagnosis of pigmented schwannomas was based on histomorphologic features with negative staining for melan A and positive staining for laminin. Metastasis was found in 3 of 7 cases diagnosed as malignant melanoma; 2 had extensive pulmonary involvement and resulted in euthanasia of the animal; 1 animal developed eyelid and ear lesions that also resulted in euthanasia.

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Recurrence of uveal malignant melanoma: a case report

Nepalese Journal of Ophthalmology ◽

10.3126/nepjoph.v5i2.8744 ◽

2013 ◽

Vol 5 (2) ◽

pp. 275-278

Author(s):

Madhu Thapa ◽

GB Shrestha ◽

AK Sharma ◽

S Karki ◽

S Khanal

Keyword(s):

Case Report ◽

Adjuvant Chemotherapy ◽

Malignant Melanoma ◽

Early Diagnosis ◽

Uveal Melanoma ◽

Unusual Case ◽

Uveal Tract ◽

Uveal Malignant Melanoma ◽

Ocular Morbidity

Background: Malignant melanoma of uveal tract is a rare ocular malignancy. It is one of the significant causes of ocular morbidity and mortality which is less commonly seen in children. Case: We report an unusual case of orbital recurrence of malignant melanoma in a 14-yearold boy who had previously undergone enucleation of the left painful blind eye 8 months ago. He was diagnosed to have uveal malignant melanoma elsewhere which was confirmed by histopathology. Orbital recurrence was managed with modified exenteration with adjuvant chemotherapy and radiotherapy. Conclusion: In all treated cases of uveal melanoma, close follow up examination and monitoring is necessary for early diagnosis of the recurrence and to plan for further management. Nepal J Ophthalmol 2013; 5(10): 275-278 DOI: http://dx.doi.org/10.3126/nepjoph.v5i2.8744

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Primary malignant melanoma of the duodenum: a rare case report

International Surgery Journal ◽

10.18203/2349-2902.isj20184663 ◽

2018 ◽

Vol 5 (11) ◽

pp. 3771

Author(s):

Villalan Ramasamy ◽

Anand Lakshmanan ◽

Senthilkumaran Govindaraj Raman ◽

Kannan Devigounder

Keyword(s):

Small Intestine ◽

Case Report ◽

Malignant Melanoma ◽

Rare Case ◽

Primary Melanoma ◽

Skin Melanoma ◽

Gi Tract ◽

Rare Case Report ◽

Anorectal Region ◽

Localized Disease

Malignant melanoma especially primary melanoma is uncommon in the gastrointestinal (GI) tract. GI melanomas are usually metastatic from skin melanoma. Anorectal region and small bowel are the most common sites of primary and metastatic GI melanoma respectively. Various theories have been put forward to explain the origin of Primary Melanoma of Small intestine. Melanomas of the GI tract can produce range of symptoms based on their location and size. Surgery is the main stay of treatment for localized disease. We reported a case of primary duodenal melanoma which was managed by surgically.

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