The Effect of Platelet Rich Plasma on Tissue Healing after Mandibular Third Molar Surgery

2021 ◽  
Author(s):  
Negin Karimi ◽  
Behnam Khorrami ◽  
Reza Nezhadnasrollah ◽  
Yamin Haghani
Keyword(s):  
Soft Tissue ◽  
Third Molar ◽  
Test Group ◽  
Third Molar Surgery ◽  
P Value ◽  
Soft Tissue Healing ◽  
Tissue Healing ◽  
Mandibular Third Molar ◽  
The Mean ◽  
Mandibular Third Molar Surgery

Introduction: This study aimed, effect of platelet-rich plasma (PRP) on soft tissue healing after mandibular third molar surgery. Materials & Methods: In this semi-blinded clinical trial study,30 selected patients requiring surgical extraction of soft tissue impacted mandibular third molar participated from cases referred to the Department of Surgery, Faculty of Dentistry, Isfahan Azad University 2017.Patients divided into both test and control groups. PRP was placed in the extracted socket of the test group, whereas the control group had no PRP. Arzhangian standard kit utilized for preparation of PRP. The outcome variables in this study were pain, swelling, inter incisal mouth opening, wound dehiscence, dry socket, bleeding, and tissue color. The collected data analyzed using statistical tests followed independent T-test, Mann-Whitney, and fisher (p value < 0.05). Results: The mean postoperative pain score (Visual Analog Scale) lowered for the test group after several wound dehiscence on the third and seventh days after surgery which was statistically significant (p value < 0.001). Although the mean bleeding time on the third day after surgery decreased in the test group, this difference was not statistically significant (p value = 0.59). There were no statistically significant between both groups for The dry socket incidence on the seventh day and the mean of inter incisal mouth opening in the third and seventh days after surgery as well. Conclusion: The usage of topical PRP has beneficial advantages on soft tissue healing after mandibular third molar surgery. Unlike the control group, The PRP group provided reduced pain and better soft tissue healing.

scholarly journals The Effect of Oral Ketorolac Compared to Ibuprofen on Edema, Trismus, and Pain After Mandibular Third Molar Surgery

2021 ◽  
Vol 13 (4) ◽  
pp. 130-134
Author(s):  
Mostafa Govahi ◽  
Hamidreza Ajami ◽  
Vahid Khalili ◽  
Ayda Paydar ◽  
Gooya Kabir
Keyword(s):  
Statistical Tests ◽  
Third Molar ◽  
Mouth Opening ◽  
Third Molar Surgery ◽  
P Value ◽  
Third Molar Extraction ◽  
Mandibular Third Molar ◽  
Mandibular Third Molar Surgery ◽  
The One ◽  
Surgery Department

Background: Latent third molar extraction is the most common surgery in dentistry. Common complications of this surgery include pain, swelling, and trismus. To control these side effects, several drugs have been developed and evaluated in various studies. However, the present study is the first one to compare the effects of ibuprofen and ketorolac on pain, swelling, and trismus after molar surgery. Methods: This study was a split-mouth clinical trial. To conduct the trial, 20 candidates were selected from among patients referring to Surgery Department of the Dentistry School at Yazd Shahid Sadoughi University of Medical Sciences for mandibular third molar removal surgery. The patients were divided into two groups after the surgery: one group received ibuprofen, and the other one received ketorolac. Pain, swelling, and trismus were evaluated prior to the surgical procedure, 24 hours later, and one week after the surgery. Data were analyzed by SPSS software version 22 by using Wilcoxon statistical tests and paired t test. Results: Ibuprofen and ketorolac had similar effects on pain relief (P value>0.05). Studying the two groups produced similar results regarding improvement in mouth opening (P value>0.05). Improvement pace of the postoperative swelling was significantly faster in the group receiving ketorolac compared to the one receiving ibuprofen (P value <0.05). Conclusions: It was concluded that ibuprofen and ketorolac had positive and almost similar effects on pain control, edema, and trismus after molar surgery. However, ketorolac was more effective in controlling edema after surgery.

scholarly journals Analgesic Efficacy of Tramadol and Butorphanol in Mandibular Third Molar Surgery: A Comparative Study

2012 ◽  
Vol 13 (3) ◽  
pp. 364-370 ◽  
Author(s):  
Syed Sirajul Hassan ◽  
Anees Ahmed ◽  
Manjunath Rai ◽  
TM Kalappa
Keyword(s):  
Postoperative Pain ◽  
Comparative Study ◽  
Third Molar ◽  
Analgesic Efficacy ◽  
Third Molar Surgery ◽  
Tramadol Hydrochloride ◽  
Mandibular Third Molar ◽  
Duration Of Surgery ◽  
The Mean ◽  
Mandibular Third Molar Surgery

ABSTRACT Background Butorphanol tartrate, a mixed synthetic agonistantagonist opioid analgesic has been used for management of postoperative pain in minor and major surgical procedures.14,20 Tramadol hydrochloride is a centrally acting opioid which is effectively used in postoperative pain in various minor and major surgeries. Materials and methods Twenty subjects selected randomly received butorphanol tartrate 1 mg intramuscular and 20 subjects received tramadol hydrochloride 50 mg intramuscular after the removal of mandibular third molars. Time of injection, amount of anesthetic injected, duration of surgery, adverse effects were recorded.21 Results The mean amount of LA administered in butorphanol group was 2.6450 ml and in tramadol group was 2.640 ml respectively, the mean duration for surgery was 56.75 and 53.5 minutes for butorphanol and tramadol groups respectively which was statistically not significant. Pain assessment was done with VAS which showed mean of 19.2 and 15.5 mm (p = 0.001) which was significant for butorphanol and tramadol respectively after 12 hours. The mean time for rescue medication requirement was 5.9 hours (for tramadol) and 8.4 hours (for butorphanol). Effective analgesic activity was seen by butorphanol 1 mg intramuscular then tramadol 50 mg. Conclusion Butorphanol 1 mg was more effective than tramadol 50 mg in respect to postoperative analgesia. How to cite this article Hassan SS, Ahmed A, Rai M, Kalappa TM. Analgesic Efficacy of Tramadol and Butorphanol in Mandibular Third Molar Surgery: A Comparative Study. J Contemp Dent Pract 2012;13(3):364-370.

Prophylactic antibiotics for mandibular third molar surgery: a supportive or dissenting opinion

2007 ◽  
Vol 36 (11) ◽  
pp. 1007
Author(s):  
S. Rohit ◽  
B. Praveen Reddy ◽  
R. Desai ◽  
S. Manjunath ◽  
S. Shubhalakshmi ◽  
...  
Keyword(s):  
Third Molar ◽  
Prophylactic Antibiotics ◽  
Third Molar Surgery ◽  
Mandibular Third Molar ◽  
Mandibular Third Molar Surgery
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