scholarly journals Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggers autophagic cell death in human osteosarcoma cell under a spinning magnetic field

Oncotarget ◽  
2016 ◽  
Vol 8 (6) ◽  
pp. 9410-9424 ◽  
Author(s):  
Shaohua Du ◽  
Jingxiong Li ◽  
Chonghua Du ◽  
Zhongming Huang ◽  
Guangnan Chen ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Cell Death ◽  
Iron Oxide ◽  
Superparamagnetic Iron Oxide ◽  
Osteosarcoma Cell ◽  
Iron Oxide Particles ◽  
Human Osteosarcoma ◽  
Human Osteosarcoma Cell ◽  
Superparamagnetic Iron Oxide Particles ◽  
Oxide Particles

scholarly journals Magnetic microparticle concentration and collection using a mechatronic magnetic ratcheting system

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246124
Author(s):  
Oladunni B. Adeyiga ◽  
Coleman Murray ◽  
Hector E. Muñoz ◽  
Alberto Escobar ◽  
Dino Di Carlo
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Aspect Ratio ◽  
High Aspect Ratio ◽  
Concentration Factor ◽  
Magnetic Particles ◽  
Superparamagnetic Iron Oxide ◽  
Iron Oxide Particles ◽  
Superparamagnetic Iron Oxide Particles ◽  
Oxide Particles

Magnetic ratcheting cytometry is a promising approach to separate magnetically-labeled cells and magnetic particles based on the quantity of magnetic material. We have previously reported on the ability of this technique to separate magnetically-labeled cells. Here, with a new chip design, containing high aspect ratio permalloy micropillar arrays, we demonstrate the ability of this technique to rapidly concentrate and collect superparamagnetic iron oxide particles. The platform consists of a mechatronic wheel used to generate and control a cycling external magnetic field that impinges on a “ratcheting chip.” The ratcheting chip is created by electroplating a 2D array of high aspect ratio permalloy micropillars onto a glass slide, which is embedded in a thin polymer layer to create a planar surface above the micropillars. By varying magnetic field frequency and direction through wheel rotation rate and angle, we direct particle movement on chip. We explore the operating conditions for this system, identifying the effects of varying ratcheting frequency, along with time, on the dynamics and resulting concentration of these magnetic particles. We also demonstrate the ability of the system to rapidly direct the movement of superparamagnetic iron oxide particles of varying sizes. Using this technique, 2.8 μm, 500 nm, and 100 nm diameter superparamagnetic iron oxide particles, suspended within an aqueous fluid, were concentrated. We further define the ability of the system to concentrate 2.8 μm superparamagnetic iron oxide particles, present in a liquid suspension, into a small chip surface area footprint, achieving a 100-fold surface area concentration, and achieving a concentration factor greater than 200%. The achieved concentration factor of greater than 200% could be greatly increased by reducing the amount of liquid extracted at the chip outlet, which would increase the ability of achieving highly sensitive downstream analytical techniques. Magnetic ratcheting-based enrichment may be useful in isolating and concentrating subsets of magnetically-labeled cells for diagnostic automation.

Sentinel lymph node identification using superparamagnetic iron oxide particles versus radioisotope: The French Sentimag feasibility trial

2016 ◽  
Vol 113 (5) ◽  
pp. 501-507 ◽  
Author(s):  
Jean-Louis Houpeau ◽  
Marie-Pierre Chauvet ◽  
François Guillemin ◽  
Cécile Bendavid-Athias ◽  
Hélène Charitansky ◽  
...  
Keyword(s):  
Lymph Node ◽  
Iron Oxide ◽  
Sentinel Lymph Node ◽  
Superparamagnetic Iron Oxide ◽  
Feasibility Trial ◽  
Iron Oxide Particles ◽  
Sentinel Lymph Node Identification ◽  
Superparamagnetic Iron Oxide Particles ◽  
Oxide Particles

MR imaging of murine arthritis using ultrasmall superparamagnetic iron oxide particles☆

2001 ◽  
Vol 19 (9) ◽  
pp. 1209-1216 ◽  
Author(s):  
Bernard J Dardzinski ◽  
Vincent J Schmithorst ◽  
Scott K Holland ◽  
Gregory P Boivin ◽  
Tomoyuki Imagawa ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Superparamagnetic Iron Oxide ◽  
Iron Oxide Particles ◽  
Ultrasmall Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Particles ◽  
Oxide Particles
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