Modern prokinetics and their role in the treatment of gastroenterological pathology

2016 ◽  
Vol 94 (3) ◽  
pp. 178-182
Author(s):  
Arkady A. Sheptulin ◽  
I. B. Belousova
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gastrointestinal Tract ◽  
Dopamine Receptors ◽  
Dopamine Receptor ◽  
Motor Function ◽  
Reflux Disease ◽  
Beta Blockers ◽  
High Prevalence ◽  
Receptor Blockers ◽  
Irritable Bowel

The importance ofprokinetics (drugs stimulating motor function of the gastrointestinal tract} arises from the high prevalence of gastroenterological pathology associated with primary or secondary disturbances of this function in esophagus, stomach, and intestines. The main groups of prokinetics are beta-blockers of dopamine receptors, inhibitors of acetylcholine esterase (or their combination with dopamine receptor blockers), 5-HT4-receptor agonists. They find wide application for the treatment of gastroesophgeal reflux disease, functional dyspepsia and constipation, obstipational form of irritable bowel syndrome, and other conditions accompanied by motor function disorders of the gastrointestinal tract.

Combined detection of inorganic syndromes of the gastrointestinal tract and their differential diagnosis.

2021 ◽  
Vol 2021 (2) ◽  
pp. 68-71
Author(s):  
R.I. Khalafova ◽  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Differential Diagnosis ◽  
Gastrointestinal Tract ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Functional Dyspepsia ◽  
Military Personnel ◽  
Reflux Disease ◽  
Irritable Bowel ◽  
Combined Detection

To study the frequency of detection of combinations of the main syndromes of the gastrointestinal tract (GIT) and their differential diagnosis, consisting of irritable bowel syndrome (IBS), syndrome of functional dyspepsia (SFD), chronic idiopathic dyspepsia (CIT) and gastroesophageal reflux disease (GERD). The main gastrointestinal syndromes are quite often detected among different groups of military personnel and members of their families. ES plays an important role in their formation. International recommendations allow anamnestic diagnosis of each of the syndromes in separately and in combination with each other. The medical appealability of patients depends on the severity of the symptoms of the syndromes, it is most pronounced when they are combined.

Irritable bowel syndrome, gastro-oesophageal reflux disease and dyspepsia: Overlap analysis using loglinear models

2012 ◽  
Vol 13 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Asma pourhoseingholi ◽  
Mohsen Vahedi ◽  
Mohamad Amin Pourhoseingholi ◽  
Sara Ashtari ◽  
Bijan Moghimi-Dehkordi ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Reflux Disease ◽  
Oesophageal Reflux ◽  
Loglinear Models ◽  
Oesophageal Reflux Disease ◽  
Overlap Analysis ◽  
Irritable Bowel

scholarly journals Quality of Life and Level of Physical Activity In Students with and without Symptoms of Functional Dyspepsia and Irritable Bowel Syndrome Surveyed with Questionnaire “7×7” (7 Symptoms Per 7 Days)

2020 ◽  
Vol 30 (3) ◽  
pp. 36-41
Author(s):  
T. V. Zhestkova
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Irritable Bowel Syndrome ◽  
Gastrointestinal Tract ◽  
Functional Dyspepsia ◽  
Functional Disorders ◽  
Men And Women ◽  
Moderate Severity ◽  
Irritable Bowel

Aim. Assessment of the quality of life and physical activity level in students with and without symptoms of functional dyspepsia (FD) and irritable bowel syndrome (IBS) according to questionnaire “7×7” (7 symptoms per 7 days).Materials and methods. Symptoms of FD and IBS were surveyed using the “7×7” questionnaire. Level of physical activity was evaluated according to the short IPAQ, and quality of life — to WAM questionnaires.Results. The study surveyed 92 students aged 20.7 ± 0.2 years (56 men and 36 women). We report borderline manifestations of functional disorders of the gastrointestinal tract (GIT) in 51.1 %, and FD and/or IBS symptoms of mild to moderate severity in 23.9 % of respondents. Symptoms of FD and/or IBS were equally common in men and women. Severity of FD and/or IBS symptoms was rated 4 [[3; 7] in men and 4 [[4; 11] in women (p = 0.25). Physical activity of 57.6 % in students corresponded to a moderate level. Healthy students were more likely to exhibit higher physical activity than individuals with FD and/or IBS symptoms, 56.5 and 31.9 %, respectively (p = 0.04). The level of wellbeing and severity of FD and/or IBS symptoms correlated negatively (r = –0.28, p = 0.01). Wellbeing and mood correlated directly with physical activity, r = 0.33, p = 0.001 and r = 0.27, respectively (p = 0.01).Conclusions. 1. Symptoms of FD and/or IBS occur widely among students and equally in men and women. Functional disorders of the gastrointestinal tract of mild to moderate severity occur in 23.9 % of students, with borderline symptoms registered with every second individual. 2. Healthy students significantly more often exhibited higher physical activity compared to individuals with FD and/or IBS symptoms of varying severity in the ratios of 56.5 and 31.9 % (p = 0.04). 3. Severity of FD and/or IBS in students negatively correlates with the wellbeing component of quality of life (r = –0.28, p = 0.01).

Muscarinic Analgesics with Potent and Selective Effects on the Gastrointestinal Tract:  Potential Application for the Treatment of Irritable Bowel Syndrome

1997 ◽  
Vol 40 (4) ◽  
pp. 538-546 ◽  
Author(s):  
Charles H. Mitch ◽  
Thomas J. Brown ◽  
Frank P. Bymaster ◽  
David O. Calligaro ◽  
Donna Dieckman ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gastrointestinal Tract ◽  
Potential Application ◽  
Irritable Bowel ◽  
Selective Effects
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