Gene Expression Profiles of Periodontal Ligament Cells Treated With Enamel Matrix Proteins In Vitro: Analysis Using cDNA Arrays

2004 ◽  
Vol 75 (11) ◽  
pp. 1539-1546 ◽  
Author(s):  
Mohamed H. Parkar ◽  
Maurizio Tonetti
Keyword(s):  
Periodontal Ligament ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Matrix Proteins ◽  
Periodontal Ligament Cells ◽  
Enamel Matrix ◽  
Enamel Matrix Proteins ◽  
Vitro Analysis ◽  
In Vitro Analysis

Effects of enamel matrix proteins on multi-lineage differentiation of periodontal ligament cells in vitro

2013 ◽  
Vol 9 (1) ◽  
pp. 4796-4805 ◽  
Author(s):  
Harsh D. Amin ◽  
Irwin Olsen ◽  
Jonathan C. Knowles ◽  
Michel Dard ◽  
Nikolaos Donos
Keyword(s):  
Periodontal Ligament ◽  
Matrix Proteins ◽  
Periodontal Ligament Cells ◽  
Enamel Matrix ◽  
Enamel Matrix Proteins ◽  
Lineage Differentiation

Expression Profiling of Periodontal Ligament Cells Stimulated with Enamel Matrix Proteins in vitro: A Model for Tissue Regeneration

2002 ◽  
Vol 81 (11) ◽  
pp. 776-783 ◽  
Author(s):  
P.M. Brett ◽  
M. Parkar ◽  
I. Olsen ◽  
M. Tonetti
Keyword(s):  
Periodontal Ligament ◽  
Gene Array ◽  
Periodontal Regeneration ◽  
Matrix Proteins ◽  
Periodontal Ligament Cells ◽  
Enamel Matrix ◽  
Enamel Matrix Proteins ◽  
Genetic Responses

Several studies have examined the role of enamel matrix proteins in root formation and periodontal regeneration, although most of these have focused on a few specific genes which had previously been implicated. However, recent advances in expressional profiling have made it possible to examine the range of genetic responses involved in these processes. In the present experiments, we have therefore utilized this technique to determine the effects of enamel matrix proteins on the gene activities of periodontal ligament cells in vitro. Such cells were found to have an elevated level of RNA synthesis compared with control cells. Moreover, hybridization of the cDNA prepared from this RNA to gene array filters showed that there was differential expression of 121 genes, most of which had not previously been associated with periodontal regeneration. Some of these selective changes in gene activity might thus reflect the fundamental events that underlie periodontal development.

scholarly journals Interaction of enamel matrix proteins with human periodontal ligament cells

2015 ◽  
Vol 20 (2) ◽  
pp. 339-347 ◽  
Author(s):  
Harsh D. Amin ◽  
Irwin Olsen ◽  
Jonathan Knowles ◽  
Michel Dard ◽  
Nikolaos Donos
Keyword(s):  
Periodontal Ligament ◽  
Matrix Proteins ◽  
Periodontal Ligament Cells ◽  
Enamel Matrix ◽  
Enamel Matrix Proteins ◽  
Human Periodontal Ligament Cells

Gene profile in periodontal ligament cells and clones with enamel matrix proteins derivative

2007 ◽  
Vol 34 (7) ◽  
pp. 599-609 ◽  
Author(s):  
Idit Barkana ◽  
Eleni Alexopoulou ◽  
Shoshi Ziv ◽  
Jasmin Jacob-Hirsch ◽  
Ninette Amariglio ◽  
...  
Keyword(s):  
Periodontal Ligament ◽  
Matrix Proteins ◽  
Periodontal Ligament Cells ◽  
Enamel Matrix ◽  
Gene Profile ◽  
Enamel Matrix Proteins
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