scholarly journals Catatonia as a presenting symptom of ectopic adrenocorticotropic hormone syndrome caused by thymic carcinoid tumor

2018 ◽  
Vol 128 (6) ◽  
pp. 389-391 ◽  
Author(s):  
Seung Shin Park ◽  
Sung Hye Kong ◽  
Ye Seul Yang ◽  
Chang Ho Ahn ◽  
Jung Hee Kim
Keyword(s):  
Carcinoid Tumor ◽  
Adrenocorticotropic Hormone ◽  
Thymic Carcinoid ◽  
Thymic Carcinoid Tumor ◽  
Ectopic Adrenocorticotropic Hormone

scholarly journals [18F]fluoro-2-deoxy-d-glucose ([18F]FDG) positron emission tomography imaging of thymic carcinoid tumor presenting with recurrent Cushing’s syndrome

2005 ◽  
Vol 152 (4) ◽  
pp. 521-525 ◽  
Author(s):  
Athina Markou ◽  
Patrick Manning ◽  
Banu Kaya ◽  
Sam N Datta ◽  
Jamshed B Bomanji ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
High Resolution ◽  
Carcinoid Tumor ◽  
Fdg Pet ◽  
Pet Scan ◽  
Emission Tomography ◽  
Thymic Carcinoid ◽  
Acth Secretion ◽  
Positron Emission ◽  
Thymic Carcinoid Tumor

We report a case of a young woman with Cushing’s syndrome (CS), in whom although endocrine investigations and negative pituitary imaging were suggestive of ectopic ACTH secretion, the results of inferior petrosal sinus (IPS) sampling after coricotropin-releasing hormone (CRH) stimulation were suggestive of pituitary ACTH hypersecretion. 111In-labelled octreotide and high-resolution computer tomography (CT) revealed a lesion possibly responsible for the ACTH source in the thymus. Thymectomy confirmed concomitant ectopic CRH and probable ACTH production by a thymic neuroendocrine carcinoma. After an 8-year remission period the patient developed a clinical and biochemical relapse. A high-resolution computed tomography (CT) scan of the thorax showed a 2-cm nodule in the thymic bed, which was positive on a [18F]fluoro-2-deoxy-d-glucose ([18F]FDG) positron emission tomography (PET) scan. However, a repeated thymectomy did not result in remission. A repeat [18F]FDG PET study showed persistent disease in the thymic bed and also uptake in the adrenals. The patient underwent bilateral adrenalectomy, which resulted in clinical remission. A further [18F]FDG PET scan 8 months later showed no progression of the thymic tumor and confirmed complete excision of the adrenals. This is a rare case of concomitant CRH and ACTH secretion from a thymic carcinoid tumor; the case illustrates the usefulness of functional imaging with [18F]FDG PET in the diagnosis, management and follow-up of neuroendocrine tumors.

ULTRASTRUGTURAL STUDIES OF A THYMIC CARCINOID TUMOR

1980 ◽  
Vol 30 (4) ◽  
pp. 651-658 ◽  
Author(s):  
Hiroshi Kaneko ◽  
Shinobu Ishikawa ◽  
Toshiko Sumida ◽  
Masao Sekiya ◽  
Muneatsu Toshima ◽  
...  
Keyword(s):  
Carcinoid Tumor ◽  
Thymic Carcinoid ◽  
Thymic Carcinoid Tumor

scholarly journals Diagnosis and management of small pulmonary atypical carcinoid tumor associated with Cushing syndrome

2020 ◽  
Vol 9 (4) ◽  
Author(s):  
Dathe Z Benissan-Messan ◽  
Robert E Merritt ◽  
Konstantin Shilo ◽  
Desmond M D'Souza ◽  
Peter J Kneuertz
Keyword(s):  
Carcinoid Tumor ◽  
Adrenocorticotropic Hormone ◽  
Cushing Syndrome ◽  
Wedge Resection ◽  
Lung Nodule ◽  
Pet Scan ◽  
Atypical Carcinoid ◽  
Pulmonary Carcinoid ◽  
Ectopic Adrenocorticotropic Hormone

Ectopic adrenocorticotropic hormone ( ACTH) syndrome is rare and identification of its source is often challenging. We report the case of an ectopic Cushing syndrome in a young adult male secondary to an occult ACTH producing atypical carcinoid tumor. Extensive biochemical and imaging workup was unrevealing. The diagnosis was aided by Ga-DOTA PET scan demonstrating a suspicious left upper lobe lung nodule. The patient underwent video-assisted thoracoscopic exploration with wedge resection and mediastinal lymphadenectomy of a T2aN2M0 atypical carcinoid, resulting in the normalization of ACTH levels and complete resolution of symptoms. The role of a Ga-DOTA PET scan in diagnosing pulmonary carcinoid tumors and their management are discussed.

Imaging of a Mediastinal Thymic Carcinoid Tumor With Radiolabeled Somatostatin Analogue

1996 ◽  
Vol 21 (6) ◽  
pp. 487-488 ◽  
Author(s):  
DANIEL G. CADIGAN ◽  
PETER D. HOLLETT ◽  
PETER W. COLLINGWOOD ◽  
EHUD UR
Keyword(s):  
Carcinoid Tumor ◽  
Somatostatin Analogue ◽  
Thymic Carcinoid ◽  
Thymic Carcinoid Tumor

Thymic carcinoid tumor

2003 ◽  
Vol 51 (1) ◽  
pp. 29-31 ◽  
Author(s):  
Masaya Tamura ◽  
Yasuhiko Ohta ◽  
Makoto Oda ◽  
Go Watanabe
Keyword(s):  
Carcinoid Tumor ◽  
Thymic Carcinoid ◽  
Thymic Carcinoid Tumor

Chemical Characterization of Ectopic ACTH Purified From a Malignant Thymic Carcinoid Tumor

1976 ◽  
Vol 43 (4) ◽  
pp. 831-835 ◽  
Author(s):  
P. J. LOWRY ◽  
LESLEY H. REES ◽  
SUSAN TOMLIN ◽  
GLENDA GILLIES ◽  
J. LANDON
Keyword(s):  
Carcinoid Tumor ◽  
Chemical Characterization ◽  
Thymic Carcinoid ◽  
Ectopic Acth ◽  
Thymic Carcinoid Tumor

scholarly journals CUSHING SYNDROME DUE TO ECTOPIC ADRENOCORTICOTROPIC HORMONE SECRETION BY A PULMONARY CARCINOID TUMOR IN A PATIENT WITH PNEUMOCONIOSIS

2018 ◽  
Vol 4 (6) ◽  
pp. e521-e526
Author(s):  
Hazim Bukamur ◽  
Chelsey White ◽  
Rodhan Khthir ◽  
Alysia Browne ◽  
Fauzi Najar ◽  
...  
Keyword(s):  
Carcinoid Tumor ◽  
Adrenocorticotropic Hormone ◽  
Cushing Syndrome ◽  
Hormone Secretion ◽  
Pulmonary Carcinoid ◽  
Ectopic Adrenocorticotropic Hormone

Cushing syndrome: a rare presentation of bronchial carcinoid tumor

2019 ◽  
Vol 27 (7) ◽  
pp. 603-605
Author(s):  
Pavneet Kohli ◽  
Prasanth Penumadu ◽  
K Chandrashekhar Rao ◽  
Sreevathsa KS Prasad ◽  
Sadishkumar Kamalanathan
Keyword(s):  
Carcinoid Tumor ◽  
Adrenocorticotropic Hormone ◽  
Cushing Syndrome ◽  
Imaging Techniques ◽  
Hormone Secretion ◽  
Clinical Feature ◽  
Bronchial Carcinoid ◽  
Rare Presentation ◽  
Pulmonary Carcinoid ◽  
Ectopic Adrenocorticotropic Hormone

Cushing syndrome is a very rare clinical feature of typical pulmonary carcinoid, caused by hypercorticism, and despite advances in imaging techniques, it poses a difficult diagnostic and therapeutic challenge. We report the case of a patient presenting with Cushing syndrome associated with ectopic adrenocorticotropic hormone secretion from a bronchial carcinoid, whose management presented diagnostic and therapeutic challenges.

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