scholarly journals Gastroesophageal reflux disease, functional dyspepsia and irritable bowel syndrome: common overlapping gastrointestinal disorders

Author(s):  
Nicola de Bortoli
2021 ◽  
Vol 2021 (2) ◽  
pp. 68-71
Author(s):  
R.I. Khalafova ◽  

To study the frequency of detection of combinations of the main syndromes of the gastrointestinal tract (GIT) and their differential diagnosis, consisting of irritable bowel syndrome (IBS), syndrome of functional dyspepsia (SFD), chronic idiopathic dyspepsia (CIT) and gastroesophageal reflux disease (GERD). The main gastrointestinal syndromes are quite often detected among different groups of military personnel and members of their families. ES plays an important role in their formation. International recommendations allow anamnestic diagnosis of each of the syndromes in separately and in combination with each other. The medical appealability of patients depends on the severity of the symptoms of the syndromes, it is most pronounced when they are combined.


Author(s):  
William C. Orr

Sleep is associated with substantial changes in gastrointestinal functioning that have considerable clinical relevance Symptoms of sleep-related dysfunction are common and are primarily related to sleep-related heartburn and regurgitation. Sleep disturbances accompany several other gastrointestinal disorders, such as irritable bowel syndrome (IBS). Sleep-related gastroesophageal reflux (GER) has been shown to plan a major role in the pathogenesis of more complicated gastroesophageal reflux disease (GERD), notably via a prolongation of acid contact. Mucosal damage has been shown to be more closely associated with this pattern of reflux in comparison with waking reflux, which is associated with more frequent but very short reflux events. Sleep disturbance is also associated with a visceral hyperalgesia that enhances pain responses associated with acid–mucosal contact. Sleep does influence intestinal motility, but further research is needed to confirm the details of exactly how intestinal motility is modulated by sleep.


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